| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.YGENO.2003.12.016 |
| P698 | PubMed publication ID | 15177551 |
| P2093 | author name string | Tong Xi | |
| Harvey W Mohrenweiser | |||
| Irene M Jones | |||
| P2860 | cites work | Predicting deleterious amino acid substitutions | Q22065761 |
| MULTIFACTORIAL GENETICSUNDERSTANDING QUANTITATIVE GENETIC VARIATION | Q22121996 | ||
| Searching for genetic determinants in the new millennium | Q22337300 | ||
| Cloning of CYP2J2 gene and identification of functional polymorphisms | Q24292485 | ||
| Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1 | Q24675093 | ||
| Characterization of single-nucleotide polymorphisms in coding regions of human genes | Q28138557 | ||
| Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis | Q28138570 | ||
| Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC) | Q28202312 | ||
| A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms | Q28203288 | ||
| Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans | Q28209488 | ||
| Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8 | Q28214230 | ||
| Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function | Q28216097 | ||
| A quantitative model of human DNA base excision repair. I. Mechanistic insights | Q28646701 | ||
| SIFT: Predicting amino acid changes that affect protein function | Q29547211 | ||
| The future of genetic studies of complex human diseases | Q29547215 | ||
| Human non-synonymous SNPs: server and survey | Q29547603 | ||
| Prediction of deleterious human alleles | Q29614367 | ||
| Amino acid difference formula to help explain protein evolution | Q29614440 | ||
| On the allelic spectrum of human disease | Q29616298 | ||
| SNPs, protein structure, and disease. | Q30328103 | ||
| Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties. | Q30329486 | ||
| A fast method for predicting amino acid mutations that lead to unfolding. | Q30704432 | ||
| Catalog of 434 single-nucleotide polymorphisms (SNPs) in genes of the alcohol dehydrogenase, glutathione S-transferase, and nicotinamide adenine dinucleotide, reduced (NADH) ubiquinone oxidoreductase families | Q30994754 | ||
| Functional characterization of Ape1 variants identified in the human population | Q33786876 | ||
| Towards a structural basis of human non-synonymous single nucleotide polymorphisms | Q33899435 | ||
| Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review | Q33936434 | ||
| DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis | Q34132208 | ||
| Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes. | Q34158588 | ||
| BRCA1 and BRCA2 and the genetics of breast and ovarian cancer | Q34189009 | ||
| Mining for SNPs: putting the common variants--common disease hypothesis to the test | Q34189877 | ||
| Understanding missense mutations in the BRCA1 gene: an evolutionary approach | Q34329529 | ||
| Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer? | Q34390257 | ||
| Patterns of genetic variation in Mendelian and complex traits | Q34433408 | ||
| Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases | Q34667722 | ||
| Beyond Mendel: an evolving view of human genetic disease transmission | Q34932051 | ||
| Natural variation in human membrane transporter genes reveals evolutionary and functional constraints | Q35022362 | ||
| A polygenic basis for late-onset disease | Q35053431 | ||
| Repair mechanisms for oxidative DNA damage | Q35109446 | ||
| Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes | Q35114513 | ||
| From genotype to phenotype: correlating XRCC1 polymorphisms with mutagen sensitivity | Q38351985 | ||
| Inherited susceptibility to bleomycin-induced chromatid breaks in cultured peripheral blood lymphocytes | Q39118556 | ||
| Accounting for human polymorphisms predicted to affect protein function | Q39753550 | ||
| Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation | Q40718968 | ||
| Sequence diversity in 36 candidate genes for cardiovascular disorders | Q41993571 | ||
| Understanding human disease mutations through the use of interspecific genetic variation | Q43572665 | ||
| Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes | Q43901533 | ||
| Effect of DNA repair gene polymorphisms on BPDE-DNA adducts in human lymphocytes | Q44062575 | ||
| Identification and functional characterization of new potentially defective alleles of human CYP2C19. | Q44237764 | ||
| Gene and protein domain-specific patterns of genetic variability within the G-protein coupled receptor superfamily | Q44299521 | ||
| Polymorphisms in human soluble epoxide hydrolase. | Q44517651 | ||
| Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups | Q44534413 | ||
| Identification of 187 single nucleotide polymorphisms (SNPs) among 41 candidate genes for ischemic heart disease in the Japanese population | Q44934234 | ||
| A phylogenetic approach to assessing the significance of missense mutations in disease genes | Q47818899 | ||
| Structural location of disease-associated single-nucleotide polymorphisms | Q48008000 | ||
| DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene | Q48036374 | ||
| Evaluation of structural and evolutionary contributions to deleterious mutation prediction. | Q52032041 | ||
| The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis. | Q54089902 | ||
| Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III. | Q54549820 | ||
| A DNA Polymorphism Discovery Resource for Research on Human Genetic Variation: Table 1 | Q56566320 | ||
| SNP frequencies in human genes | Q56918467 | ||
| Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population | Q57269482 | ||
| Amino acid substitutions in the human genome: evolutionary implications of single nucleotide polymorphisms. | Q64898209 | ||
| The new genomics: global views of biology | Q71798637 | ||
| Performance evaluation of amino acid substitution matrices | Q72589783 | ||
| Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease | Q73692904 | ||
| Predicting the structure of protein cavities created by mutation | Q78328411 | ||
| P433 | issue | 6 | |
| P921 | main subject | protein function prediction | Q7251473 |
| P304 | page(s) | 970-979 | |
| P577 | publication date | 2004-06-01 | |
| P1433 | published in | Genomics | Q5533503 |
| P1476 | title | Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function | |
| P478 | volume | 83 |
| Q41873773 | A Bayesian Hierarchical Model for Relating Multiple SNPs within Multiple Genes to Disease Risk |
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| Q34043116 | A mathematical model for DNA damage and repair |
| Q36843016 | A novel computational and structural analysis of nsSNPs in CFTR gene |
| Q46967363 | APE1 Asp148Glu gene polymorphism and bladder cancer risk: a meta-analysis |
| Q45752332 | APE1 Asp148Glu gene polymorphism and lung cancer risk: a meta-analysis |
| Q44498341 | Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR). |
| Q33933190 | An approach to identify SNPs in the gene encoding acetyl-CoA acetyltransferase-2 (ACAT-2) and their proposed role in metabolic processes in pig. |
| Q30380373 | Applications of computational tools to predict functional SNPs effects in human ErbB genes. |
| Q30426205 | Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hierarchical modeling |
| Q36710139 | Association between APE1 Asp148Glu polymorphism and the risk of urinary cancers: a meta-analysis of 18 case-control studies |
| Q37657335 | Association between APE1 Single Nucleotide Polymorphism (rs1760944) and Cancer Risk: a Meta-Analysis Based on 6,419 Cancer Cases and 6,781 Case-free Controls |
| Q31130184 | Association between XRCC1 and XRCC3 polymorphisms with lung cancer risk: a meta-analysis from case-control studies |
| Q91719044 | Association between apurinic/apyrimidinic endonuclease 1 rs1760944 T>G polymorphism and susceptibility of cancer: a meta-analysis involving 21764 subjects |
| Q36724366 | Association between polymorphisms of APE1 and OGG1 and risk of colorectal cancer in Taiwan |
| Q35265963 | Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial |
| Q53107746 | Association between the OGG1 Ser326Cys and APEX1 Asp148Glu polymorphisms and lung cancer risk: a meta-analysis. |
| Q35741204 | Assoication of XRCC1 gene polymorphisms with risk of non-small cell lung cancer |
| Q30438210 | Autosomal-dominant distal myopathy associated with a recurrent missense mutation in the gene encoding the nuclear matrix protein, matrin 3 |
| Q85051064 | Base excision repair genes XRCC1 and APEX1 and the risk for prostate cancer |
| Q21261231 | CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma |
| Q36801775 | Combined sequence and sequence-structure based methods for analyzing FGF23, CYP24A1 and VDR genes |
| Q51082681 | Combined sequence and sequence-structure-based methods for analyzing RAAS gene SNPs: a computational approach. |
| Q42971520 | Comparative analyses of the β-tubulin gene and molecular modeling reveal molecular insight into the colchicine resistance in kinetoplastids organisms |
| Q49075112 | Comprehensive NF1 screening on cultured Schwann cells from neurofibromas. |
| Q53144592 | Comprehensive assessment of the association between XPD rs13181 polymorphism and lung cancer risk. |
| Q45960056 | Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations. |
| Q55689889 | Computational methods to work as first-pass filter in deleterious SNP analysis of alkaptonuria. |
| Q36538480 | Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools |
| Q33881993 | DNA damage and nucleotide excision repair capacity in healthy individuals. |
| Q35821428 | Defining molecular and cellular responses after low and high linear energy transfer radiations to develop biomarkers of carcinogenic risk or therapeutic outcome |
| Q28755464 | Determinants of protein function revealed by combinatorial entropy optimization |
| Q57664773 | ERCC5 p.Asp1104His and ERCC2 p.Lys751Gln Polymorphisms Are Independent Prognostic Factors for the Clinical Course of Melanoma |
| Q34486518 | Effect of APE1 T2197G (Asp148Glu) polymorphism on APE1, XRCC1, PARP1 and OGG1 expression in patients with colorectal cancer. |
| Q64229538 | Effect of the thymine-DNA glycosylase rs4135050 variant on Saudi smoker population |
| Q24621116 | Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts |
| Q37321850 | Evaluation and identification of damaged single nucleotide polymorphisms in COL1A1 gene involved in osteoporosis. |
| Q21260419 | Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition |
| Q34085818 | FEN1 -69G>A and 4150G>T polymorphisms and cancer risk in Chinese population |
| Q34209183 | Ferroportin disease: a systematic meta-analysis of clinical and molecular findings |
| Q38978320 | Functional and Structural Consequences of Damaging Single Nucleotide Polymorphisms in Human Prostate Cancer Predisposition Gene RNASEL. |
| Q34776057 | Functional assessment of population and tumor-associated APE1 protein variants |
| Q33659502 | Functional evaluation of DNA repair in human biopsies and their relation to other cellular biomarkers |
| Q30416471 | Functional genomics based prioritization of potential nsSNPs in EPHX1, GSTT1, GSTM1 and GSTP1 genes for breast cancer susceptibility studies |
| Q36405312 | Functional nsSNPs from carcinogenesis-related genes expressed in breast tissue: potential breast cancer risk alleles and their distribution across human populations |
| Q87623401 | Genetic polymorphism of APE1 rs1130409 can contribute to the risk of lung cancer |
| Q53287319 | Genetic polymorphisms in APE1 are associated with renal cell carcinoma risk in a Chinese population. |
| Q57319830 | Genetic variation in the DNA repair genes is predictive of outcome in lung cancer |
| Q27681153 | Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing |
| Q35103970 | Germ line variants of human N-methylpurine DNA glycosylase show impaired DNA repair activity and facilitate 1,N6-ethenoadenine-induced mutations |
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| Q37215375 | Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity |
| Q36028399 | Human population studies with cytogenetic biomarkers: review of the literature and future prospectives |
| Q51939346 | Identification and in silico analyses of novel TGFBR1 and TGFBR2 mutations in Marfan syndrome-related disorders. |
| Q30380482 | Identification of deleterious nsSNPs in α, μ, π and θ class of GST family and their influence on protein structure |
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