Mkrn3 functions as a novel ubiquitin E3 ligase to inhibit Nptx1 during puberty initiation

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Mkrn3 functions as a novel ubiquitin E3 ligase to inhibit Nptx1 during puberty initiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.19347
P932PMC publication ID5689596
P698PubMed publication ID29156706

P2093author name stringHuifang Liu
Fengling Chen
Xiangxin Kong
P2860cites workThe effect of leptin on luteinizing hormone release is exerted in the zona incerta and mediated by melanin-concentrating hormoneQ38306905
Causes, diagnosis, and treatment of central precocious pubertyQ38725191
In silico analysis of a novel MKRN3 missense mutation in familial central precocious puberty.Q40738493
Effects of NELL2 on the regulation of GnRH expression and puberty in female ratsQ42194972
Selective expression of Narp, a secreted neuronal pentraxin, in orexin neuronsQ44158613
Molecular and gene network analysis of thyroid transcription factor 1 (TTF1) and enhanced at puberty (EAP1) genes in patients with GnRH-dependent pubertal disorders.Q45382794
NPTX1 regulates neural lineage specification from human pluripotent stem cellsQ47916005
A missense mutation in MKRN3 in a Danish girl with central precocious puberty and her brother with early pubertyQ48139111
Imprinting of a RING zinc-finger encoding gene in the mouse chromosome region homologous to the Prader-Willi syndrome genetic regionQ48242077
Expression of EAP1 and CUX1 in the hypothalamus of female rats and relationship with KISS1 and GnRH.Q48702391
Releasing the brake on puberty.Q50935565
Circulating MKRN3 Levels Decline During Puberty in Healthy Boys.Q52670306
Circulating makorin ring-finger protein-3 (MKRN3) levels in healthy men and in men with hypogonadotropic hypogonadismQ58035102
Mutations in the maternally imprinted gene MKRN3 are common in familial central precocious pubertyQ86363486
A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical regionQ22009166
Mouse and human neuronal pentraxin 1 (NPTX1): conservation, genomic structure, and chromosomal localizationQ24315655
A new pathway in the control of the initiation of puberty: the MKRN3 geneQ26861068
Structure of pentameric human serum amyloid P componentQ27731194
RING domain E3 ubiquitin ligasesQ27860546
The I-TASSER Suite: protein structure and function prediction.Q30370293
ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimersQ33760362
A genomic atlas of mouse hypothalamic developmentQ33795412
Constructing and decoding unconventional ubiquitin chains.Q34182233
Central precocious puberty caused by mutations in the imprinted gene MKRN3.Q34348835
Central precocious puberty in a girl and early puberty in her brother caused by a novel mutation in the MKRN3 geneQ34398621
Low Frequency of MKRN3 Mutations in Central Precocious Puberty Among Korean GirlsQ34474893
Developmental changes in embryonic hypothalamic neurons during prenatal fat exposureQ37175024
Pubertal development and regulationQ37538376
New causes of central precocious puberty: the role of genetic factors.Q38239266
Gene expression profiling of hypothalamic hamartomas: a search for genes associated with central precocious pubertyQ38295674
P433issue49
P407language of work or nameEnglishQ1860
P304page(s)85102-85109
P577publication date2017-07-18
P1433published inOncotargetQ1573155
P1476titleMkrn3 functions as a novel ubiquitin E3 ligase to inhibit Nptx1 during puberty initiation
P478volume8

Reverse relations

cites work (P2860)
Q88715030Genetics of pubertal timing
Q64244074MKRN3 Interacts With Several Proteins Implicated in Puberty Timing but Does Not Influence Expression

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