Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines

scientific article published in April 1989

Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1200/JCO.1989.7.4.486
P698PubMed publication ID2647914

P50authorJanice P DutcherQ90323603
P2093author name stringJ H Doroshow
K A Margolin
R I Fisher
G R Weiss
M J Hawkins
M B Atkins
H S Jaffe
A A Rayner
M Roper
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)486-498
P577publication date1989-04-01
P1433published inJournal of Clinical OncologyQ400292
P1476titleInterleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines
P478volume7

Reverse relations

cites work (P2860)
Q49332278A Case of Myocarditis and Near-Lethal Arrhythmia Associated With Interleukin-2 Therapy
Q47563772A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects
Q71643806A phase I trial of continuous infusion interleukin-4 (IL-4) alone and following interleukin-2 (IL-2) in cancer patients
Q57749178Adoptive immunotherapy of advanced melanoma patients with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes selected in vitro with low doses of IL-2
Q79150748Antineoplastic Effects of Partially HLA-Matched Irradiated Blood Mononuclear Cells in Patients With Renal Cell Carcinoma
Q35753505Application of IL-2 and other cytokines in renal cancer
Q38815946Arrhythmias and Other Electrophysiology Issues in Cancer Patients Receiving Chemotherapy or Radiation
Q34107958Biochemotherapy for melanoma
Q44541472Bolus Followed by Continuous Infusion Interleukin-2 in Patients with Metastatic Malignant Melanoma and Kidney Cancer Previously Treated with Interleukin-2
Q38313870Cancer chemotherapy and cardiac arrhythmias: a review.
Q33559591Cardiomyopathy associated with high-dose interleukin-2 therapy
Q41689551Cardiovascular toxicity with cancer chemotherapy
Q41525667Case Report. Colosplenic Fistula in a Patient Treated with Interleukin-2 for Malignant Melanoma
Q36589103Central Nervous System Toxicity of Biological Response Modifiers
Q35580479Chemokines, costimulatory molecules and fusion proteins for the immunotherapy of solid tumors
Q46903999Chronic interleukin-2 treatment in awake sheep causes minimal or no injury to the lung microvascular barrier
Q40953955Cisplatin-based polychemotherapy reduces the natural cytotoxicity of peripheral blood mononuclear cells in patients with advanced ovarian carcinoma and their in vitro responsiveness to interleukin-12 incubation
Q81399311Clinical outcome of combined immunotherapy with low-dose interleukin-2 and interferon-alpha for Japanese patients with metastatic renal cell carcinoma who had undergone radical nephrectomy: a preliminary report
Q33355316Clinical toxicity of interleukin-2.
Q72284657Colon adenocarcinoma cells inhibit anti-CD3-activated killer cell induction
Q61911235Combination of interleukin-2 and gamma interferon in metastatic renal cell carcinoma
Q40875316Common cancers--immunotherapy and multidisciplinary therapy: Parts III and IV.
Q38267711Concise review: engineering the fusion of cytokines for the modulation of immune cellular responses in cancer and autoimmune disorders
Q36723646Cytokines in anticancer therapy
Q70599547Dissociation of natural killer and lymphocyte-activated killer cell lytic activities in human CD3- large granular lymphocytes
Q84627320Drug-induced atrial fibrillation
Q33415481Durable responses and reversible toxicity of high-dose interleukin-2 treatment of melanoma and renal cancer in a Community Hospital Biotherapy Program
Q68326713Ecogramostim and pre-existing autoimmune thyroid disease
Q52592617Electrophysiologic Toxicity of Chemoradiation.
Q39714477Feasibility of high-dose interleukin-2 in heavily pretreated pediatric cancer patients
Q40754856Haemodynamic effects of recombinant interleukin-2 administered by constant infusion
Q59400683High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014
Q71015279High-dose continuous intravenous infusion of interleukin-2 therapy for metastatic renal cell carcinoma: the University of Chicago experience
Q80508965Homing of radiolabelled recombinant interleukin-2 activated natural killer cells and their efficacy in adoptive immunotherapy against murine fibrosarcoma
Q37253572Human autologous tumor-specific T cells in malignant melanoma
Q35661491IL-2 regulates the expression of the tumor suppressor IL-24 in melanoma cells.
Q90623091Immunotherapy Against Gliomas: is the Breakthrough Near?
Q35157638Immunotherapy for renal cell carcinoma
Q40539148Immunotherapy for renal cell carcinoma: the era of interleukin-2-based treatment
Q71931101Immunotherapy of malignant melanoma
Q37463892Immunotherapy of metastatic renal cell carcinoma
Q47287952Improved survival and tumor control with Interleukin-2 is associated with the development of immune-related adverse events: data from the PROCLAIMSM registry
Q39232767Interleukin-2 in cancer treatment: disappointing or (still) promising? A review
Q34306890Interleukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer
Q38996288Irradiated mononuclear cells express significant in vitro cytotoxic activity: promise for in vivo clinical efficacy of irradiated mismatched donor lymphocytes infusion.
Q34579252Kidney cancer: the Cytokine Working Group experience (1986-2001): part II. Management of IL-2 toxicity and studies with other cytokines
Q36663524Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy
Q44312624Long-Term Survival in Patients with Metastatic Renal Cell Carcinoma Treated with Continuous Intravenous Infusion of Recombinant Interleukin-2: The Experience of a Single Institution
Q33694402Making the transition from hospital to home: caring for the newly diagnosed child with cancer
Q40948910Medical treatment of advanced renal cell carcinoma: present options and future directions
Q53393882Microscopic Venous Infiltration As Predictor Of Relapse In Renal Cell Carcinoma
Q38180319Mitigating the toxic effects of anticancer immunotherapy
Q36134535NG-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthesis, ameliorates interleukin 2-induced capillary leakage and reduces tumour growth in adenocarcinoma-bearing mice
Q41051859Nursing management of patients receiving biological therapy
Q40755408Phase I trial of intravenous infusion of ex-vivo-activated autologous blood-derived macrophages in patients with non-small-cell lung cancer: toxicity and immunomodulatory effects
Q40707862Phase II study of low dose cyclophosphamide and intravenous interleukin-2 in metastatic renal cancer
Q36138945Plasma nitrate plus nitrite changes during continuous intravenous infusion interleukin 2.
Q37686896Prolonged interleukin-2 (IL-2) treatment can augment immune activation without enhancing antitumor activity in renal cell carcinoma
Q45770715Prophylactic intervention in radiation-leukemia-virus-induced murine lymphoma by the biological response modifier polysaccharide K.
Q40482190Pure Red Cell Aplasia Following Interleukin-2 Therapy.
Q37803895Rationale for immunotherapy of renal cell carcinoma
Q71900148Recombinant interleukin-2 acts like a class I antiarrhythmic drug on human cardiac sodium channels
Q45106794Recombinant interleukin-2 in metastatic renal cell carcinoma—A European multicentre phase II study
Q70501182Renal, metabolic, and hemodynamic side-effects of interleukin-2 and/or interferon alpha: evidence of a risk/benefit advantage of subcutaneous therapy
Q36231087Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF
Q35823805Selective modulation of human natural killer cells in vivo after prolonged infusion of low dose recombinant interleukin 2
Q28067610Spotlight on pembrolizumab in non-small cell lung cancer: the evidence to date
Q35979169Subcutaneous low-dose recombinant interleukin 2 and alpha-interferon in patients with metastatic renal cell carcinoma.
Q40684209Successful treatment of retinoic acid syndrome with high‐dose dexamethasone pulse therapy in a child with acute promyelocytic leukemia treated with ATRA
Q39264898Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities
Q34569970The biological treatment of renal-cell carcinoma and melanoma
Q35044419The high-dose aldesleukin "select" trial: a trial to prospectively validate predictive models of response to treatment in patients with metastatic renal cell carcinoma
Q37427683The immunotherapy of human cancer with interleukin 2: present status and future directions
Q37047969Three phase II cytokine working group trials of gp100 (210M) peptide plus high-dose interleukin-2 in patients with HLA-A2-positive advanced melanoma
Q36718958Update on the application of interleukin-2 in the treatment of renal cell carcinoma
Q41664945Vascular leak syndrome: a side effect of immunotherapy

Search more.