Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer

scientific article published on 3 January 2018

Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1100160870
P356DOI10.1186/S13039-017-0348-Y
P932PMC publication ID5753467
P698PubMed publication ID29308088

P50authorJeremy A. SquireQ39802515
P2093author name stringDaniel Guimarães Tiezzi
Jeremy A. Squire
Thiago Vidotto
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Integrated analysis of the genomic instability of PTEN in clinically insignificant and significant prostate cancerQ35854235
MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinomaQ36605100
Mutational Landscape of Aggressive Prostate Tumors in African American MenQ36633535
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Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH.Q38833458
DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancerQ38893748
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Androgen deprivation leads to increased carbohydrate metabolism and hexokinase 2-mediated survival in Pten/Tp53-deficient prostate cancerQ39634850
The Identification of Microdeletion and Reciprocal Microduplication in 22q11.2 Using High-Resolution CMA TechnologyQ40140280
In prostate cancer needle biopsies, detections of PTEN loss by fluorescence in situ hybridization (FISH) and by immunohistochemistry (IHC) are concordant and show consistent association with upgradingQ40919195
A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancerQ40978920
Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genomeQ41870312
Cancer Prognosis Defined by the Combined Analysis of 8q, PTEN and ERG.Q42356687
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A Single-Nucleotide Substitution Mutator Phenotype Revealed by Exome Sequencing of Human Colon AdenomasQ57161434
PTEN genomic deletions that characterize aggressive prostate cancer originate close to segmental duplicationsQ57790325
Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline†Q63432946
ThePTEN gene in locally progressive prostate cancer is preferentially inactivated by bi-allelic gene deletionQ63966367
Targeted inactivation of p53 in human cells does not result in aneuploidyQ77678749
P4510describes a project that usesCytoscapeQ3699942
P304page(s)1
P577publication date2018-01-03
P1433published inMolecular CytogeneticsQ15761790
P1476titleDistinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer
P478volume11

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cites work (P2860)
Q92445464Detection and Correlation of Single and Concomitant TP53, PTEN, and CDKN2A Alterations in Gliomas
Q93196102Emerging role of PTEN loss in evasion of the immune response to tumours
Q93046038Identifying small molecule probes of ENTPD5 through high throughput screening
Q92702101PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?
Q52723228Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.
Q55323049Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems.

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