Involvement of spinal PKA/CREB signaling pathway in the development of bone cancer pain

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Involvement of spinal PKA/CREB signaling pathway in the development of bone cancer pain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1734-1140(13)71049-1
P698PubMed publication ID23950594

P2093author name stringHong Wang
Zheng Chen
Dong-Hua Shao
Li-Hua Hang
Jian-Ping Yang
P2860cites workPeripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn.Q46019149
Inhibition of the cyclic adenosine monophosphate pathway attenuates neuropathic pain and reduces phosphorylation of cyclic adenosine monophosphate response element-binding in the spinal cord after partial sciatic nerve ligation in rats.Q46879151
Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinaseQ48175112
Involvement of kainate receptors in the analgesic but not hypnotic effects induced by inhalation anestheticsQ48222061
cAMP response element-binding protein is a primary hub of activity-driven neuronal gene expressionQ48776802
Efficient analysis of experimental observations.Q52767736
Assessment of cancer pain: a prospective evaluation in 2266 cancer patients referred to a pain serviceQ71676094
Transdermal buprenorphine in the treatment of cancer and non-cancer pain - the results of multicenter studies in PolandQ82041536
Activation of spinal TDAG8 and its downstream PKA signaling pathway contribute to bone cancer pain in ratsQ83929418
Analgesia and serum assays of controlled-release dihydrocodeine and metabolites in cancer patients with painQ84118306
Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection.Q24815537
Downregulation of the cAMP/PKA pathway in PC12 cells overexpressing NCS-1Q28293208
Quantitative assessment of tactile allodynia in the rat pawQ29617366
Function and regulation of CREB family transcription factors in the nervous systemQ29619559
Down-regulation of Toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat modelQ33645150
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neuronsQ33907117
Mechanism of cancer painQ33953901
Involvement of 5-hydroxytryptamine type 3 receptors in sevoflurane-induced hypnotic and analgesic effects in miceQ34141059
The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral painQ35847195
Sex, gender, and pain: a review of recent clinical and experimental findingsQ37180957
Nociceptor sensitization in pain pathogenesisQ37254618
Opioid-induced bowel dysfunction in cancer-related pain: causes, consequences, and a novel approach for its managementQ37575225
The use of morphine to treat cancer-related pain: a synthesis of quantitative and qualitative researchQ37604007
Mechanisms of cancer-induced bone painQ37891305
Walker 256 tumor-bearing rats as a model to study cancer painQ40173487
A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cellsQ40275303
Effects of protein kinase a activation on the responses of primate spinothalamic tract neurons to mechanical stimuliQ44046164
Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neuronsQ44121155
Adenylate cyclase inhibition attenuates neuropathic pain but lacks pre-emptive effects in rats.Q45918173
Protein kinase A-dependence of the supraspinally mediated analgesic effects of gabapentin on thermal and mechanical hypersensitivity.Q45981932
P433issue3
P921main subjectbone cancerQ18554919
P304page(s)710-716
P577publication date2013-01-01
P1433published inPharmacological ReportsQ15766499
P1476titleInvolvement of spinal PKA/CREB signaling pathway in the development of bone cancer pain
P478volume65

Reverse relations

cites work (P2860)
Q64079471Antinociceptive effects of Ginsenoside Rb1 in a rat model of cancer-induced bone pain
Q37114764CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice
Q38807420Connexin 43 Mediates CXCL12 Production from Spinal Dorsal Horn to Maintain Bone Cancer Pain in Rats
Q43591397Downregulation of connexin36 in mouse spinal dorsal horn neurons leads to mechanical allodynia
Q55450411Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia.
Q54209749Evidence for involvement of spinal RANTES in the antinociceptive effects of triptolide, a diterpene triepoxide, in a rat model of bone cancer pain.
Q37549586Inhibition of the cAMP/PKA/CREB Pathway Contributes to the Analgesic Effects of Electroacupuncture in the Anterior Cingulate Cortex in a Rat Pain Memory Model
Q30886992Involvement of Spinal Bv8/Prokineticin 2 in a Rat Model of Cancer-Induced Bone Pain
Q64377501Positive feedback regulation between microRNA-132 and CREB in spinal cord contributes to bone cancer pain in mice
Q48833658RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain.
Q28075980The Walker 256 Breast Cancer Cell- Induced Bone Pain Model in Rats
Q47945057The role and mechanism of glutamic NMDA receptor in the mechanical hyperalgesia in diabetic rats.

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