FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway.

scientific article published in July 2004

FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1097/01.SLA.0000129673.13552.C0
P932PMC publication ID1356388
P698PubMed publication ID15213632
P5875ResearchGate publication ID8493874

P50authorKevin Tak-Pan NgQ57044165
Terence Kin-Wah LeeQ73885432
P2093author name stringChung Mau Lo
Sheung Tat Fan
Kwan Man
Ting Bo Liang
Xian Liang Li
Peter Chin-Wan Fung
Steven H Tsui
P2860cites workA20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cellsQ24304048
Inducible nitric oxide synthase is critical for immune-mediated liver injury in miceQ28350110
Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stressQ28512203
Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core proteinQ29620682
Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expressionQ31128465
A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitisQ33183441
Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout miceQ33749161
Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injuryQ33902524
Hsp70 chaperone systems: diversity of cellular functions and mechanism of actionQ41752367
Nitric oxide inhibits endothelin-1 production through the suppression of nuclear factor kappa B.Q42525112
Macrophage inflammatory protein-2 induced by TNF-alpha plays a pivotal role in concanavalin A-induced liver injury in miceQ43753013
IFN-gamma-inducible protein-10 (CXCL10) is hepatoprotective during acute liver injury through the induction of CXCR2 on hepatocytesQ43819919
Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylationQ43933105
Blockade of the L-arginine/NO synthase pathway worsens hepatic apoptosis and liver transplant preservation injuryQ44116617
Liver transplantation in rats using small-for-size grafts: a study of hemodynamic and morphological changesQ47216526
FK409 inhibits both local and remote organ damage after intestinal ischaemia.Q49051660
Intragraft gene expression profiles by cDNA microarray in small-for-size liver grafts.Q52550074
Endothelin-1 modulates intrahepatic resistance in a rat model of noncirrhotic portal hypertension.Q54085349
Endothelin-1 selectively contracts portal vein through both ETA and ETB receptors in isolated rabbit liver.Q54151742
Endothelin-1 is involved in the pathogenesis of ischemia/reperfusion liver injury by hepatic microcirculatory disturbancesQ72271861
Endothelin-1 induces direct constriction of hepatic sinusoidsQ72411025
Distinct intragraft response pattern in relation to graft size in liver transplantationQ73134616
Cardioprotective effects of FK409, a nitric oxide donor, after isolated rat heart preservation for 16 hoursQ73228911
A protective player in the vascular response to injuryQ73954816
Prior induction of heat shock proteins by a nitric oxide donor attenuates cardiac ischemia/reperfusion injury in the ratQ74052942
Plasma nitric oxide is associated with the occurrence of moderate to severe acute graft-versus-host disease in haemopoietic stem cell transplant recipientsQ74452983
Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantationQ74629369
Extinguishing Egr-1-dependent inflammatory and thrombotic cascades after lung transplantationQ74631235
Beneficial effects of FK409, a novel nitric oxide donor, on reperfusion injury of rat liverQ77349298
Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: implications of a central role for nuclear factor kappaBQ77933566
Nitric oxide regulates shear stress-induced early growth response-1. Expression via the extracellular signal-regulated kinase pathway in endothelial cellsQ78095132
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectportal hypertensionQ124604
P304page(s)159-168
P577publication date2004-07-01
P1433published inAnnals of SurgeryQ4767866
P1476titleFK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway
P478volume240

Reverse relations

cites work (P2860)
Q47371153A better way to do small-for-size liver transplantation in rats
Q35786350Acute milk yield response to frequent milking during early lactation is mediated by genes transiently regulated by milk removal
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Q45214556FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers.
Q46936581Fat-derived hormone adiponectin combined with FTY720 significantly improves small-for-size fatty liver graft survival.
Q47114724Glutathione Peroxidase 3 Delivered by hiPSC-MSCs Ameliorated Hepatic IR Injury via Inhibition of Hepatic Senescence
Q50458205Hepatoprotective effect by pretreatment with olprinone in a swine partial hepatectomy model
Q40136744Historical perspective of living donor liver transplantation
Q47295442Impact of Splenectomy Just Before Partial Orthotopic Liver Transplantation Using Small-for-Size Graft in Rats
Q41388931Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viability
Q47339438Implanted adipose-derived stem cells attenuate small-for-size liver graft injury by secretion of VEGF in rats
Q43141419Inhibition of inducible nitric oxide synthase worsens liver damage regardless of lipopolysaccharide treatment in small-for-size liver transplantation
Q43666531Initial clinical effect of intraportal insulin administration on liver graft regeneration in adult patients underwent living donor right lobe liver transplantation
Q51028343Losartan supports liver regrowth via distinct boost of portal vein pressure in rodents with 90 % portal branch ligation.
Q28565948N-n-butyl haloperidol iodide protects cardiac microvascular endothelial cells from hypoxia/reoxygenation injury by down-regulating Egr-1 expression
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Q84943474Small liver remnants are more vulnerable to ischemia/reperfusion injury after extended hepatectomies: a case-control study
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Q36280426Small-for-size syndrome after partial liver transplantation: definition, mechanisms of disease and clinical implications
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Q37982411The nitric oxide pathway--evidence and mechanisms for protection against liver ischaemia reperfusion injury

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