Tm-Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions.

scientific article published on 15 November 2017

Tm-Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/ACS.MOLPHARMACEUT.7B00876
P698PubMed publication ID29141152

P50authorPaul A DalbyQ54358055
Paul MatejtschukQ58879653
P2093author name stringAdrian F Bristow
Mathew J Robinson
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)256-267
P577publication date2017-11-28
P1433published inMolecular PharmaceuticsQ3011140
P1476titleTm-Values and Unfolded Fraction Can Predict Aggregation Rates for Granulocyte Colony Stimulating Factor Variant Formulations but Not under Predominantly Native Conditions
P478volume15

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cites work (P2860)
Q91693962An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations
Q58602191Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics
Q60907178Exploiting correlated molecular-dynamics networks to counteract enzyme activity-stability trade-off
Q90476000Formulations That Suppress Aggregation During Long-Term Storage of a Bispecific Antibody are Characterized by High Refoldability and Colloidal Stability
Q57049370Quality Comparison of Biosimilar and Copy Filgrastim Products with the Innovator Product
Q104064437Stability enhancement in a mAb and Fab coformulation

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