GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury

scientific article published on 8 December 2017

GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41598-017-17574-W
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/s41598-017-17574-w
P932PMC publication ID5722931
P698PubMed publication ID29222479

P50authorHyon-Seung YiQ64515654
Minho ShongQ67522725
So Yeon KimQ88330791
P2093author name stringHyo Kyun Chung
Koon Soon Kim
Jung Tae Kim
Hyeon-Woo Kim
Minjoo Kwon
P2860cites workGrowth Differentiation Factor-15: Induction in Liver Injury Through p53 and Tumor Necrosis Factor-Independent Mechanisms1Q63322960
Binding of carbon tetrachloride metabolites to rat hepatic mitochondrial DNAQ70602735
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in miceQ77598616
An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in miceQ77922003
Effect of dietary fat on chronic ethanol-induced oxidative stress in hepatocytesQ78115816
Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liverQ82891695
Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in miceQ37413654
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.Q37576614
A prospective study of macrophage inhibitory cytokine-1 (MIC-1/GDF15) and risk of colorectal cancerQ37696690
Interaction of hepatic stellate cells with diverse types of immune cells: foe or friend?Q38121575
Mechanisms of hepatic stellate cell activationQ39294420
The TGF-β superfamily cytokine, MIC-1/GDF15: a pleotrophic cytokine with roles in inflammation, cancer and metabolism.Q39492314
Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in miceQ41548774
Hepatic fibrosis after long-term administration of ethanol and moderate vitamin A supplementation in the rat.Q42254818
ANGPTL6 expression is coupled with mitochondrial OXPHOS function to regulate adipose FGF21.Q42803053
ICAM-1 is involved in the mechanism of alcohol-induced liver injury: studies with knockout miceQ43607619
A role for interleukin-10 in alcohol-induced liver sensitization to bacterial lipopolysaccharideQ43872901
Effect of ethanol intake on rat liver mitochondrial respiration and oxidative phosphorylationQ46116349
The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation.Q46807844
Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosisQ48055490
Characterization of growth-differentiation factor 15, a transforming growth factor beta superfamily member induced following liver injuryQ24554213
Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammationQ24682128
A simple method for the isolation and purification of total lipides from animal tissuesQ25939009
Role of mitochondria in alcoholic liver diseaseQ26864954
Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injuryQ28251154
Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistanceQ28510149
GDF-15 for prognostication of cardiovascular and cancer morbidity and mortality in menQ28535575
Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytesQ28579862
Mitochondrial abnormalities in non-alcoholic steatohepatitisQ30304277
Animals models of gastrointestinal and liver diseases. Animal models of alcohol-induced liver disease: pathophysiology, translational relevance, and challengesQ33626594
Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by LipopolysaccharideQ33682931
Macrophage inhibitory cytokine 1 (MIC-1/GDF15) as a novel diagnostic serum biomarker in pancreatic ductal adenocarcinomaQ34045939
GDF15 Is a Novel Biomarker for Impaired Fasting GlucoseQ34750077
Association of serum level of growth differentiation factor 15 with liver cirrhosis and hepatocellular carcinomaQ35634311
NF-κB in the liver--linking injury, fibrosis and hepatocellular carcinomaQ35808323
GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction.Q35920919
Mitochondrial roles and cytoprotection in chronic liver injuryQ36055801
The liver as an immunological organQ36382243
Rodent models of alcoholic liver disease: of mice and men.Q36395131
Dynamic adaptation of liver mitochondria to chronic alcohol feeding in mice: biogenesis, remodeling, and functional alterations.Q36452001
Alcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in miceQ36901235
Hepatic immunophenotyping for streptozotocin-induced hyperglycemia in miceQ37134825
Inflammatory pathways in liver homeostasis and liver injuryQ37207091
Mouse model of chronic and binge ethanol feeding (the NIAAA model)Q37210744
Muscle mitohormesis promotes longevity via systemic repression of insulin signalingQ37377087
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)17238
P577publication date2017-12-08
P1433published inScientific ReportsQ2261792
P1476titleGDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury
P478volume7

Reverse relations

cites work (P2860)
Q57066901Candidate Biomarkers of Liver Fibrosis: A Concise, Pathophysiology-oriented Review
Q58697982GDF15 Regulates Malat-1 Circular RNA and Inactivates NFκB Signaling Leading to Immune Tolerogenic DCs for Preventing Alloimmune Rejection in Heart Transplantation
Q61810426Gene Expression Profiling in Ischemic Postconditioning to Alleviate Mouse Liver Ischemia/Reperfusion Injury
Q88537974Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice
Q64064974Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases
Q55257930Matrix Remodeling Associated 7 Deficiency Alleviates Carbon Tetrachloride-Induced Acute Liver Injury in Mice.
Q58705640Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches
Q89601774Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury
Q90737854Targeting of Secretory Proteins as a Therapeutic Strategy for Treatment of Nonalcoholic Steatohepatitis (NASH)
Q57299043The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases
Q64255858Unsupervised identification of disease states from high-dimensional physiological and histopathological profiles

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