A phase I clinical trial of binimetinib in combination with FOLFOX in patients with advanced metastatic colorectal cancer who failed prior standard therapy.

scientific article published on 18 July 2017

A phase I clinical trial of binimetinib in combination with FOLFOX in patients with advanced metastatic colorectal cancer who failed prior standard therapy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.19336
P932PMC publication ID5668088
P698PubMed publication ID29108355

P50authorTimothy SynoldQ78536675
P2093author name stringPaul Frankel
Yuan Chen
Marwan Fakih
Jun Gong
Daneng Li
Dean Lim
Gagandeep Singh
Vincent Chung
Kurt Melstrom
May Cho
Stephen Sentovich
Joseph Chao
Eloise Luevanos
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Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI-H) metastatic endometrial cancerQ41099951
MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashionQ42512056
OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-Go fashion in advanced colorectal cancer--a GERCOR studyQ46900220
Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.Q53410679
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
phase I clinical trialQ5452194
metastatic colon cancerQ108566365
P304page(s)79750-79760
P577publication date2017-07-18
P1433published inOncotargetQ1573155
P1476titleA phase I clinical trial of binimetinib in combination with FOLFOX in patients with advanced metastatic colorectal cancer who failed prior standard therapy
P478volume8

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Q53705974BRAF and MEK Inhibitors: Use and Resistance in BRAF-Mutated Cancers.cites workP2860

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