A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis

scientific article published on 28 September 2017

A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.OMTM.2017.09.004
P932PMC publication ID5744068
P698PubMed publication ID29296626

P50authorDavid A. DichekQ124980566
Nagadhara DronadulaQ124980778
P2093author name stringBradley K Wacker
Lianxiang Bi
Emma Bueren
Ervin Ham
P2860cites workA simple method for the isolation and purification of total lipides from animal tissuesQ25939009
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Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapyQ34382972
Understanding and treating vein graft atherosclerosisQ34934966
Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteriesQ34993431
Efficient gene transfer and durable transgene expression in grafted rabbit veinsQ34999733
Helper-dependent adenoviral vector achieves prolonged, stable expression of interleukin-10 in rabbit carotid arteries but does not limit early atherogenesisQ35174913
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Gene therapy and vein graft patency in coronary artery bypass graft surgeryQ45888569
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Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: impact on transgene expression and endothelial functionQ47904531
Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesisQ64378257
Local gene transfer of tissue inhibitor of metalloproteinase-2 influences vein graft remodeling in a mouse modelQ64379606
Adenovirus-mediated gene transfer of human inducible nitric oxide synthase in porcine vein grafts inhibits intimal hyperplasiaQ64379705
Adenoviral-mediated inhibition of G beta gamma signaling limits the hyperplastic response in experimental vein graftsQ64381994
The severity of atherosclerosis at sites of plaque rupture with occlusive thrombosis in saphenous vein coronary artery bypass graftsQ68024894
Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass graftsQ68156084
Immunocytochemical analysis of cellular components in atherosclerotic lesions. Use of monoclonal antibodies with the Watanabe and fat-fed rabbitQ69657544
The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass graftsQ71966442
The effects of extremely low shear stress on cellular proliferation and neointimal thickening in the failing bypass graftQ74131957
Patencies of 2127 arterial to coronary conduits over 15 yearsQ75271509
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Understanding saphenous vein graft patencyQ84570510
Statin therapy and saphenous vein graft disease after coronary bypass surgery: analysis from the CASCADE randomized trialQ85015350
???Q28074173
Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasiaQ35769081
A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signalQ35915922
Pathology of drug-eluting versus bare-metal stents in saphenous vein bypass graft lesionsQ36126274
Radial artery vs saphenous vein graft used as the second conduit for surgical myocardial revascularization: long-term clinical follow-upQ36164691
Cholesterol efflux analyses using stable isotopes and mass spectrometryQ36480687
Atherosclerosis: Successes, Surprises, and Future ChallengesQ36602802
Gene therapy for the prevention of vein graft diseaseQ36698258
Relationship between vein graft failure and subsequent clinical outcomes after coronary artery bypass surgeryQ36975536
Coronary-Artery Bypass Surgery in Patients with Ischemic CardiomyopathyQ37078225
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Saphenous vein grafts with multiple versus single distal targets in patients undergoing coronary artery bypass surgery: one-year graft failure and five-year outcomes from the Project of Ex-Vivo Vein Graft Engineering via Transfection (PREVENT) IV trQ37485187
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Stranger in a strange land: the pathogenesis of saphenous vein graft stenosis with emphasis on structural and functional differences between veins and arteriesQ37772604
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Saphenous vein graft failure after coronary artery bypass surgery: pathophysiology, management, and future directionsQ38098012
Effects of aggressive statin therapy on patients with coronary saphenous vein bypass grafts: a systematic review and meta-analysis of randomized, controlled trialsQ38128022
Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapyQ38302443
Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trialQ38411135
Radial artery grafts vs saphenous vein grafts in coronary artery bypass surgery: a randomized trial.Q38495903
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Endothelial fluid shear stress sensing in vascular health and disease.Q38630594
Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosisQ38647828
Cardiovascular Gene Therapy: Past, Present, and FutureQ38733395
Coronary-Artery Bypass GraftingQ38837494
Vein graft failure: from pathophysiology to clinical outcomes.Q38837879
Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10.Q39189210
Adenoviral-mediated gene transfer of a constitutively active form of the retinoblastoma gene product attenuates neointimal thickening in experimental vein graftsQ39501012
Long-Term Mortality After Coronary Revascularization in Nondiabetic Patients With Multivessel DiseaseQ39641675
Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapyQ39876759
Randomized Trial of Bilateral versus Single Internal-Thoracic-Artery GraftsQ40427394
High Pulsatility Flow Induces Acute Endothelial Inflammation through Overpolarizing Cells to Activate NF-κB.Q40464742
Coronary artery bypass graft disease.Q40474971
Gene delivery to aortocoronary saphenous vein grafts in a large animal model of intimal hyperplasiaQ40534630
Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre.Q41152221
Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, and preventionQ41729196
HHF35, a muscle-actin-specific monoclonal antibody. I. Immunocytochemical and biochemical characterizationQ42050958
Atherosclerosis in rabbit vein graftsQ43876879
Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesisQ44121998
P921main subjectAdenoviridaeQ193447
atherosclerosisQ12252367
P304page(s)96-111
P577publication date2017-09-28
P1433published inMolecular Therapy. Methods & Clinical DevelopmentQ27725341
P1476titleA Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis
P478volume7

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Q57046350ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammationcites workP2860

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