| P2093 | author name string | Jing Wang | |
| | Degeng Wang | |
| | Xiaolin Zhou | |
| | Haowei Yi | |
| | Geoffrey Talmon | |
| | Liying Geng | |
| P2860 | cites work | LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines | Q21560941 |
| | R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 | Q24292884 |
| | R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling | Q24307371 |
| | Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling | Q24310750 |
| | TGF beta signals through a heteromeric protein kinase receptor complex | Q24337608 |
| | Lgr5 marks cycling, yet long-lived, hair follicle stem cells. | Q53447869 |
| | Mutant PIK3CA-bearing colon cancer cells display increased metastasis in an orthotopic model. | Q53568151 |
| | Smad3 deficiency promotes tumorigenesis in the distal colon of ApcMin/+ mice. | Q53589404 |
| | Differential Notch and TGFbeta signaling in primary colorectal tumors and their corresponding metastases. | Q54967629 |
| | DAP kinase links the control of apoptosis to metastasis | Q59083516 |
| | Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin | Q63406949 |
| | Comparison of growth requirements of two human intratumoral colon carcinoma cell lines in monolayer and soft agarose | Q68132129 |
| | A scaling normalization method for differential expression analysis of RNA-seq data | Q24628783 |
| | Wnt signaling, lgr5, and stem cells in the intestine and skin | Q24646716 |
| | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data | Q27860819 |
| | Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily | Q28115269 |
| | Identification of stem cells in small intestine and colon by marker gene Lgr5 | Q28131701 |
| | Mechanism of activation of the TGF-beta receptor | Q28245861 |
| | Smad transcription factors | Q28284775 |
| | Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region | Q28291156 |
| | Crypt stem cells as the cells-of-origin of intestinal cancer | Q28304418 |
| | Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes | Q28508338 |
| | Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro | Q29616198 |
| | Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells | Q30529353 |
| | TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study | Q33293871 |
| | MicroRNA-192 suppresses liver metastasis of colon cancer | Q33594662 |
| | IAP regulation of metastasis | Q33638504 |
| | Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β | Q33694667 |
| | Modeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data directed for maximization of analytical reliability | Q33721845 |
| | Identification of a novel TGFβ/PKA signaling transduceome in mediating control of cell survival and metastasis in colon cancer | Q33894754 |
| | Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin | Q34572166 |
| | R-Spondin family members regulate the Wnt pathway by a common mechanism | Q36678039 |
| | Recurrent R-spondin fusions in colon cancer | Q36949683 |
| | Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury | Q36997442 |
| | Detection algorithm for the validation of human cell lines | Q37169146 |
| | Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection | Q37462991 |
| | Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF. | Q38797398 |
| | RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer. | Q39029239 |
| | Phosphatase PRL-3 Is a Direct Regulatory Target of TGFβ in Colon Cancer Metastasis | Q39630626 |
| | Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma | Q40989877 |
| | Initiation and characterization of cultures of human colonic carcinoma with different biological characteristics utilizing feeder layers of confluent fibroblasts | Q42802019 |
| | Frequent loss of SMAD4/DPC4 protein in colorectal cancers | Q43006283 |
| | Lineage tracing in the intestinal epithelium | Q43073816 |
| | Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration | Q43548445 |
| | LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine | Q43579801 |
| | Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients | Q44403626 |
| | Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers. | Q45345221 |
| | Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model | Q46469103 |
| | Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells | Q47735652 |
| | The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis. | Q53243282 |
| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | colon cancer | Q18555025 |
| | cancer metastasis | Q120912394 |
| P304 | page(s) | 6589-6602 | |
| P577 | publication date | 2017-09-22 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | R-Spondin1/LGR5 Activates TGFβ Signaling and Suppresses Colon Cancer Metastasis | |
| P478 | volume | 77 | |