Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications

scientific article published in August 1987

Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1126/SCIENCE.3299709
P698PubMed publication ID3299709

P50authorStephen L. HoffmanQ60231547
P2093author name stringChulay JD
Hollingdale MR
Wirtz RA
Plowe CV
Beier JC
Oster CN
Mugambi M
Woollett GR
P433issue4815
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
antibodyQ79460
malaria vaccineQ6741353
vaccineQ134808
malaria preventionQ93598033
P1104number of pages4
P304page(s)639-642
P577publication date1987-08-01
P1433published inScienceQ192864
P1476titleNaturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications
P478volume237

Reverse relations

cites work (P2860)
Q48002588'Original antigenic sin', T cell memory, and malaria sporozoite immunity: an hypothesis for immune evasion
Q371471351 Antimalarial Activity of the 8-Aminoquinolines
Q33859633A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
Q34520456A prospective study of the association between the human humoral immune response to Plasmodium falciparum blood stage antigen gp190 and control of malarial infections.
Q53700367A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
Q44146077A rapid inhibition micro ELISA for detecting antibodies to Plasmodium falciparum sporozoites in human blood
Q46223301A theoretical framework for the immunoepidemiology of Plasmodium falciparum malaria.
Q24651173Acquired immunity to malaria
Q47879434Activity of human volunteer sera to candidate Plasmodium falciparum circumsporozoite protein vaccines in the inhibition of sporozoite invasion assay of human hepatoma cells and hepatocytes.
Q35084077Adoptive transfer of immunity to Theileria parva in the CD8+ fraction of responding efferent lymph
Q38993794Analysis of Plasmodium falciparum infections in a village community in Northern Nigeria: determination of msp2 genotypes and parasite-specific IgG responses
Q47859209Anti-circumsporozoite protein antibodies measure age related exposure to malaria in Kataragama, Sri Lanka
Q37800092Anti-sporozoite antibodies
Q92965786Antibodies against Plasmodium falciparum malaria at the molecular level
Q40484421Antibodies to the Circumsporozoite Protein and Protective Immunity to Malaria Sporozoites
Q36668494Antibody responses to Plasmodium falciparum and P. vivax sporozoites in areas with stable and unstable malaria
Q35946430Antigenic diversity and immune evasion by malaria parasites.
Q37278891Assessment of the relative success of sporozoite inoculations in individuals exposed to moderate seasonal transmission
Q40193241Characterization of antibodies to sporozoites in Plasmodium falciparum malaria and correlation with protection
Q41194352Circumsporozoite antibodies and falciparum malaria incidence in children living in a malaria endemic area
Q36366362Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity
Q41200913Comparative analysis of ELISAs employing repetitive peptides to detect antibodies to Plasmodium falciparum sporozoites
Q90300290Complement in malaria immunity and vaccines
Q30420219Controlling malaria: competition, seasonality and 'slingshotting' transgenic mosquitoes into natural populations
Q47896240Conversion of poorly immunogenic malaria repeat sequences into a highly immunogenic vaccine candidate
Q38953222Cross-stage immunity for malaria vaccine development
Q37635135Decreased growth rate of P. falciparum blood stage parasitemia with age in a holoendemic population
Q37175173Differential antibody responses to Plasmodium falciparum and P. vivax circumsporozoite proteins in a human population
Q41200573ELISA method for detecting Plasmodium falciparum circumsporozoite antibody
Q36668566Evaluation of an in vitro assay aimed at measuring protective antibodies against sporozoites
Q36668533Evidence implicating MHC genes in the immunological nonresponsiveness to the plasmodium falciparum CS protein
Q47976889Experimental asexual blood stage malaria immunity
Q33617329Expression and immune recognition of the conserved MSP4 outer membrane protein of Anaplasma marginale
Q46662804Fine epitope specificity of antibodies to region II of the Plasmodium vivax circumsporozoite protein correlates with ability to bind recombinant protein and sporozoites
Q62738086Functional antibodies against sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso
Q36674065Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells
Q33798041Hepatitis C virus infection may lead to slower emergence of P. falciparum in blood
Q36726723High road, low road? Choices and challenges on the pathway to a malaria vaccine
Q52715900Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children.
Q48028231Identification and characterization of the protective hepatocyte erythrocyte protein 17 kDa gene of Plasmodium yoelii, homolog of Plasmodium falciparum exported protein 1.
Q47904847IgM antibody responses to the circumsporozoite protein in naturally acquired falciparum malaria
Q43952848Immune responses to Plasmodium falciparum antigens during a malaria vaccine trial in Tanzanian children
Q37800091Immune responses to sporozoite antigens and their relationship to naturally acquired immunity to malaria
Q38689264Immunity to malaria in an era of declining malaria transmission
Q50041449Immunization of malaria pre-exposed volunteers with PfSPZ Vaccine elicits long-lived IgM invasion-inhibitory and complement-fixing antibodies
Q34601683Immunoglobulin G antibodies to merozoite surface antigens are associated with recovery from chloroquine-resistant Plasmodium falciparum in Gambian children
Q44172196Kinetics of expression of two major Plasmodium berghei antigens in the mosquito vector, Anopheles stephensi
Q37113126Linking environmental variability to village-scale malaria transmission using a simple immunity model
Q34028638Low doses of killed parasite in CpG elicit vigorous CD4+ T cell responses against blood-stage malaria in mice.
Q57954052Malaria diagnosis: memorandum from a WHO meeting
Q47854035Malaria. Getting into the liver
Q41739876Molecular basis for evasion of host immunity and pathogenesis in malaria
Q24798369Molecular dissection of the human antibody response to the structural repeat epitope of Plasmodium falciparum sporozoite from a protected donor
Q47864161Multiple antigen peptides for specific detection of antibodies to a malaria antigen in human sera
Q94950040OMIP-064: A 27-Color Flow Cytometry Panel to Detect and Characterize Human NK Cells and Other Innate Lymphoid Cell Subsets, MAIT Cells, and γδ T Cells
Q48021082Plasmodium berghei-specific T cells respond to non-processed sporozoites presented by B cells
Q37003064Plasmodium chabaudi malaria: protective immunization with surface membranes of infected erythrocytes.
Q34419934Plasmodium immunomics.
Q36644236Pre-erythrocytic malaria vaccines: identifying the targets
Q34521010Progress and challenges for malaria vaccines
Q35094826Protection of Malian children from clinical malaria is associated with recognition of multiple antigens
Q37241837Protective value of elevated levels of gamma interferon in serum against exoerythrocytic stages of Plasmodium falciparum
Q34264618Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine
Q38665423Rationale for the development of an engineered sporozoite malaria vaccine
Q47863358Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children
Q39075264Steps towards a malaria vaccine
Q33312392Sterile protection against malaria is independent of immune responses to the circumsporozoite protein
Q33747338The Antibody-Secreting Cell Response to Infection: Kinetics and Clinical Applications
Q36650703The circumsporozoite protein of Plasmodium: a mechanism of immune evasion by the malaria parasite?
Q40910243The development of a multivalent DNA vaccine for malaria
Q47640667The hope but challenge for developing a vaccine that might control malaria
Q37012062The immunological challenges of malaria vaccine development
Q33970972The immunology of malaria infection
Q52307983The maintenance of strain structure in populations of recombining infectious agents.
Q36668549The role of cytokines in malaria infection
Q28473729Transcriptional analysis of the pre-erythrocytic stages of the rodent malaria parasite, Plasmodium yoelii
Q36668498Use of non-human primate hepatocytes for in vitro study of the pre-erythrocytic stages of malaria parasites
Q36117148Vaccination against malaria
Q39296506Vaccines to Accelerate Malaria Elimination and Eventual Eradication
Q33587443Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model
Q37426820World Malaria Day 2009: what malaria knows about the immune system that immunologists still do not.

Search more.