Dopamine in the mesolimbic system of the rat brain: endogenous levels and the effects of drugs on the uptake mechanism and stimulation of adenylate cyclase activity

scientific article published in February 1974

Dopamine in the mesolimbic system of the rat brain: endogenous levels and the effects of drugs on the uptake mechanism and stimulation of adenylate cyclase activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.1974.TB11589.X
P698PubMed publication ID4829953

P2093author name stringMiller RJ
Cuello AC
Horn AS
P2860cites workRole of the tuberculum olfactorium in stereotyped behaviour induced by apomorphine in the ratQ28249465
A protein binding assay for adenosine 3':5'-cyclic monophosphateQ33703192
Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the "dopamine receptor".Q34721196
Catecholamines in the brain as mediators of amphetamine psychosisQ39895896
Antiparkinsonian drugs: inhibition of dopamine uptake in the corpus striatum as a possible mechanism of actionQ41521409
Dopamine receptor blockade--a central action of chlorpromazine on striatal neurones.Q42439044
Uptake of (3H)-catecholamines by homogenates of rat corpus striatum and cerebral cortex: effects of amphetamine analoguesQ42440301
Catecholamines in the Median Eminence: New Evidence for a Major Noradrenergic InputQ48650985
Amphetamine psychosis: a "model" schizophrenia mediated by catecholaminesQ48706445
Behavioural and biochemical comparison of amphetamine derivatives, cocaine, benztropine and tricyclic anti-depressant drugsQ48777635
Evidence for dopamine receptor stimulation by apomorphine.Q51208002
The induction and antagonism of central nervous system stimulant-induced stereotyped behavior in the catQ52734754
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectdopamineQ170304
P304page(s)265-270
P577publication date1974-02-01
P1433published inJournal of NeurochemistryQ6295643
P1476titleDopamine in the mesolimbic system of the rat brain: endogenous levels and the effects of drugs on the uptake mechanism and stimulation of adenylate cyclase activity
P478volume22

Reverse relations

cites work (P2860)
Q360966943,4-dihydroxyphenylacetic acid (DOPAC) and the rat mesolimbic dopaminergic pathway: drug effects and evidence for somatodendritic mechanisms
Q40688370A common uptake system for serotonin and dopamine in human platelets
Q28643908A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions
Q67369785A functional effect of dopamine in the nucleus accumbens and in some other dopamine-rich parts of the rat brain
Q39995099A noradrenaline sensitive adenylate cyclase in the rat limbic forebrain: Preparation, properties and the effects of agonists, adrenolytics and neuroleptic drugs
Q48497944Adenosine 3',5'-monophosphate content in rat caudate nucleus: demonstration of dopaminergic and adrenergic receptors
Q40287147Adenosine 3′:5′-monophosphate-dependent in vitro phosphorylation of synaptosomal membrane proteins from rat corpus striatum following systemic administration of L-DOPA and bromocriptine
Q38034570Agents acting on central dopamine receptors
Q48440490Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum
Q21262022Amphetamine and pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats
Q67438774Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine
Q37796814Anti-schizophrenic drugs—Membrane receptor sites of action
Q39099099Antipsychotic phenothiazine drugs and the significance of the X-ray structure of promazine HCl
Q48464808Behavioral effects of local injection of 6-hydroxydopamine in the medial ventral tegmentum in the rat. Possible role of the mesolimbic dopaminergic system
Q49090583Behavioural effects of electrolytic and 6-hydroxydopamine lesions of the accumbens and caudate-putamen nuclei
Q67300699Behavioural supersensitivity to apomorphine following cerebral dopaminergic denervation by 6-hydroxydopamine
Q40321828Blockade by pimozide of a noradrenaline sensitive adenylate cyclase in the limbic forebrain: possible role of limbic noradrenergic mechanisms in the mode of action of antipsychotics
Q48189119Blockade of cannabinoid receptors by SR141716 selectively increases Fos expression in rat mesocorticolimbic areas via reduced dopamine D2 function
Q48472816Brain and caudate nucleus adenylate cyclase: Effects of dopamine, GTP, E prostaglandins and morphine
Q72441854Brain neurotransmitter system and chronic lead intoxication
Q40680008Catecholamine innervation of the basal forebrain III. Olfactory bulb, anterior olfactory nuclei, olfactory tubercle and piriform cortex
Q39644746Catecholamine-sensitive adenylate cyclases in nervous tissues
Q39776943Catecholamines and self-stimulation: Evidence suggesting a reinforcing role for noradrenaline and a motivating role for dopamine
Q48455421Catecholamines and self-stimulation: pharmacological differences between near- and far-lateral hypothalamic sites
Q70937224Changes in catecholamine neuronal uptake and receptor binding in the brains of spontaneously hypertensive rats (SHR)
Q43771109Changes in mesocorticolimbic dopamine and D1/D2 receptor levels after low level lead exposure: a time course study
Q40327133Characterization of a dopamine-sensitive adenylate cyclase in the rat caudate nucleus
Q71716629Characterization of stereospecific binding of 3H-(-) sulpiride, a selective antagonist at dopamine-D2 receptors, in rat CNS
Q43632484Chronic low-dose haloperidol effects on self-stimulation rate-intensity functions
Q36097007Clonidine distribution in the rat: temporal relationship between tissue levels and blood pressure response
Q48151629Clozapine decreases neuropeptide Y-like immunoreactivity and neuropeptide Y mRNA levels in rat nucleus accumbens
Q51743119Cocaine produces locomotor stimulation in SS but not LS mice: relationship to dopaminergic function.
Q45095406Cocaine produces low dose locomotor depressant effects in mice
Q66986022Comparison of dopamine synthesis regulation in the terminals of nigrostriatal, mesolimbic, tuberoinfundibular and tuberohypophyseal neurons
Q45769870Comparison of the effects of three indirect dopamine agonists, GK 13, GBR 12783 and dexamphetamine on behavioural tests involving central catecholaminergic transmissions
Q48477284Determination of nanogram amounts of homovanillic acid in the central nervous system with a rapid semiautomated fluorometric method
Q66939988Determination of picogram levels of brain serotonin by a simplified liquid chromatographic electrochemical detection assay
Q39123377Dexclamol: Effects on catecholamine metabolism and demonstration of stereochemical specificity of antagonism of central adrenergic receptors
Q67452664Differential drug effects on dopamine concentrations and rates of turnover in the median eminence, olfactory tubercle and corpus striatum
Q49153271Differential effects of (+)-amphetamine, methylphenidate, and amfonelic acid on catecholamine synthesis in selected regions of the rat brain
Q43785656Differential effects of d- and l-propranolol on dopamine turnover stimulated by oxotremorine in striatal and mesolimbic areas of rat brain
Q48244802Differential regional development of tolerance to increase in dopamine turnover upon repeated neuroleptic administration
Q44189362Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration
Q39205258Direct effect of a nomifensine derivative on dopamine receptors
Q39251718Dissociation between the presynaptic dopamine-sensitive adenylate cyclase and [3H]spiperone binding sites in rat substantia nigra
Q66986017Dopa accumulation is a measure of dopamine synthesis in the median eminence and posterior pituitary
Q69000263Dopamine D-2 receptors inhibit D-1 stimulated cyclic AMP accumulation in striatum but not limbic forebrain
Q39078920Dopamine Receptors in the Brain
Q48411487Dopamine agonist-induced stereotypic grooming and self-mutilation following striatal dopamine depletion
Q48445388Dopamine and norepinephrine levels in the nucleus accumbens, olfactory tubercle and corpus striatum following lesions in the ventral tegmental area
Q66706106Dopamine and schizophrenia
Q41648418Dopamine metabolism and receptor function after acute and chronic ethanol
Q48440108Dopamine receptor binding: Differentiation of agonist and antagonist states with 3H-dopamine and 3H-haloperidol
Q40334162Dopamine receptor blockade and the neuroleptics, a crystallographic study
Q48243762Dopamine receptor sensitivity in brain and retina of rats during aging
Q36992794Dopamine receptors and sleep induction in man
Q39160956Dopamine receptors in rat striatum and nucleus accumbens; conformational studies using rigid analogues of dopamine
Q40190461Dopamine receptors in the central thermoregulatory pathways of the rat
Q40004311Dopamine-Sensitive Adenylate Cyclase Occurs in a Region of Substantia Nigra Containing Dopaminergic Dendrites
Q48460703Dopamine-like effects of cholera toxin in the central nervous system
Q39917087Effect of butaclamol and its enantiomers upon striatal homovanillic acid and adenyl cyclase of olfactory tubercle in rats
Q40327303Effect of butaclamol on dopamine-sensitive adenylate cyclase in the rat striatum
Q40921049Effect of haloperidol and d-amphetamine on cerebral tyramine and octopamine levels
Q48246553Effect of morphine on dopamine-sensitive adenylate cyclase activity of nucleus accumbens
Q67298475Effect of suloctidil on dopaminergic transmission in various rat brain areas: possible uses as drug for the elderly
Q48260725Effects of acute or long-term treatment with chlorpromazine, haloperidol or sulpiride on neuropeptide Y-like immunoreactivity concentrations in the nucleus accumbens of rat.
Q67832575Effects of ageing on the content in sulfur-containing amino acids in rat brain
Q48965246Effects of amantadine on dopaminergic neurons in discrete regions of the rat brain
Q66961741Effects of antagonists upon locomotor stimulation induced by injection of dopamine and noradrenaline into the nucleus accumbens of nialamide-pretreated rats
Q39182847Effects of bromocriptine on adenylate cyclase and phosphodiesterase activities of rat striatum
Q39082676Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity
Q48538541Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography
Q44361744Effects of haloperidol and clozapine on neuropeptide Y-like immunoreactivity in the nucleus accumbens and striatum of rats pretreated with psychostimulants
Q48626391Effects of morphine on dopamine metabolism in rat striatum and limbic structures in relation to the activity of dopaminergic neurones
Q43764321Effects of psychological stress on monoamine systems in subregions of the frontal cortex and nucleus accumbens of the rat.
Q39209458Effects on striatal and mesolimbic dopamine systems of a new potential antipsychotic drug -mezilamine- with weak cataleptogenic properties
Q41537141Electrophysiological responses of neurones in the nucleus accumbens to hippocampal stimulation and the attenuation of the excitatory responses by the mesolimbic dopaminergic system
Q67342377Enhancement of apomorphine-induced inhibition of vocalisation afterdischarge response by theophylline
Q35128079Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate after lesions in substantia nigra: evidence for denervation supersensitivity
Q40325029Enzymatic evidence for a meso-limbic dopaminergic innervation in the olfactory tubercle of the rabbit
Q44063639Functional and autoradiographic characterization of dopamine D2-like receptors in the guinea pig heart
Q70911665Gas chromatographic determination of some biogenic amines as their pentafluorobenzoyl derivatives in the picogram range and its applicability to biological materials
Q39156108Guanylate cyclase activity in various rat brain areas
Q38789379Heterogeneous extracellular dopamine regulation in the subregions of the olfactory tubercle.
Q72421023In vivo blockade of dopaminergic receptors from different rat brain regions by classical and atypical neuroleptics
Q51720769Inbred rat strain comparisons indicate different sites of action for cocaine and amphetamine locomotor stimulant effects
Q67269267Increase in brain 125I-cholecystokinin (CCK) receptor binding following chronic haloperidol treatment, intracisternal 6-hydroxydopamine or ventral tegmental lesions
Q40164529Increase in dopamine in cerebral cortex and other regions of rat brain after microwave fixation: possible diffusion artifact
Q39743126Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain
Q52248666Influence of the D-2 dopamine receptor agonist quinpirole on the odor detection performance of rats before and after spiperone administration.
Q48333613Influence of typical and atypical antipsychotics on neuropeptide Y-like immunoreactivity and NPY mRNA expression in rat striatum
Q66898486Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat
Q41733960Interaction of sulpiride and ergot derivatives on rat brain DOPAC concentration and prolactin secretion in vivo
Q49092294Interactions of a neuroleptic drug (fluphenazine) with catecholamines in hippocampus
Q35028210L-3,4-dihydroxyphenylalanine-induced hypersensitivity simulating features of denervation
Q39936303LSD and dopamine-sensitive adenylate-cyclase in various rat brain areas
Q66921709Lack of a high affinity transport system for dopamine in the median eminence and posterior pituitary
Q48387620Lesions of ascending dopaminergic pathways decrease forebrain glucose uptake
Q40652109Localization of GABAergic, cholinergic and aminergic structures in the mesolimbic system
Q39149367Localization of Nigral Dopamine-Sensitive Adenylate Cyclase on Neurons Originating from the Corpus Striatum
Q39099094Localization of dopamine receptors in the rat cerebral cortex
Q41690441Localization of glutamic acid decarboxylase within laminae of the rat olfactory tubercle
Q40348571Locomotor activity stimulation in rats produced by dopamine in the nucleus accumbens: potentiation by caffeine
Q48679942Manipulation of mobile phase parameters for the HPLC separation of endogenous monoamines in rat brain tissue
Q41359421Mesolimbic dopamine neurons: Effects of 6-hydroxydopamine-induced destruction and receptor blockade on drug-induced rotation of rats
Q39298281Mesolimbic dopaminergic neurones and somatodendritic mechanisms
Q44263622Mesolimbic dopaminergic neurones in the rotational model of nigrostriatal function
Q71512333Morphine differentially alters synthesis and turnover of dopamine in central neuronal systems
Q48198822Motor activity of rats following intracerebral injections of drugs influencing GABA mechanisms
Q66959814Muscarinic cholinergic binding in striatal and mesolimbic areas of the rat: Reduction by 6-hydroxydopa
Q39673815Naloxone antagonizes theophylline-induced potentiation of morphine inhibition of a nociceptive reaction in rats
Q48882530Neurochemical Studies of the Mesolimbic Dopaminergic Pathway: [3H]Spiperone Labels Two Binding Sites in Homogenates of the Nucleus Accumbens of Rat Brain
Q66706108Neuromuscular transmission in asthma
Q66898482Nomifensine: A potent dopaminergic agonist of antiparkinson potential
Q48646647Non-DA prefronto-cortical efferents modulate D1 receptors in the nucleus accumbens
Q67440453Norepinephrine-epinephrine and serotonin content of nasal mucosa in relation to hemorrhage, reserpine and excitement
Q40118821Normal and abnormal determinants of dopamine receptor ontogeny in the central nervous system
Q48260989Odor detection performance of rats following d-amphetamine treatment: a signal detection analysis
Q66852521On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain
Q40031471On the structural requirements for dopamine-like activity in homogenates of rat nucleus accumbens [proceedings]
Q40030053Ontogenesis of the multiple forms of choline acetyltransferase: uptake and acetylation of choline in rat brain [proceedings]
Q48371944Ontogenetic development of neostriatal dopamine receptors in the rat.
Q39773343Pharmacology and Neurochemistry of Apomorphine
Q28138954Psychopharmacological studies on (-)-nuciferine and its Hofmann degradation product atherosperminine
Q35013822Quantitative correlation of dopamine-dependent adenylate cyclase with responses to levodopa in various mice
Q64986355Rat climbing behavior elicited by stimulation of cerebral dopamine receptors.
Q48830098Regional distribution of sultopride and sulpiride in rat brain measured by radioimmunoassay
Q39159387Regional effects of neuroleptics of dopamine metabolism and dopamine-sensitive adenylate cyclase activity
Q39212809Regional localization of halopemide, a new psychotropic agent, in the rat brain
Q39128853Single and repeated administration of neuroleptic drugs to rats: Effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-dopa
Q48941510Species Differences in the Brain Regional Distribution of Receptor Binding for Thyrotropin-Releasing Hormone
Q40047537Specificity of 6-hydroxydopamine-induced destruction of mesolimbic or nigrostriatal dopamine-containing terminals
Q43828208Stereoselective effects of the potentially neuroleptic rigid spiro amines
Q39096659Stimulation of tyrosine hydroxylase activity by cyclic amp in synaptosomes and in soluble striatal enzyme preparations
Q40161727Structural and steric requirements for ?-phenethylamines as agonists of the noradrenergic cyclic AMP generating system in the rat limbic forebrain
Q39999834Studies on the behavioural pharmacology of a cyclic analogue of dopamine following its injection into the brains of conscious rats
Q48382598Substantia nigra of the rat contains a dopamine sensitive adenylate cyclase
Q39969560Sulpiride: A study of the effects on dopamine receptors in rat neostriatum and limbic forebrain
Q38003131The Formation, Degradation, and Function of Cyclic Nucleotides in the Nervous System
Q37369100The Role of Cyclic Nucleotides in the CNS
Q40229404The behavioral effects of D-amphetamine are correlated with its effects on cAMP in different brain regions
Q48529559The conformation of dopamine at its uptake site; further studies with rigid analogues
Q39999711The interaction of neuroleptic and muscarinic agents with central dopaminergic systems
Q39104562The nature of receptors regulating the formation of cyclic AMP in brain tissue
Q41034664The nucleus accumbens–possible site of antipsychotic action of neuroleptic drugs?
Q39278128The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: Metoclopramide, thiethylperazine, and molindone as pharmacological tools
Q28339708Time-dependent effects of phenothiazines on dopamine turnover in psychiatric patients
Q71578698Type A monoamine oxidase catalyzes the intraneuronal deamination of dopamine within nigrostriatal, mesolimbic, tuberoinfundibular and tuberohypophyseal neurons in the rat
Q44761069Unilateral 6-hydroxydopamine lesions of nigrostriatal or mesolimbic dopamine-containing terminals and the drug-induced rotation of rats
Q49830688iTRAQ-based quantitative proteomic analysis reveals important metabolic pathways for arsenic-induced liver fibrosis in rats.

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