Patient-reported outcomes in relapsed ovarian cancer: results from a randomized Phase III study of trabectedin with pegylated liposomal doxorubicin (PLD) versus PLD alone

scientific article published on 2 July 2012

Patient-reported outcomes in relapsed ovarian cancer: results from a randomized Phase III study of trabectedin with pegylated liposomal doxorubicin (PLD) versus PLD alone is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YGYNO.2012.06.034
P8608Fatcat IDrelease_sntkmwx3nng53oxbddn6szghuq
P698PubMed publication ID22765965

P50authorBradley J. MonkQ107013145
P2093author name stringJan B Vermorken
Thomas J Herzog
Carolyn N Krasner
Antonio Nieto
Stanley B Kaye
Andres Poveda
Pilar Lardelli Claret
Trilok Parekh
Youn Choi Park
P2860cites workUse of Patient-Reported Outcomes in Randomized, Double-Blind, Placebo-Controlled Clinical TrialsQ24289168
The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncologyQ29615701
Quality-of-life comparisons in a randomized trial of interval secondary cytoreduction in advanced ovarian carcinoma: a Gynecologic Oncology Group study.Q30358112
Assessment of factors that contribute to decreased quality of life in Gynecologic Oncology Group ovarian cancer trialsQ30434513
Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials. Advanced Ovarian Cancer Trialists' GroupQ31962966
Randomized intergroup trial of cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year resultsQ33332312
Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group studyQ33348987
Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6-12 months) subpopulation of OVA-301 phase III randomized trialQ34413664
Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer delays third-line chemotherapy and prolongs the platinum-free intervalQ34413670
Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancerQ34546077
Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma.Q34552660
Quality-of-life issues in the management of epithelial ovarian cancerQ37049160
Determination of quality of life-related utilities for health states relevant to ovarian cancer diagnosis and treatmentQ37269617
Quality of life in patients with ovarian cancer: current state of researchQ39465503
Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancerQ40673230
Palliative therapy in advanced ovarian cancer: balancing patient expectations, quality of life and costQ40828663
Trabectedin plus pegylated liposomal Doxorubicin in recurrent ovarian cancer.Q43048172
Long-term survival in advanced ovarian cancer after cytoreduction and chemotherapy treatment.Q43953023
An international field study of the reliability and validity of a disease-specific questionnaire module (the QLQ-OV28) in assessing the quality of life of patients with ovarian cancerQ47805126
Longitudinal assessment of quality of life and lifestyle in newly diagnosed ovarian cancer patients: the roles of surgery and chemotherapy.Q53252193
Intraperitoneal cisplatin and paclitaxel in ovarian cancer.Q53263238
A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer.Q53298171
Development of a European Organization for Research and Treatment of Cancer questionnaire module to assess the quality of life of ovarian cancer patients in clinical trials: a progress report.Q53500222
Test-retest reliability of health state valuations collected with the EuroQol questionnaire.Q53655098
Psychometric properties and responsiveness of the EORTC quality of Life Questionnaire (QLQ-C30) in patients with breast, ovarian and lung cancer.Q53657259
Long-term follow-up confirms a survival advantage of the paclitaxel-cisplatin regimen over the cyclophosphamide-cisplatin combination in advanced ovarian cancerQ59647328
A comparison of ovarian cancer treatments: analysis of utility assessments of ovarian cancer patients, at-risk population, general population, and physiciansQ79830971
Ovarian cancerQ84605146
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectdoxorubicinQ18936
ovarian cancerQ172341
patientQ181600
P304page(s)161-167
P577publication date2012-07-02
P1433published inGynecologic OncologyQ5625182
P1476titlePatient-reported outcomes in relapsed ovarian cancer: results from a randomized Phase III study of trabectedin with pegylated liposomal doxorubicin (PLD) versus PLD alone
P478volume127

Reverse relations

cites work (P2860)
Q34898364Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models
Q36728989Clinical trials with pegylated liposomal Doxorubicin in the treatment of ovarian cancer
Q33921802Clinical utility of trabectedin for the treatment of ovarian cancer: current evidence.
Q38255906Ecteinascidins. A review of the chemistry, biology and clinical utility of potent tetrahydroisoquinoline antitumor antibiotics
Q36332234Estimating health-state utility values for patients with recurrent ovarian cancer using Functional Assessment of Cancer Therapy - General mapping algorithms
Q57058665Evaluating Progression-Free Survival as a Surrogate Outcome for Health-Related Quality of Life in Oncology: A Systematic Review and Quantitative Analysis
Q38728270Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line.
Q36382337Limitations to the use of carboplatin-based therapy in advanced ovarian cancer
Q26746924Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem"
Q92495346Marine-Derived Anticancer Agents: Clinical Benefits, Innovative Mechanisms, and New Targets
Q33705743Measuring symptoms as a critical component of drug development and evaluation in hematological diseases
Q38160258Optimizing treatment of the partially platinum-sensitive ovarian cancer patient
Q24201282Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer
Q34187661Pegylated liposomal doxorubicin in the management of ovarian cancer
Q47096976Systemic therapy for recurrent epithelial ovarian cancer: a clinical practice guideline
Q64239576TOP2A as marker of response to pegylated lyposomal doxorubicin (PLD) in epithelial ovarian cancers
Q34721579Trabectedin as a single agent and in combination with pegylated liposomal doxorubicin - activity against ovarian cancer cells.
Q47903356Update on relapsed ovarian cancer treatment: from new consensus to daily clinical practice
Q36929772Updates on drug discovery in ovarian cancer
Q47903322When nonplatinum is the answer: the role of trabectedin plus pegylated liposomal doxorubicin in recurrent ovarian cancer

Search more.