Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic

scientific article published on 20 December 2017

Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41598-017-18106-2
P932PMC publication ID5738413
P698PubMed publication ID29263343

P50authorKate L OrmerodQ56952570
Milos TanurdzicQ56983449
Benjamin L SchulzQ42388929
P2093author name stringJames A Fraser
Samantha D M Arras
Monica I Espinosa
Paige E Erpf
Ross D Blundell
Alex C Carpenter
Samantha R Stowasser
P2860cites workSgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylationQ24306793
Fast and accurate short read alignment with Burrows-Wheeler transformQ24653853
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivatorQ27619265
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing dataQ27860742
The language of covalent histone modificationsQ27860931
The Sequence Alignment/Map format and SAMtoolsQ27860966
Sgf29p facilitates the recruitment of TATA box binding protein but does not alter SAGA's global structural integrity in vivoQ27930044
Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometryQ27931371
Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexesQ27932566
The N-terminus and Tudor domains of Sgf29 are important for its heterochromatin boundary formation functionQ27935220
Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activationQ27937778
Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus neoformansQ28554238
A framework for variation discovery and genotyping using next-generation DNA sequencing dataQ29547262
Trimmomatic: a flexible trimmer for Illumina sequence dataQ29547278
BEDTools: a flexible suite of utilities for comparing genomic featuresQ29547332
Histone acetyltransferase complexes: one size doesn't fit allQ29620006
Insertion sequence-related genetic variation in resting Escherichia coli K-12.Q30011213
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuationQ30457891
Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformansQ33587342
The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosisQ33691482
Distinct and redundant roles of protein tyrosine phosphatases Ptp1 and Ptp2 in governing the differentiation and pathogenicity of Cryptococcus neoformansQ33743558
Microevolution of a standard strain of Cryptococcus neoformans resulting in differences in virulence and other phenotypes.Q33747538
Estimate of the genomic mutation rate deleterious to overall fitness in E. coliQ51030744
Microevolution of Cryptococcus neoformans Driven by Massive Tandem Gene AmplificationQ58206381
Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformansQ33768483
Urease as a virulence factor in experimental cryptococcosisQ33886908
The population genetics of ecological specialization in evolving Escherichia coli populationsQ33922714
Hunger artists: yeast adapted to carbon limitation show trade-offs under carbon sufficiencyQ33987589
Timing of antiretroviral therapy after diagnosis of cryptococcal meningitisQ34024416
Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the hostQ34055174
Toward an integrated model of capsule regulation in Cryptococcus neoformansQ34102709
Whole genome, whole population sequencing reveals that loss of signaling networks is the major adaptive strategy in a constant environmentQ34387997
A dual role for SAGA-associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylationQ34875163
BreakDancer: an algorithm for high-resolution mapping of genomic structural variationQ34996567
Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the hostQ35032086
A genomic safe haven for mutant complementation in Cryptococcus neoformansQ35347470
A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulenceQ35826981
Physiological studies of Escherichia coli strain MG1655: growth defects and apparent cross-regulation of gene expressionQ35921898
Stock culture heterogeneity rather than new mutational variation complicates short-term cell physiology studies of Escherichia coli K-12 MG1655 in continuous culture.Q35959844
CREST maps somatic structural variation in cancer genomes with base-pair resolution.Q36480006
Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformansQ37066510
The impact of routine cryptococcal antigen screening on survival among HIV-infected individuals with advanced immunosuppression in KenyaQ37259604
Role of ferric reductases in iron acquisition and virulence in the fungal pathogen Cryptococcus neoformansQ37546412
Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomesQ37579943
Cryptococcosis: a model for the understanding of infectious diseasesQ37726691
Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, CanadaQ39011044
Storage of stock cultures of filamentous fungi, yeasts, and some aerobic actinomycetes in sterile distilled waterQ39861112
Karyotype instability in Cryptococcus neoformans infectionQ40010933
Pigment production by Cryptococcus neoformans from para- and ortho-Diphenols: effect of the nitrogen sourceQ40238982
Long-term preservation of fungal isolates in commercially prepared cryogenic microbank vials.Q40638423
Titan cell production enhances the virulence of Cryptococcus neoformans.Q41585131
Rapid and spontaneous loss of phthiocerol dimycocerosate (PDIM) from Mycobacterium tuberculosis grown in vitro: implications for virulence studiesQ41909471
Burkholderia pseudomallei virulence: definition, stability and association with clonality.Q43668301
Cryptococcosis in Australasia and the treatment of cryptococcal and other fungal infections with liposomal amphotericin B.Q43860674
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectCryptococcus neoformansQ131924
microevolutionQ680054
P304page(s)17918
P577publication date2017-12-20
P1433published inScientific ReportsQ2261792
P1476titleConvergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
P478volume7

Reverse relations

cites work (P2860)
Q64229904Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis
Q92482193Intranasal Inoculation of Cryptococcus neoformans in Mice Produces Nasal Infection with Rapid Brain Dissemination
Q55032452Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators.
Q50158602Unintended Side Effects of Transformation Are Very Rare in Cryptococcus neoformans.

Search more.