The constriction and scission machineries involved in mitochondrial fission

scientific article published on 25 August 2017

The constriction and scission machineries involved in mitochondrial fission is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/JCS.199562
P698PubMed publication ID28842472

P50authorMichael T RyanQ37381043
Felix KrausQ41291532
P2860cites workDynamin-related protein Drp1 is required for mitochondrial division in mammalian cellsQ24291591
MiD49 and MiD51, new components of the mitochondrial fission machineryQ24300113
Direct dynamin-actin interactions regulate the actin cytoskeletonQ24302210
A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosisQ24306318
Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fissionQ24307570
An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2Q24311384
The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cellsQ24312865
Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cellsQ24315625
Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fissionQ24315659
SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycleQ24318317
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondriaQ24320227
Bax activates endophilin B1 oligomerization and lipid membrane vesiculationQ24322581
Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fissionQ24336802
Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scissionQ24337363
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like proteinQ24338467
Fission and selective fusion govern mitochondrial segregation and elimination by autophagyQ24652230
The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domainQ24653611
Endophilin B1 is required for the maintenance of mitochondrial morphologyQ24678157
Metabolic regulation of mitochondrial dynamicsQ26768130
Mitochondrial form and functionQ26866448
Coupling between clathrin-coated-pit invagination, cortactin recruitment, and membrane scission observed in live cellsQ42814516
Dynamin undergoes a GTP-dependent conformational change causing vesiculationQ47945531
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission.Q50769548
Lethal Disorder of Mitochondrial Fission Caused by Mutations in DNM1L.Q51551241
Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.Q53548157
New insights into the function and regulation of mitochondrial fissionQ27010550
Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathyQ27309059
Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stressQ27330478
The crystal structure of dynaminQ27674161
The Mitochondrial Fission Receptor MiD51 Requires ADP as a CofactorQ27681635
A Dynamin Mutant Defines a Superconstricted Prefission StateQ27684922
Dnm1 forms spirals that are structurally tailored to fit mitochondriaQ27930356
Mdv1 interacts with assembled dnm1 to promote mitochondrial divisionQ27933197
A role for the dynamin-like protein Vps1 during endocytosis in yeastQ27939694
Membrane fission by dynamin: what we know and what we need to knowQ28080135
Tau promotes neurodegeneration via DRP1 mislocalization in vivoQ28119104
Dynamin-like protein 1 is involved in peroxisomal fissionQ28218956
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fissionQ28235694
Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth diseaseQ28236802
Mechanistic analysis of a dynamin effectorQ28254951
Mutations in dynamin 2 cause dominant centronuclear myopathyQ28277269
Specific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1Q28390513
Mitochondrial division and fusion in metabolismQ28390964
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fissionQ28854266
Generation of high curvature membranes mediated by direct endophilin bilayer interactionsQ29616512
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injuryQ29616550
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.Q29616569
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in miceQ29617092
ER tubules mark sites of mitochondrial divisionQ29619991
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell deathQ29620448
An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recyclingQ30155920
Regulating actin dynamics at membranes: a focus on dynaminQ30433704
Constriction and Dnm1p recruitment are distinct processes in mitochondrial fissionQ30478325
Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission-fusion balance within mitochondrial networksQ30819969
Actin filaments as dynamic reservoirs for Drp1 recruitmentQ30822185
A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission.Q33747119
Mammalian dynamin-like protein DLP1 tubulates membranesQ33946794
Novel roles for actin in mitochondrial fissionQ34433432
Structure and function of ER membrane contact sites with other organellesQ34503783
Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fissionQ34825960
Membrane shape at the edge of the dynamin helix sets location and duration of the fission reactionQ34915566
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvationQ35064216
Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1.Q35158361
Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.Q35165455
Shaping the dynamic mitochondrial networkQ35177854
A hemi-fission intermediate links two mechanistically distinct stages of membrane fissionQ35929056
Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damageQ35962319
A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division.Q36071398
Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity.Q36419300
Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 proteinQ36463355
Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sitesQ36585866
Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodelingQ36634699
DNM1L-related mitochondrial fission defect presenting as refractory epilepsyQ37351458
The dynamin-related GTPase Drp1 is required for embryonic and brain development in miceQ37365414
GTPase cycle of dynamin is coupled to membrane squeeze and release, leading to spontaneous fissionQ37401393
A role for myosin II in mammalian mitochondrial fissionQ37645544
Dynamin 2 and human diseases.Q37686342
Novel regulatory roles of Mff and Drp1 in E3 ubiquitin ligase MARCH5-dependent degradation of MiD49 and Mcl1 and control of mitochondrial dynamicsQ37686829
Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1Q37774674
Peripheral neuropathy in mitochondrial disordersQ38139602
Lipids of mitochondriaQ38148540
Splitting up the powerhouse: structural insights into the mechanism of mitochondrial fissionQ38522735
Mito-Morphosis: Mitochondrial Fusion, Fission, and Cristae Remodeling as Key Mediators of Cellular FunctionQ38669205
Multiple dynamin family members collaborate to drive mitochondrial divisionQ38734892
ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cellsQ38758060
Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission.Q38778376
The mitochondria-endoplasmic reticulum contact sites: a signalling platform for cell deathQ39229178
Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.Q39689532
A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosisQ39752213
Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy.Q39985951
Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division.Q41123546
Three-dimensional reconstruction of dynamin in the constricted stateQ41630749
The coexistence of dynamin 2 mutation and multiple mitochondrial DNA (mtDNA) deletions in the background of severe cardiomyopathy and centronuclear myopathyQ41708445
A lethal defect of mitochondrial and peroxisomal fissionQ41918612
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectmitochondrial fissionQ6881852
P304page(s)2953-2960
P577publication date2017-08-25
P1433published inJournal of Cell ScienceQ1524177
P1476titleThe constriction and scission machineries involved in mitochondrial fission
P478volume130

Reverse relations

cites work (P2860)
Q60143780Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology
Q83227596Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division
Q91260354Completion of BAX recruitment correlates with mitochondrial fission during apoptosis
Q96306249Concerted Action of AMPK and Sirtuin-1 Induces Mitochondrial Fragmentation Upon Inhibition of Ca2+ Transfer to Mitochondria
Q94464358Distinct Contributions of the Peroxisome-Mitochondria Fission Machinery During Sexual Development of the Fungus Podospora anserina
Q90206029Divide et Impera: Drp1-mediated Mitochondrial Fission in Glioma Malignancy
Q91942098Do You Remember Mitochondria?
Q99350201Drp1-dependent mitochondrial fission in cardiovascular disease
Q92711423Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis
Q91821455Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice
Q100958707Dynamin-2 R465W mutation induces long range perturbation in highly ordered oligomeric structures
Q59790653Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission
Q58089952Geometric instability catalyzes mitochondrial fission
Q47224372Highlighting the Endoplasmic Reticulum-Mitochondria connection: focus on Mitofusin 2.
Q64056295Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery
Q49683763Inactivation of cardiolipin synthase triggers changes in mitochondrial morphology
Q100385812Increased long noncoding RNA maternally expressed gene 3 contributes to podocyte injury induced by high glucose through regulation of mitochondrial fission
Q90709145Interplay of mitochondrial fission-fusion with cell cycle regulation: Possible impacts on stem cell and organismal aging
Q89531374Listeria monocytogenes Exploits Mitochondrial Contact Site and Cristae Organizing System Complex Subunit Mic10 To Promote Mitochondrial Fragmentation and Cellular Infection
Q90260807Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics
Q64067141Mitochondrial Morphofunction in Mammalian Cells
Q90374857Mitochondrial dynamics: overview of molecular mechanisms
Q83226423Neurotrophins induce fission of mitochondria along embryonic sensory axons
Q91885312Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice
Q90364813Peroxisome biogenesis, membrane contact sites, and quality control
Q47654464Reactive Oxygen Species and Mitochondrial Dynamics: The Yin and Yang of Mitochondrial Dysfunction and Cancer Progression
Q92113005Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning
Q91961627Role of Cardiolipin in Mitochondrial Function and Dynamics in Health and Disease: Molecular and Pharmacological Aspects
Q64762196Role of GTPases in the regulation of mitochondrial dynamics in Parkinson's disease
Q64068837STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism
Q59088229Structural basis of mitochondrial receptor binding and constriction by DRP1
Q92969123The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy
Q64777663The Shape of Mitochondrial Dysfunction in Down Syndrome
Q89900069The anti-viral dynamin family member MxB participates in mitochondrial integrity
Q103746777The effect of autophagy and mitochondrial fission on Harderian gland is greater than apoptosis in male hamsters during different photoperiods
Q90167389The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria

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