Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts

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Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts is …
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scholarly articleQ13442814

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P356DOI10.1002/JBMR.3295
P932PMC publication ID5771992
P698PubMed publication ID28914985

P2093author name stringYasuyoshi Ueki
Teruhito Yoshitaka
Tetsuya Yoshimoto
Tomoyuki Mukai
Kotoe Mayahara
Mizuho Kittaka
Jeffrey P Gorski
P2860cites workLoss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubismQ24299210
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Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice.Q51997176
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NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubismQ30157499
Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubismQ30168144
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Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix propertiesQ33787888
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Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.Q34942166
Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMPQ35191039
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Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor BlockadeQ36536688
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SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (M-CSF) stimulation and regulates M-CSF-induced signalingQ40489357
The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagenQ40513100
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P4510describes a project that usesImageJQ1659584
ImageQuantQ112270642
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)167-181
P577publication date2017-09-15
P1433published inJournal of Bone and Mineral ResearchQ15750941
P1476titleCherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts
P478volume33

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cites work (P2860)
Q91272403A rare disease patient/caregiver perspective on fair pricing and access to gene-based therapies
Q91740956Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice
Q64109984Tankyrase (PARP5) Inhibition Induces Bone Loss through Accumulation of Its Substrate SH3BP2