Aptamer Bioinformatics

scientific article published on 24 November 2017

Aptamer Bioinformatics is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3390/IJMS18122516
P932PMC publication ID5751119
P698PubMed publication ID29186809

P50authorLewis A. FraserQ47175004
Simon Chi-Chin ShiuQ47175010
Julian A. TannerQ45891244
P2093author name stringAndrew B Kinghorn
Shaolin Lang
P2860cites workTime-dependent extinction rate and species abundance in a tangled-nature model of biological evolutionQ48729262
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesisQ24313372
Mfold web server for nucleic acid folding and hybridization predictionQ24498105
Sfold web server for statistical folding and rational design of nucleic acidsQ24562042
Automated 3D structure composition for large RNAsQ24622388
Genomic SELEX for Hfq-binding RNAs identifies genomic aptamers predominantly in antisense transcriptsQ24633132
Automated de novo prediction of native-like RNA tertiary structuresQ24673712
Abundance of correctly folded RNA motifs in sequence space, calculated on computational gridsQ24813759
2.8 A crystal structure of the malachite green aptamerQ27625739
Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamerQ27679972
Structural basis for activity of highly efficient RNA mimics of green fluorescent proteinQ27684699
Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genomeQ27710266
All-atom empirical potential for molecular modeling and dynamics studies of proteinsQ27860468
The SWISS-MODEL workspace: a web-based environment for protein structure homology modellingQ27860637
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymeraseQ27860794
In vitro selection of RNA molecules that bind specific ligandsQ27861109
Applications of High-Throughput Sequencing for In Vitro Selection and Characterization of AptamersQ28071419
Inferring binding energies from selected binding sitesQ28472054
Influence of target concentration and background binding on in vitro selection of affinity reagentsQ28482831
Galaxy Workflows for Web-based Bioinformatics Analysis of Aptamer High-throughput Sequencing DataQ28595781
Aptamer Base: a collaborative knowledge base to describe aptamers and SELEX experimentsQ28731215
Probing the SELEX process with next-generation sequencingQ28740666
Aptamers Selected for Higher-Affinity Binding Are Not More Specific for the Target LigandQ29038329
The Phyre2 web portal for protein modeling, prediction and analysisQ29616136
DOVIS: an implementation for high-throughput virtual screening using AutoDockQ30481462
Screening and Identification of DNA Aptamers to Tyramine Using in Vitro Selection and High-Throughput Sequencing.Q50863226
In Silico Aptamer Docking Studies: From a Retrospective Validation to a Prospective Case Study-TIM3 Aptamers Binding.Q51380809
GROMACS: A message-passing parallel molecular dynamics implementationQ51756282
In silico modelling of directed evolution: Implications for experimental design and stepwise evolution.Q51860397
ZDOCK: an initial-stage protein-docking algorithm.Q52015255
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.Q55476886
The crystal and molecular structure of a hydrogen-bonded complex between 1-methylthymine and 9-methyladenineQ57534974
Selective Phenome Growth Adapted NK Model: A Novel Landscape to Represent Aptamer Ligand BindingQ59142935
AptaCluster - A Method to Cluster HT-SELEX Aptamer Pools and Lessons from its ApplicationQ60175393
Pore Formation Coupled to Ion Transport through Lipid Membranes as Induced by Transmembrane Ionic Charge Imbalance: Atomistic Molecular Dynamics StudyQ61875087
Sequence space localization in the immune system response to vaccination and diseaseQ73844607
Theory and applications of the generalized Born solvation model in macromolecular simulationsQ77381573
Quadruplex-based molecular beacons as tunable DNA probesQ80151687
SELEX: just another separation?Q81308700
Geometric formalism for DNA quadruplex foldingQ81525622
Structural basis for high-affinity fluorophore binding and activation by RNA MangoQ47132440
Towards a general theory of adaptive walks on rugged landscapesQ47593883
Protein-DNA docking with a coarse-grained force fieldQ30529906
Isolation of high-affinity GTP aptamers from partially structured RNA librariesQ30843685
AptaGUI-A Graphical User Interface for the Efficient Analysis of HT-SELEX DataQ31004700
Analyzing HT-SELEX data with the Galaxy Project tools--A web based bioinformatics platform for biomedical research.Q31007883
The mathematics of SELEX against complex targetsQ32062858
Subtractive SELEX against two heterogeneous target samples: numerical simulations and analysisQ33254511
Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamerQ33303295
Exploring the sequence space of a DNA aptamer using microarraysQ33304953
Theoretical principles of in vitro selection using combinatorial nucleic acid librariesQ33329973
A new method to compute K-mer frequencies and its application to annotate large repetitive plant genomesQ33381864
3D-DART: a DNA structure modelling serverQ33439390
In silico selection of RNA aptamersQ33451579
Monitoring genomic sequences during SELEX using high-throughput sequencing: neutral SELEX.Q33531798
Telomeres and telomerase: from discovery to clinical trialsQ33607376
Enhanced functional potential of nucleic acid aptamer libraries patterned to increase secondary structureQ33610517
Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencingQ33655937
Sequencing your genome: what does it mean?Q33732868
Particle display: a quantitative screening method for generating high-affinity aptamers.Q33786340
SELEXION. Systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysisQ34001832
Molecular dynamics simulations and drug discoveryQ34061019
Aptamer selection by high-throughput sequencing and informatic analysisQ34093799
Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing.Q34204137
Triplex DNA structures.Q34296747
Microfluidic approaches to rapid and efficient aptamer selectionQ34303936
Informational complexity and functional activity of RNA structuresQ34315065
In vitro RNA random pools are not structurally diverse: a computational analysisQ34366408
Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selectionQ34409758
Structure clustering features on the Sfold Web serverQ34444156
Coming of age: ten years of next-generation sequencing technologiesQ34526801
Controlling uncertainty in aptamer selectionQ34543607
Assessing the amount of quadruplex structures present within G₂-tract synthetic random-sequence DNA librariesQ34745287
Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2Q34981750
Tracking the emergence of high affinity aptamers for rhVEGF165 during capillary electrophoresis-systematic evolution of ligands by exponential enrichment using high throughput sequencingQ35017397
FASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections.Q35161360
Computational selection of RNA aptamer against angiopoietin-2 and experimental evaluationQ35250485
Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discoveryQ35600644
More DNA-Aptamers for Small Drugs: A Capture-SELEX Coupled with Surface Plasmon Resonance and High-Throughput SequencingQ35601850
Single-Round Patterned DNA Library Microarray Aptamer Lead IdentificationQ35657036
Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools.Q35688562
Analysis of In Vitro Aptamer Selection ParametersQ35830915
AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX ExperimentsQ36088479
High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency.Q36139325
Aptamer Selection Technology and Recent AdvancesQ36256736
Evolution of Complex Target SELEX to Identify Aptamers against Mammalian Cell-Surface AntigensQ36266158
Identification of a new class of exonic splicing enhancers by in vivo selectionQ36567695
High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptaseQ36580881
A novel protocol for three-dimensional structure prediction of RNA-protein complexesQ36878829
Molecular dynamics simulations of nucleic acid-protein complexes.Q37087008
A computationally designed DNA aptamer template with specific binding to phosphatidylserineQ37403863
Selection of DNA Aptamers for Ovarian Cancer Biomarker CA125 Using One-Pot SELEX and High-Throughput SequencingQ37661390
RNA and DNA complexes with hemin [Fe(III) heme] are efficient peroxidases and peroxygenases: how do they do it and what does it mean?Q37940577
Complex SELEX against target mixture: stochastic computer model, simulation, and analysisQ38300116
Affinity improvement of a VEGF aptamer by in silico maturation for a sensitive VEGF-detection system.Q38319303
Antiproliferative activity of G-rich oligonucleotides correlates with protein bindingQ38320934
Combinatorial selection of high affinity RNA ligands to live African trypanosomesQ38326105
DNA-enhanced peroxidase activity of a DNA-aptamer-hemin complexQ38333033
Entropic fragment-based approach to aptamer designQ38335871
Analysis of aptamer sequence activity relationshipsQ38347807
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscapeQ38358691
Advancements in Aptamer Discovery TechnologiesQ39488994
Aptamer Affinity Maturation by Resampling and Microarray Selection.Q39653640
Global similarities in nucleotide base composition among disparate functional classes of single-stranded RNA imply adaptive evolutionary convergenceQ41779444
RazerS--fast read mapping with sensitivity controlQ42566501
Convergent evolution to an aptamer observed in small populations on DNA microarraysQ42920087
Enzyme-free unlabeled DNA logic circuits based on toehold-mediated strand displacement and split G-quadruplex enhanced fluorescence.Q44051105
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectbioinformaticsQ128570
nucleotideQ28745
computational biologyQ177005
nucleotide aptamersQ49849144
biomedical investigative techniqueQ66648976
P577publication date2017-11-24
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleAptamer Bioinformatics
P478volume18

Reverse relations

cites work (P2860)
Q90460561A Bottom-Up Approach for Developing Aptasensors for Abused Drugs: Biosensors in Forensics
Q92354221Detection of Nonylphenol with a Gold-Nanoparticle-Based Small-Molecule Sensing System Using an ssDNA Aptamer
Q90497112Digitizable therapeutics for decentralized mitigation of global pandemics
Q90296614In Silico Selection Approach to Develop DNA Aptamers for a Stem-like Cell Subpopulation of Non-small Lung Cancer Adenocarcinoma Cell Line A549
Q93131357Integrating Ligand-Receptor Interactions and In Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands
Q58700124Molecular Modeling Applied to Nucleic Acid-Based Molecule Development
Q91973459Predicting the Most Stable Aptamer/Target Molecule Complex Configuration Using a Stochastic-Tunnelling Basin-Hopping Discrete Molecular Dynamics Method: A Novel Global Minimum Search Method for a Biomolecule Complex
Q51150222Refining the Results of a Classical SELEX Experiment by Expanding the Sequence Data Set of an Aptamer Pool Selected for Protein A.
Q52362632Selection and Characterization of a DNA Aptamer Specifically Targeting Human HECT Ubiquitin Ligase WWP1.
Q89621518Selection and characterization of single-stranded DNA aptamers against interleukin-5
Q93075081TNBC Challenge: Oligonucleotide Aptamers for New Imaging and Therapy Modalities

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