Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy.

scientific article published on 26 August 2016

Restoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/GERONA/GLW168
P698PubMed publication ID27565512

P50authorLi MaQ60997850
P2093author name stringQiang Wang
Jiang Zhu
Qun Gao
Lixin Liu
Mario J Rebecchi
P2860cites workRedox balance and cardioprotection.Q38155452
Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranesQ39532979
Tempol reduces infarct size in rodent models of regional myocardial ischemia and reperfusionQ40928505
Mechanisms of isoflurane-induced myocardial preconditioning in rabbitsQ41613712
Autophagy is required for preconditioning by the adenosine A1 receptor-selective agonist CCPA.Q42032448
Age-associated differences in activation of Akt/GSK-3beta signaling pathways and inhibition of mitochondrial permeability transition pore opening in the rat heartQ43081782
Suppression of phosphoinositide 3-kinase prevents cardiac aging in miceQ43263000
Interactions of GSK-3β with mitochondrial permeability transition pore modulators during preconditioning: age-associated differencesQ44576982
Comparison of isoflurane-, sevoflurane-, and desflurane-induced pre- and postconditioning against myocardial infarction in mice in vivo.Q45930174
Long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in ratsQ46170342
Attenuation of isoflurane-induced preconditioning and reactive oxygen species production in the senescent rat heartQ46421636
Antihypertensive response to prolonged tempol in the spontaneously hypertensive rat.Q46545489
Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivoQ46910238
Isoflurane preconditioning uncouples mitochondria and protects against hypoxia-reoxygenationQ48630672
Chronic Tempol treatment restores pharmacological preconditioning in the senescent rat heart.Q51840631
Cardioprotection of the aged rat heart by GSK-3beta inhibitor is attenuated: age-related changes in mitochondrial permeability transition pore modulation.Q54621362
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent mannerQ57245842
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcriptionQ24310885
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Mitochondrial reactive oxygen species: a double edged sword in ischemia/reperfusion vs preconditioningQ26861219
Mending a broken heart: the role of mitophagy in cardioprotectionQ26991630
Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote conditioningQ26995004
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Mitochondria and cell death: outer membrane permeabilization and beyondQ29615459
Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cellsQ30496731
Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.Q33936625
Mitochondrial depolarization underlies delay in permeability transition by preconditioning with isoflurane: roles of ROS and Ca2+.Q34085718
Mitophagy is required for acute cardioprotection by simvastatinQ34399751
Autophagy and mitophagy in diabetic cardiomyopathyQ34422305
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Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.Q34701379
Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy.Q35013816
Isoflurane reduces hypoxia/reoxygenation-induced apoptosis and mitochondrial permeability transition in rat primary cultured cardiocytesQ35115714
This old heart: Cardiac aging and autophagyQ35696206
Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioningQ35915777
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarctionQ36526385
Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen speciesQ36582810
Complex I and ATP synthase mediate membrane depolarization and matrix acidification by isoflurane in mitochondriaQ36842276
Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stressQ37057581
Age-related attenuation of isoflurane preconditioning in human atrial cardiomyocytes: roles for mitochondrial respiration and sarcolemmal adenosine triphosphate-sensitive potassium channel activityQ37230050
Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatmentQ37283952
Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 proteinQ37296016
Comparison of inhibitors of superoxide generation in vascular smooth muscle cellsQ37332631
Loss of cardioprotection with ageing.Q37379567
Autophagy: from basic science to clinical applicationQ37472903
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)489-498
P577publication date2017-04-01
P1433published inThe Journals of GerontologyQ7743644
P1476titleRestoring Pharmacologic Preconditioning in the Aging Heart: Role of Mitophagy/Autophagy
P478volume72

Reverse relations

cites work (P2860)
Q47730474Effect of Aging on Mitochondrial Energetics in the Human Atria
Q51760289Effects of volatile anesthetic preconditioning on expression of NFkB-regulated genes in aged rat myocardium.
Q90011780MCU Up-regulation contributes to myocardial ischemia-reperfusion Injury through calpain/OPA-1-mediated mitochondrial fusion/mitophagy Inhibition
Q90663952Mitophagy in Cardiovascular Diseases
Q39210684Myocardial stress and autophagy: mechanisms and potential therapies.
Q91646707Role of Mitophagy in Cardiovascular Disease
Q39363477The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection

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