Transporter expression in non-cancerous and cancerous liver tissue from donors with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics.

scientific article published on 14 November 2017

Transporter expression in non-cancerous and cancerous liver tissue from donors with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/DMD.117.077289
P932PMC publication ID5776333
P698PubMed publication ID29138286

P50authorYurong LaiQ51696405
P2093author name stringAdrian S Ray
Laurent Salphati
Jashvant D Unadkat
Edward J Kelly
Cornelis E C A Hop
Raymond Evers
W Griffith Humphreys
Anita Mathias
Guangqing Xiao
Mingxiang Liao
Xiaoyan Chu
Bhagwat Prasad
Sarah Billington
Caroline A Lee
Christopher Rowbottom
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Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): quantification by liquid chromatography/tandem mass spectrometryQ35913104
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Breast cancer resistance protein and P-glycoprotein limit sorafenib brain accumulationQ39747662
Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1betaQ40054391
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Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomicsQ41585282
Role of extracellular matrix in regulating fenestrations of sinusoidal endothelial cells isolated from normal rat liverQ42611215
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Decreased expression of cytochromes P450 1A2, 2E1, and 3A4 and drug transporters Na+-taurocholate-cotransporting polypeptide, organic cation transporter 1, and organic anion-transporting peptide-C correlates with the progression of liver fibrosis inQ46565181
Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinomaQ47912725
Effect of nuclear receptor downregulation on hepatic expression of cytochrome P450 and transporters in chronic hepatitis C in association with fibrosis developmentQ50062283
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P4510describes a project that usesliquid chromatography–mass spectrometryQ873864
liquid chromatography-tandem mass spectrometryQ117788892
P433issue2
P304page(s)189-196
P577publication date2017-11-14
P1433published inDrug Metabolism and DispositionQ1261140
P1476titleTransporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics
P478volume46

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cites work (P2860)
Q88657543Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium
Q91179158Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood-Brain Barrier Measured by Quantitative Targeted Proteomics
Q91165087Protein abundance of hepatic drug transporters in patients with different forms of liver damage
Q92895937STAT3 signaling pathway plays importantly genetic and functional roles in HCV infection
Q92217096Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1

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