Synthesized Heparan Sulfate Competitors Attenuate Pseudomonas aeruginosa Lung Infection.

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Synthesized Heparan Sulfate Competitors Attenuate Pseudomonas aeruginosa Lung Infection. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS19010207
P932PMC publication ID5796156
P698PubMed publication ID29315274

P50authorCristina CiganaQ56223988
Nicola Ivan LorèQ57630158
Annamaria NaggiQ59387864
P2093author name stringAlessandra Bragonzi
Camilla Riva
Ida De Fino
Barbara Sipione
Lorenza Spagnuolo
Noemi Veraldi
Medede Melessike
Elisa Calzi
P2860cites workThe heparan sulfate binding sequence of interferon-gamma increased the on rate of the interferon-gamma-interferon-gamma receptor complex formationQ28268586
Pseudomonas aeruginosa exploits lipid A and muropeptides modification as a strategy to lower innate immunity during cystic fibrosis lung infectionQ28472320
Molecular weight determination of heparin and dermatan sulfate by size exclusion chromatography with a triple detector arrayQ31139647
BIIL 284 reduces neutrophil numbers but increases P. aeruginosa bacteremia and inflammation in mouse lungsQ34180324
Nonmucoid Pseudomonas aeruginosa expresses alginate in the lungs of patients with cystic fibrosis and in a mouse model.Q34232085
Cystic fibrosis-niche adaptation of Pseudomonas aeruginosa reduces virulence in multiple infection hostsQ34256578
Examination of the substrate specificity of heparin and heparan sulfate lyasesQ34324156
IL-17A impairs host tolerance during airway chronic infection by Pseudomonas aeruginosaQ34527023
Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokinesQ34762409
Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis airways influences virulence of Staphylococcus aureus in vitro and murine models of co-infectionQ35113179
Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replicationQ35288221
Heparin derivatives for the targeting of multiple activities in the inflammatory response.Q51025748
The catalytic machinery of chondroitinase ABC I utilizes a calcium coordination strategy to optimally process dermatan sulfate.Q51134862
Assessing Pseudomonas aeruginosa virulence and the host response using murine models of acute and chronic lung infection.Q51724332
The involvement of glycosaminoglycans in airway disease associated with cystic fibrosis.Q53252194
Pseudomonas aeruginosaMicroevolution during Cystic Fibrosis Lung Infection Establishes Clones with Adapted VirulenceQ61477540
Host genetic diversity influences the severity of Pseudomonas aeruginosa pneumonia in the Collaborative Cross miceQ35756714
Host-pathogen interplay in the respiratory environment of cystic fibrosisQ35799736
Pseudomonas aeruginosa pili and flagella mediate distinct binding and signaling events at the apical and basolateral surface of airway epitheliumQ35873580
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapyQ35990705
Cystic fibrosis: a mucosal immunodeficiency syndrome.Q36623329
The 'sweet' and 'bitter' involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevanceQ37346515
Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo.Q37623543
Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancerQ37736668
Chronic obstructive pulmonary disease (COPD): evaluation from clinical, immunological and bacterial pathogenesis perspectivesQ38192501
The Pseudomonas aeruginosa PAO1 Two-Component Regulator CarSR Regulates Calcium Homeostasis and Calcium-Induced Virulence Factor Production through Its Regulatory Targets CarO and CarP.Q38294389
New insights into the inhibition of human neutrophil elastase by heparinQ38311212
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Defining the interleukin-8-binding domain of heparan sulfateQ38336349
Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections.Q38522938
The Role of Neutrophil Elastase Inhibitors in Lung DiseasesQ38690959
The clinical impact of major comorbidities on idiopathic pulmonary fibrosisQ38748617
Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models.Q39184529
The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infectionQ40450037
The IL-17A/IL-17RA axis in pulmonary defence and immunopathologyQ40733585
Role of heparan sulphate proteoglycans as potential receptors for non-piliated Pseudomonas aeruginosa adherence to non-polarised airway epithelial cells.Q40824581
Acute Exacerbations of COPD Are Associated With Increased Expression of Heparan Sulfate and Chondroitin Sulfate in BAL.Q41081198
Dampening Host Sensing and Avoiding Recognition in Pseudomonas aeruginosa Pneumonia.Q42043676
Heparin and heparan sulphate are inhibitors of human leucocyte elastaseQ43768379
Sputum sol neutrophil elastase activity in bronchiectasis: differential modulation by syndecan-1.Q44408401
Undersulfated and glycol-split heparins endowed with antiangiogenic activityQ44754685
Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splittingQ45221614
Endothelial activation and increased heparan sulfate expression in cystic fibrosisQ47774987
Increased deposition of glycosaminoglycans and altered structure of heparan sulfate in idiopathic pulmonary fibrosisQ48019677
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
P577publication date2018-01-09
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleSynthesized Heparan Sulfate Competitors Attenuate Pseudomonas aeruginosa Lung Infection
P478volume19

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cites work (P2860)
Q98177430Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease
Q57296631Lung Diseases: Chronic Respiratory Infections
Q91798207Non-Anticoagulant Heparins as Heparanase Inhibitors

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