Up-regulation of caveolin-1 by DJ-1 attenuates rat pulmonary arterial hypertension by inhibiting TGFβ/Smad signaling pathway

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Up-regulation of caveolin-1 by DJ-1 attenuates rat pulmonary arterial hypertension by inhibiting TGFβ/Smad signaling pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2017.10.019
P698PubMed publication ID29069575

P2093author name stringXiaoping Zhang
Ying Liu
Weiwei Gao
Xian'en Fa
Runxia Shao
Daijian Liu
P2860cites workMutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonismQ24321359
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Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout miceQ28508575
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DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.Q33734076
Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammationQ33795736
Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotypeQ35437211
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasiaQ35789293
Chronic hypoxia induces right heart failure in caveolin-1-/- mice.Q36042487
Requirement of miR-9-dependent regulation of Myocd in PASMCs phenotypic modulation and proliferation induced by hepatopulmonary syndrome rat serumQ36125400
Hypoxia-induced migration in pulmonary arterial smooth muscle cells requires calcium-dependent upregulation of aquaporin 1Q36178060
Regulation and characteristics of vascular smooth muscle cell phenotypic diversity.Q36870887
Neuroprotective function of DJ-1 in Parkinson's diseaseQ36899553
DJ-1 deficiency impairs glutamate uptake into astrocytes via the regulation of flotillin-1 and caveolin-1 expression.Q37040352
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responsesQ37061628
Inhibitory effect of NBL1 on PDGF-BB-induced human PASMC proliferation through blockade of PDGFβ-p38MAPK pathwayQ37220791
Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activationQ37358578
Suppression of the expression of hypoxia-inducible factor-1α by RNA interference alleviates hypoxia-induced pulmonary hypertension in adult ratsQ37426657
Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progressionQ37690429
Cavin proteins: New players in the caveolae fieldQ37723786
Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertensionQ37727384
The transforming growth factor-β-bone morphogenetic protein type signalling pathway in pulmonary vascular homeostasis and diseaseQ38104321
Asymmetric dimethyl arginine induces pulmonary vascular dysfunction via activation of signal transducer and activator of transcription 3 and stabilization of hypoxia-inducible factor 1-alphaQ38993830
DJ-1 mediates paraquat-induced dopaminergic neuronal cell death.Q39596576
MicroRNA-30c contributes to the development of hypoxia pulmonary hypertension by inhibiting platelet-derived growth factor receptor β expressionQ41060820
Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesisQ42463360
A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary HypertensionQ42752955
Caveolin-1 deficiency stimulates neointima formation during vascular injuryQ44955714
Melatonin attenuates hypoxic pulmonary hypertension by inhibiting the inflammation and the proliferation of pulmonary arterial smooth muscle cellsQ46435567
Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension.Q46503340
Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cellsQ46755210
A novel ACE2 activator reduces monocrotaline-induced pulmonary hypertension by suppressing the JAK/STAT and TGF-β cascades with restored caveolin-1 expression.Q52654089
DJ-1/park7 protects against neointimal formation via the inhibition of vascular smooth muscle cell growth.Q53350230
Cellular responses to hypoxia in the pulmonary circulationQ57097540
Upregulation of Na+/Ca2+ exchanger contributes to the enhanced Ca2+ entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertensionQ57374647
Short-Term Administration of a Cell-Permeable Caveolin-1 Peptide Prevents the Development of Monocrotaline-Induced Pulmonary Hypertension and Right Ventricular HypertrophyQ57374840
Chronic administration of adrenomedullin attenuates hypoxic pulmonary vascular structural remodeling and inhibits proadrenomedullin N-terminal 20-peptide production in ratsQ79699023
Proteomic analysis of lung tissues from patients with pulmonary arterial hypertensionQ82265270
PDGF receptor blocker for pulmonary hypertension: a new agent in therapeutic arsenalQ83176520
Transgelin as a therapeutic target to prevent hypoxic pulmonary hypertensionQ87167197
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)192-198
P577publication date2017-10-22
P1433published inExperimental Cell ResearchQ1524289
P1476titleUp-regulation of caveolin-1 by DJ-1 attenuates rat pulmonary arterial hypertension by inhibiting TGFβ/Smad signaling pathway
P478volume361

Reverse relations

cites work (P2860)
Q89790049Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53
Q88574928Elevated expression of DJ-1 (encoded by the human PARK7 gene) protects neuronal cells from sevoflurane-induced neurotoxicity
Q88590354Hypoxia-induced autophagy activation through NF-κB pathway regulates cell proliferation and migration to induce pulmonary vascular remodeling
Q98188932Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes

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