Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP.

scientific article published on 28 November 2017

Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0188010
P8608Fatcat IDrelease_6gz45wzvebdq5njyouknhfztja
P932PMC publication ID5705076
P698PubMed publication ID29182620

P50authorMichael RothQ38329018
P2093author name stringChristian Pasquali
Daiana Stolz
Michael Tamm
P2860cites workThe oral administration of bacterial extracts prevents asthma via the recruitment of regulatory T cells to the airwaysQ84974054
The immunostimulant OM-85 BV prevents wheezing attacks in preschool childrenQ85155651
A bacterial extract of OM-85 Broncho-Vaxom prevents allergic rhinitis in miceQ87647662
[Influence of OM-85 BV on hBD-1 and immunoglobulin in children with asthma and recurrent respiratory tract infection]Q95383004
Th1-orientated immunological properties of the bacterial extract OM-85-BV.Q46537472
Constitutive high expression of protein arginine methyltransferase 1 in asthmatic airway smooth muscle cells is caused by reduced microRNA-19a expression and leads to enhanced remodeling.Q47999327
The bacterial extract OM-85 BV protects mice against influenza and Salmonella infectionQ50047895
Rhinovirus increases human beta-defensin-2 and -3 mRNA expression in cultured bronchial epithelial cells.Q51660498
[Experience with bronchomunal used in the combined treatment of patients with bronchial asthma and chronic obstructive pulmonary disease].Q53887852
C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells.Q54770577
Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophagesQ57209758
Relative Contribution of C1q and Apoptotic Cell-Surface Calreticulin to Macrophage PhagocytosisQ58212954
Upregulation of adhesion molecules induced by broncho-vaxom on phagocytic cellsQ67520372
Local immunity in patients with chronic bronchitis and the effects of a bacterial extract, Broncho-Vaxom, on T lymphocytes, macrophages, gamma-interferon and secretory immunoglobulin A in bronchoalveolar lavage fluid and other variablesQ68365018
Heat shock-sensitive expression of calreticulin. In vitro and in vivo up-regulationQ71921343
OM-8BV for COPDQ73977394
Effect of bacterial antigen lysate on IgG and IgA levels in children with recurrent infections and hypogammaglobulinemiaQ78019360
Interleukin-17A modulates human airway epithelial responses to human rhinovirus infectionQ80421882
Airway epithelium-derived transforming growth factor-beta is a regulator of fibroblast proliferation in both fibrotic and normal subjectsQ81337427
Mechanism of human rhinovirus infectionsQ26744124
Antiviral mechanisms of human defensinsQ27023010
Bacterial lysates improve the protective antibody response against respiratory viruses through Toll-like receptor 4.Q33723524
OM85-BV induced the productions of IL-1β, IL-6, and TNF-α via TLR4- and TLR2-mediated ERK1/2/NF-κB pathway in RAW264.7 cellsQ33842318
An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation.Q34916830
Enhanced Mucosal Antibody Production and Protection against Respiratory Infections Following an Orally Administered Bacterial ExtractQ34930189
The interaction of endothelin-1 and TGF-β1 mediates vascular cell remodelingQ34981727
Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathwayQ35080072
Human thymus medullary epithelial cells promote regulatory T-cell generation by stimulating interleukin-2 production via ICOS ligandQ35966267
Antigen targeting to M cells for enhancing the efficacy of mucosal vaccinesQ37679436
Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tractQ37680163
OM-85 is an immunomodulator of interferon-β production and inflammasome activity.Q37682178
OM-85 BV, an immunostimulant in pediatric recurrent respiratory tract infections: a systematic reviewQ37689585
Epithelial injury and repair in airways diseases.Q38168099
Intercellular adhesion molecule-1 as a drug target in asthma and rhinitisQ38201154
Immunoregulatory and immunostimulatory responses of bacterial lysates in respiratory infections and asthmaQ38370752
Rhinoviruses and Their Receptors: Implications for Allergic DiseaseQ38767263
Selective enhancement of systemic Th1 immunity in immunologically immature rats with an orally administered bacterial extractQ39520512
The ICOS-ligand B7-H2, expressed on human type II alveolar epithelial cells, plays a role in the pulmonary host defense systemQ40301284
Value of adding a polyvalent mechanical bacterial lysate to therapy of COPD patients under regular treatment with salmeterol/fluticasoneQ40389667
Impact of a mixed bacterial lysate (OM-85 BV) on the immunogenicity, safety and tolerability of inactivated influenza vaccine in children with recurrent respiratory tract infectionQ42228119
Four years of immunization with OM-85 BV to prevent respiratory infections in HIV+ patientsQ42724109
A bacterial extract of OM-85 Broncho-Vaxom prevents allergic rhinitis in miceQ43640287
Recombinant murine calreticulin fragment 39-272 expands CD1d(hi)CD5+ IL-10-secreting B cells that modulate experimental autoimmune encephalomyelitis in C57BL/6 miceQ44049914
A clinically approved oral vaccine against pneumotropic bacteria induces the terminal maturation of CD83+ immunostimulatory dendritic cells.Q44335067
Oral administration of bacterial lysates attenuates experimental food allergyQ44418488
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)e0188010
P577publication date2017-11-28
P1433published inPLOS OneQ564954
P1476titleBroncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP.
P478volume12

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cites work (P2860)
Q58694823Evidence that a primary anti-viral stimulation of the immune response by OM-85 reduces susceptibility to a secondary respiratory bacterial infection in mice
Q55714629Nonspecific immunomodulators for recurrent respiratory tract infections, wheezing and asthma in children: a systematic review of mechanistic and clinical evidence.
Q61804563Pelargonium sidoides radix extract EPs 7630 reduces rhinovirus infection through modulation of viral binding proteins on human bronchial epithelial cells
Q60951067Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

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