Communicative reprogramming non-curative hepatocellular carcinoma with low-dose metronomic chemotherapy, COX-2 inhibitor and PPAR-gamma agonist: a phase II trial.

scientific article published on 2 November 2017

Communicative reprogramming non-curative hepatocellular carcinoma with low-dose metronomic chemotherapy, COX-2 inhibitor and PPAR-gamma agonist: a phase II trial. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12032-017-1040-0
P932PMC publication ID5668342
P698PubMed publication ID29098441

P50authorAlbrecht ReichleQ59819086
P2093author name stringU Schulz
R Andreesen
F Klebl
W Herr
R Wiest
I Walter
L Ghibelli
E Endlicher
C Hackl
M Vogelhuber
K Wiedmann
P2860cites workGlobal cancer statistics, 2012Q27860501
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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion SequencingQ27860948
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Prognostic significance of cyclooxygenase-2 expression in patients with hepatocellular carcinoma: a meta-analysisQ28067391
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Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cellsQ33284848
Rosiglitazone sensitizes hepatocellular carcinoma cell lines to 5-fluorouracil antitumor activity through activation of the PPARgamma signaling pathwayQ33554975
Synergistic anti-tumor efficacy of sorafenib and fluvastatin in hepatocellular carcinomaQ33618658
Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN.Q33688897
Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway.Q34483561
Activation of peroxisome proliferator-activated receptor-γ (PPARγ) inhibits hepatoma cell growth via downregulation of SEPT2 expressionQ35543448
PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice.Q35927161
Serum C-reactive protein levels predict survival in hepatocellular carcinomaQ81226961
Peroxisome proliferator-activated receptor gamma inhibits hepatic fibrosis in ratsQ83304890
Hepatocellular carcinoma with extrahepatic metastasis: clinical features and prognostic factorsQ83710870
Management of hand-foot syndrome induced by capecitabineQ36615314
Prognostic role of C-reactive protein in hepatocellular carcinoma: a systematic review and meta-analysisQ36746912
Cyclooxygenase-2 (COX-2)--a therapeutic target in liver cancer?Q37018002
Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinomaQ37031730
Design and endpoints of clinical trials in hepatocellular carcinoma.Q37162908
Peroxisome Proliferator-Activated Receptor γ Expression Is Inversely Associated with Macroscopic Vascular Invasion in Human Hepatocellular Carcinoma.Q37209921
Metronomic chemotherapy: possible clinical application in advanced hepatocellular carcinomaQ37236004
Prognostic indicators in hepatocellular carcinoma: a systematic review of 72 studiesQ37263149
Metronomic capecitabine in advanced hepatocellular carcinoma patients: a phase II studyQ37404372
Antiangiogenic treatment in hepatocellular carcinoma: the balance of efficacy and safetyQ38160838
Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cellsQ38306392
CITED2 is a novel direct effector of peroxisome proliferator-activated receptor γ in suppressing hepatocellular carcinoma cell growthQ38319523
Systemic treatment for hepatocellular carcinoma: Still unmet expectationsQ39112745
Immune Checkpoint Inhibition in Hepatocellular Carcinoma: Basics and Ongoing Clinical TrialsQ39113725
Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro.Q39698351
Cellular and molecular effects of metronomic vinorelbine and 4-O-deacetylvinorelbine on human umbilical vein endothelial cellsQ40249987
Metronomic low-dose chemotherapy boosts CD95-dependent antiangiogenic effect of the thrombospondin peptide ABT-510: a complementation antiangiogenic strategy.Q40372701
Expression of peroxisome proliferator-activated receptor delta in human gastric cancer and its response to specific COX-2 inhibitor.Q40423550
Anakoinosis: Communicative Reprogramming of Tumor Systems - for Rescuing from Chemorefractory NeoplasiaQ40640442
MiR-429 increases the metastatic capability of HCC via regulating classic Wnt pathway rather than epithelial-mesenchymal transitionQ40990148
Effect of pioglitazone on outcome following curative treatment for hepatocellular carcinoma in patients with hepatitis C virus infection: A prospective studyQ41621514
Systems biology: a therapeutic target for tumor therapyQ41961938
Principles of modular tumor therapyQ42053204
C-reactive Protein in Patients with Metastatic Clear Cell Renal Carcinoma: An Important Biomarker for Tumor-associated InflammationQ42590411
Survival for haematological malignancies in Europe between 1997 and 2008 by region and age: results of EUROCARE-5, a population-based studyQ43938501
Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells.Q44656367
Tumor size of hepatocellular carcinoma in noncirrhotic liver: a controversial predictive factor for outcome after resection.Q47293605
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P921main subjectphase II clinical trialQ42824440
P304page(s)192
P577publication date2017-11-02
P1433published inMedical OncologyQ2152666
P1476titleCommunicative reprogramming non-curative hepatocellular carcinoma with low-dose metronomic chemotherapy, COX-2 inhibitor and PPAR-gamma agonist: a phase II trial
P478volume34

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cites work (P2860)
Q64118821A Computational Model of Tumor Growth and Anakoinosis
Q92541944Anakoinosis: Correcting Aberrant Homeostasis of Cancer Tissue-Going Beyond Apoptosis Induction
Q59805381Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis
Q64070822Exosomes and Hepatocellular Carcinoma: From Bench to Bedside
Q59335637Lowering Etoposide Doses Shifts Cell Demise From Caspase-Dependent to Differentiation and Caspase-3-Independent Apoptosis via DNA Damage Response, Inducing AML Culture Extinction
Q59793687Peroxisome Proliferator-Activated Receptors (PPAR)γ Agonists as Master Modulators of Tumor Tissue

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