Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets

scientific article

Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/JNC.14249
P698PubMed publication ID29105065

P50authorChristopher J.H. PorterQ62833120
Philip MarriottQ37830307
Martin J. ScanlonQ43296605
Yijun PanQ57002116
Joseph A NicolazzoQ58243272
Kwok H C ChoyQ58243282
P2093author name stringJennifer L Short
Siew Y Chai
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Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acidQ28115048
Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's diseaseQ33201118
Hepatic steatosis in n-3 fatty acid depleted mice: focus on metabolic alterations related to tissue fatty acid compositionQ33388523
Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in the brainQ33556230
Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteinsQ34035426
High dietary consumption of trans fatty acids decreases brain docosahexaenoic acid but does not alter amyloid-beta and tau pathologies in the 3xTg-AD model of Alzheimer's disease.Q34919010
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The blood-brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid to the brain, and insulin facilitates transportQ38723657
Association of Serum Docosahexaenoic Acid With Cerebral AmyloidosisQ39482501
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Fatty Acid Binding Protein 5 Modulates Docosahexaenoic Acid-Induced Recovery in Rats Undergoing Spinal Cord Injury.Q41964462
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Diffusion of docosahexaenoic and eicosapentaenoic acids through the blood-brain barrier: An in situ cerebral perfusion study.Q46011960
Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's diseaseQ46651514
Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's diseaseQ46702194
Low-temperature improved-throughput method for analysis of brain fatty acids and assessment of their post-mortem stabilityQ46803631
Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic miceQ47316442
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function.Q47945490
Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissionsQ48153919
The blood-brain barrier and protein-mediated fatty acid uptake: role of the blood-brain barrier as a metabolic barrier: An Editorial Comment for 'The blood-brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid toQ48233444
Extension of a new two-trial memory task in the rat: influence of environmental context on recognition processes.Q52043776
Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid.Q52148129
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
blood–brain barrierQ221694
P304page(s)81-92
P577publication date2017-11-03
P1433published inJournal of NeurochemistryQ6295643
P1476titleReduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets
P478volume144

Reverse relations

Q90567799Dietary Intake of Green Nut Oil or DHA Ameliorates DHA Distribution in the Brain of a Mouse Model of Dementia Accompanied by Memory Recoverycites workP2860