Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase.

scientific article published on 25 December 2017

Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS19010053
P932PMC publication ID5796003
P698PubMed publication ID29295567

P50authorJung-Ae KimQ87859352
Ohsang S. KwonQ55233986
P2093author name stringSoohwan Yum
Do Sik Min
Wooseong Kim
Dae-Duk Kim
Sunyoung Lee
Jin-Wook Yoo
Seongkeun Jeong
Yunjin Jung
Dohoon Kim
P2860cites workHIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensingQ24291102
A conserved family of prolyl-4-hydroxylases that modify HIFQ24291794
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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor proteinQ24599442
Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathwayQ24672316
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylationQ27860876
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Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor proteinQ29615931
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stabilityQ29615945
Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changesQ29617594
Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activityQ33224552
Hypertrichosis due to diazoxideQ34526758
Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunitQ34661126
Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acidQ34760312
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Topical minoxidil in the treatment of alopecia areata.Q34995789
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Control of hair growth and follicle size by VEGF-mediated angiogenesisQ36011340
Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer.Q37184870
Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factorsQ37639838
Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidilQ38291353
Piceatannol, a hydroxystilbene natural product, stabilizes HIF-1α protein by inhibiting HIF prolyl hydroxylaseQ39221944
Hair follicle biology and topical minoxidil: possible mechanisms of actionQ39685773
Troglitazone inhibits vascular endothelial growth factor-induced angiogenic signaling via suppression of reactive oxygen species production and extracellular signal-regulated kinase phosphorylation in endothelial cellsQ43274985
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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathwayQ44019897
Microtubule disruption utilizes an NFkappa B-dependent pathway to stabilize HIF-1alpha proteinQ44253539
Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicleQ44806656
Promotion effect of Schisandra nigra on the growth of hairQ46157439
Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthmaQ46734329
Vascular patterns associated with categen hair follicles in the human scalpQ79224455
Minoxidil activates β-catenin pathway in human dermal papilla cells: a possible explanation for its anagen prolongation effectQ83983473
Loss of vascular endothelial growth factor in human alopecia hair folliclesQ49168794
Quercetin activates an angiogenic pathway, hypoxia inducible factor (HIF)-1-vascular endothelial growth factor, by inhibiting HIF-prolyl hydroxylase: a structural analysis of quercetin for inhibiting HIF-prolyl hydroxylase.Q53575002
Drug and vehicle deposition from topical applications: use of in vitro mass balance technique with minoxidil solutionsQ67559231
Topical minoxidil in the treatment of androgenetic alopecia in womenQ68034627
Minoxidil sulfate is the active metabolite that stimulates hair folliclesQ68587443
Minoxidil stimulates mouse vibrissae follicles in organ cultureQ69054553
Topical minoxidil therapy and hair regrowthQ70068483
The culture of dermal papilla cells from human hair folliclesQ70360915
Drug and vehicle deposition from topical applications: localization of minoxidil within skin strata of the hairless mouseQ72115249
Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cellsQ74528277
Expression of vascular endothelial growth factor (VEGF) in various compartments of the human hair follicleQ77763903
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P577publication date2017-12-25
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleMinoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase
P478volume19