DISC1 Regulates the Proliferation and Migration of Mouse Neural Stem/Progenitor Cells through Pax5, Sox2, Dll1 and Neurog2.

scientific article published on 29 August 2017

DISC1 Regulates the Proliferation and Migration of Mouse Neural Stem/Progenitor Cells through Pax5, Sox2, Dll1 and Neurog2. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FNCEL.2017.00261
P932PMC publication ID5581844
P698PubMed publication ID28900388

P2093author name stringYi Li
Bo Xiao
Zhaohui Luo
Qian Wu
Li Feng
Yi Shu
Weiting Tang
Zongwei Yue
P2860cites workExpression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPsQ46970805
Decreased levels of disrupted-in-schizophrenia 1 (DISC1) are associated with expansion of the dentate granule cell layer in normal and kindled ratsQ48003857
Sustained vs. oscillating expressions of Ngn2, Dll1 and Hes1: a model of neural differentiation of embryonic telencephalonQ48123226
Methods to culture, differentiate, and characterize neural stem cells from the adult and embryonic mouse central nervous systemQ48280808
Genetic association and post-mortem brain mRNA analysis of DISC1 and related genes in schizophreniaQ48506149
Regulation of neuronal differentiation at the neurogenic wavefront.Q51358497
Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune functionQ51578905
Disrupted-in-Schizophrenia-1 (Disc1) is necessary for migration of the pyramidal neurons during mouse hippocampal developmentQ51868690
Migration of cardiac neural crest cells in Splotch embryosQ52169435
Regulation of Pax-3 expression in the dermomyotome and its role in muscle developmentQ52217598
RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis.Q53135944
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAPQ58326934
Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cellsQ72374761
Pax3, Neural Crest and Cardiovascular DevelopmentQ83200069
Endogenous Nitric Oxide Generation Linked to Ryanodine Receptors Activates Cyclic GMP / Protein Kinase G Pathway for Cell Proliferation of Neural Stem/Progenitor Cells Derived From Embryonic HippocampusQ83288461
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophreniaQ24306904
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cellsQ24317003
Disc1 regulates granule cell migration in the developing hippocampusQ24317940
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signalingQ24322974
Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.Q24535773
CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancerQ24610723
In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampusQ24683755
Neuronal migration abnormalities and its possible implications for schizophreniaQ26824953
Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.Q27322653
The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteinsQ28141122
Disruption of two novel genes by a translocation co-segregating with schizophreniaQ28144559
Genetic studies of bipolar affective disorder in large familiesQ28206008
The role of genes involved in neuroplasticity and neurogenesis in the observation of a gene-environment interaction (GxE) in schizophreniaQ28248230
Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondriaQ28259578
Understanding the role of DISC1 in psychiatric disease and during normal developmentQ28261398
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testisQ28263987
Localization of the 5’ end of the MCF2 oncogene to human chromosome 15q15→q23Q28268722
DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illnessQ28287390
FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil regionQ28297866
DISC1-binding proteins in neural development, signalling and schizophreniaQ28302106
Role of Sox2 in the development of the mouse neocortexQ28505312
Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb budQ28506228
Expression of Neurogenin 1 in Mouse Embryonic Stem Cells Directs the Differentiation of Neuronal Precursors and Identifies Unique Patterns of Down‐stream Gene ExpressionQ28506854
Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brainQ28507690
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brainQ28507787
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212Q28513802
The effect of amygdala kindling on hippocampal neurogenesis coincides with decreased reelin and DISC1 expression in the adult dentate gyrusQ28571917
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex developmentQ28582746
DISC1, PDE4B, and NDE1 at the centrosome and synapseQ28585118
DISC1-dependent switch from progenitor proliferation to migration in the developing cortexQ28585480
SOX3 is required during the formation of the hypothalamo-pituitary axisQ28587871
A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical developmentQ30847710
Genetic studies of bipolar affective disorder in large families.Q33949602
NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1)Q34080373
Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAiQ34172976
Linking neurodevelopmental and synaptic theories of mental illness through DISC1Q34233683
Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in miceQ34574484
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.Q34806146
Expression of mutant human DISC1 in mice supports abnormalities in differentiation of oligodendrocytesQ35115817
Sox2 Activates Cell Proliferation and Differentiation in the Respiratory EpitheliumQ35132159
Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophreniaQ35569556
DISC1-mediated dysregulation of adult hippocampal neurogenesis in ratsQ35777839
Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophreniaQ35804056
A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditionsQ36517223
Multiple roles for Sox2 in the developing and adult mouse tracheaQ37186879
An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migrationQ37611569
DISCopathies: brain disorders related to DISC1 dysfunctionQ37732176
DISC1-related signaling pathways in adult neurogenesis of the hippocampus.Q38077009
Revisiting disrupted-in-schizophrenia 1 as a scaffold proteinQ38119917
Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.Q38334695
The beta-catenin/VegT-regulated early zygotic gene Xnr5 is a direct target of SOX3 regulation.Q38349754
Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouseQ38361129
PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1Q39366533
Design and interpretation of microRNA-reporter gene activity.Q39453262
PAX5alpha enhances the epithelial behavior of human mammary carcinoma cellsQ39733214
Xenopus Sox3 activates sox2 and geminin and indirectly represses Xvent2 expression to induce neural progenitor formation at the expense of non-neural ectodermal derivativesQ41896090
Neurogenin2-d4Venus and Gadd45g-d4Venus transgenic mice: visualizing mitotic and migratory behaviors of cells committed to the neuronal lineage in the developing mammalian brainQ41899163
Rheb1 mediates DISC1-dependent regulation of new neuron development in the adult hippocampusQ42380993
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.Q43271908
Seizure-associated, aberrant neurogenesis in adult rats characterized with retrovirus-mediated cell labeling.Q44972977
Retrovirus-mediated single-cell gene knockout technique in adult newborn neurons in vivoQ46347673
Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus.Q46881337
P304page(s)261
P577publication date2017-08-29
P1433published inFrontiers in Cellular NeuroscienceQ2131509
P1476titleDISC1 Regulates the Proliferation and Migration of Mouse Neural Stem/Progenitor Cells through Pax5, Sox2, Dll1 and Neurog2.
P478volume11

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cites work (P2860)
Q58590857Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression
Q91995541Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication
Q89967573Parvalbumin Interneuron Activation-Dependent Adult Hippocampal Neurogenesis Is Required for Treadmill Running to Reverse Schizophrenia-Like Phenotypes
Q91892323Transplantation of mesenchymal stem cells causes long-term alleviation of schizophrenia-like behaviour coupled with increased neurogenesis