Clinical significance of YAP1 activation in head and neck squamous cell carcinoma.

scientific article published on 27 November 2017

Clinical significance of YAP1 activation in head and neck squamous cell carcinoma. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.22666
P932PMC publication ID5762311
P698PubMed publication ID29340043

P50authorEui Hyun KimQ88007302
P2093author name stringJu-Seog Lee
Kee Hwan Kwon
Young Chan Lee
Bo Hwa Sohn
Dongjin Lee
Sun Young Yim
Young-Gyu Eun
P2860cites workGlobal cancer statisticsQ22241238
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approachQ24633776
Cluster analysis and display of genome-wide expression patternsQ24644463
A comparison of normalization methods for high density oligonucleotide array data based on variance and biasQ27860710
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Comprehensive genomic characterization of head and neck squamous cell carcinomasQ28256121
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAPQ28266862
Mutational landscape and significance across 12 major cancer typesQ28300353
The mutational landscape of head and neck squamous cell carcinomaQ29614654
Multiclass cancer diagnosis using tumor gene expression signaturesQ29615780
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosisQ29619851
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and wartsQ29620457
Pembrolizumab for the treatment of non-small-cell lung cancerQ29620851
Atezolizumab as first-line treatment in cisplatin-ineligible patients with locally advanced and metastatic urothelial carcinoma: a single-arm, multicentre, phase 2 trial.Q30275266
The Hippo signaling pathway in stem cell biology and cancerQ30410176
Analysis of gene expression data using BRB-ArrayTools.Q33448521
Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancerQ33849646
KRAS and YAP1 converge to regulate EMT and tumor survivalQ33946244
Yes-associated protein expression in head and neck squamous cell carcinoma nodal metastasisQ34077954
Hippo Pathway Effector Yap Is an Ovarian Cancer OncogeneQ34267908
Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.Q34602664
Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladderQ34840601
Identification and validation of a multigene predictor of recurrence in primary laryngeal cancerQ34946875
Correlation of somatic mutation and expression identifies genes important in human glioblastoma progression and survivalQ35085742
Prognostic Value of Yes-Associated Protein 1 (YAP1) in Various Cancers: A Meta-AnalysisQ35742770
A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell CarcinomaQ35752244
Significant association of oncogene YAP1 with poor prognosis and cetuximab resistance in colorectal cancer patientsQ35885488
The emerging roles of YAP and TAZ in cancerQ36035567
A 13-gene signature prognostic of HPV-negative OSCC: discovery and external validationQ36672862
Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinomaQ36939981
The Hippo pathway and human cancer.Q38087215
Inactivation of Hippo Pathway Is Significantly Associated with Poor Prognosis in Hepatocellular CarcinomaQ38828541
PD-1 and PD-L1 inhibitors in melanoma treatment: past success, present application and future challenges.Q38838649
Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trialQ38849759
The Hippo pathway transcriptional co-activator, YAP, confers resistance to cisplatin in human oral squamous cell carcinomaQ38890549
The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal CancerQ38903548
YAP1 is a potential biomarker for cetuximab resistance in head and neck cancerQ38978179
Molecular and Biochemical Aspects of the PD-1 Checkpoint PathwayQ38996832
Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis.Q39586964
The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer.Q40814745
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathwayQ44591663
Application of comparative functional genomics to identify best-fit mouse models to study human cancerQ45163567
miRWalk2.0: a comprehensive atlas of microRNA-target interactionsQ46692723
Shar-pei mediates cell proliferation arrest during imaginal disc growth in DrosophilaQ47072038
Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics.Q48364922
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cellsQ50115050
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.Q52087746
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.Q52100108
Temporal trends in the incidence and survival of cancers of the upper aerodigestive tract in Ontario and the United States.Q53386271
Head and neck cancerQ54152939
Cytoplasmic YAP expression is associated with prolonged survival in patients with lung adenocarcinomas and epidermal growth factor receptor tyrosine kinase inhibitor treatment.Q54356882
Head and neck cancerQ70522684
P433issue67
P407language of work or nameEnglishQ1860
P304page(s)111130-111143
P577publication date2017-11-27
P1433published inOncotargetQ1573155
P1476titleClinical significance of YAP1 activation in head and neck squamous cell carcinoma
P478volume8

Reverse relations

cites work (P2860)
Q92821373Adaptive Responses to Monotherapy in Head and Neck Cancer: Interventions for Rationale-Based Therapeutic Combinations
Q92715223Expression of glucose transporter-1, hypoxia inducible factor-1α and beclin-1 in head and neck cancer and their implication
Q91808467Hippo Pathway and YAP Signaling Alterations in Squamous Cancer of the Head and Neck
Q96576943Targeting the Hippo pathway in cancer, fibrosis, wound healing and regenerative medicine
Q98784904The potential role of YAP in head and neck squamous cell carcinoma
Q92627373Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1
Q90613256YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma
Q91591189[Identification of differentially expressed genes between lung adenocarcinoma and squamous cell carcinoma using transcriber signature analysis]
Q92590225miR-506 is a YAP1-dependent tumor suppressor in laryngeal squamous cell carcinoma

Search more.