Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children.

scientific article published on 16 October 2017

Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children. is …
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scholarly articleQ13442814

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P356DOI10.1128/AAC.01194-17
P8608Fatcat IDrelease_pqh4otew65dvbk2d5226rerhvm
P932PMC publication ID5740334
P698PubMed publication ID29038273

P50authorOliver A CornelyQ57062280
P2093author name stringGeorg Hempel
Andreas H Groll
Peter Bader
Thomas Lehrnbecher
Carsten Müller
Fedja Farowski
Silke Gastine
Judith Ullmann-Moskovits
P2860cites workA randomized, double-blind, double-dummy, multicenter trial of voriconazole and fluconazole in the treatment of esophageal candidiasis in immunocompromised patientsQ28189320
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Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trialQ28278518
PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.Q33219671
Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studiesQ33392206
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The initial 96 hours of invasive pulmonary aspergillosis: histopathology, comparative kinetics of galactomannan and (1->3) β-d-glucan and consequences of delayed antifungal therapyQ34290097
Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or allogeneic haemopoietic stem-cell transplantationQ34427584
Randomized, double-blind trial of fluconazole versus voriconazole for prevention of invasive fungal infection after allogeneic hematopoietic cell transplantationQ34450423
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Pharmacodynamics of Voriconazole in Children: Further Steps along the Path to True Individualized TherapyQ36730105
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Voriconazole Dosing in Children Younger Than 3 Years Undergoing Cancer Chemotherapy or Hematopoietic Stem Cell TransplantationQ38838267
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Utility of voriconazole therapeutic drug monitoring: a meta-analysisQ40679884
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Voriconazole drug monitoring in the management of invasive fungal infection in immunocompromised children: a prospective studyQ44106107
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The effect of therapeutic drug monitoring on safety and efficacy of voriconazole in invasive fungal infections: a randomized controlled trialQ44924916
Pharmacodynamics of voriconazole in a dynamic in vitro model of invasive pulmonary aspergillosis: implications for in vitro susceptibility breakpoints.Q47568169
Correlation of CYP2C19 phenotype with voriconazole plasma concentration in children.Q51067119
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A Physiologically Based Pharmacokinetic Model for Voriconazole Disposition Predicts Intestinal First-pass Metabolism in ChildrenQ57730442
Pulmonary aspergillosis: early diagnosis improves survivalQ70877231
Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEMQ77296898
Monitoring of voriconazole plasma concentrations in immunocompromised paediatric patientsQ84574274
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
voriconazoleQ412236
P577publication date2017-12-21
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titlePharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children
P478volume62