Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats

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Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJP.1097
P698PubMed publication ID28877402

P50authorEsther BerrocosoQ55153713
P2093author name stringM Chalus
J A Mico
A Eschalier
E Chapuy
A Sors
D Ardid
T Chaumette
L Bravo
F Marchand
M Llorca-Torralba
P2860cites workSomatodendritic alpha2-adrenoceptors in the locus coeruleus are involved in the in vivo modulation of cortical noradrenaline release by the antidepressant desipramineQ47777731
Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivityQ47976388
Spinal and pontine alpha2-adrenoceptors have opposite effects on pain-related behavior in the neuropathic rat.Q48401603
Depressive-like states heighten the aversion to painful stimuli in a rat model of comorbid chronic pain and depressionQ48423673
Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic ratsQ48461794
In vivo effect of tramadol on locus coeruleus neurons is mediated by alpha2-adrenoceptors and modulated by serotoninQ48520579
The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic painQ48805462
Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats.Q51995351
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Noxious thermal input from the rat tail: Modulation by descending inhibitory influencesQ67311754
Involvement of histamine in naloxone-resistant and naloxone-sensitive models of swim stress-induced antinociception in the mouseQ68017605
Streptozocin-induced diabetic rats: behavioural evidence for a model of chronic painQ72792853
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Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptorQ34249836
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A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.Q34554719
Novel histamine H3 receptor antagonists GSK189254 and GSK334429 are efficacious in surgically-induced and virally-induced rat models of neuropathic painQ34731433
Noradrenergic pain modulationQ36618448
Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standardsQ37278667
Mechanistic characterization of S 38093, a novel inverse agonist at histamine H3 receptorsQ38881227
In vivo pharmacological profile of S 38093, a novel histamine H3 receptor inverse agonistQ38896625
Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxaneQ39107047
Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain.Q40075154
Role of histamine in rodent antinociceptionQ42115852
Inhibition of cortical acetylcholine release and cognitive performance by histamine H3 receptor activation in ratsQ42581834
Cholinergic Neurotransmission in the Posterior Insular Cortex Is Altered in Preclinical Models of Neuropathic Pain: Key Role of Muscarinic M2 Receptors in Donepezil-Induced AntinociceptionQ43128774
Rodent antinociception following acute treatment with different histamine receptor agonists and antagonistsQ44099995
Activation of spinal histamine H3 receptors inhibits mechanical nociceptionQ44473256
Inhibition of chemical and low-intensity mechanical nociception by activation of histamine H3 receptorsQ46385200
Comparative antiallodynic activity of morphine, pregabalin and lidocaine in a rat model of neuropathic pain produced by one oxaliplatin injectionQ46503934
P433issue1
P921main subjectneuropathic painQ2798704
P304page(s)127-141
P577publication date2017-09-06
P1433published inEuropean Journal of PainQ4548992
P1476titleEffects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats
P478volume22

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Q92669907Monoamines as Drug Targets in Chronic Pain: Focusing on Neuropathic Paincites workP2860

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