A high concentration of fatty acids induces TNF-α as well as NO release mediated by the P2X4 receptor, and the protective effects of puerarin in RAW264.7 cells

scientific article published on 22 September 2017

A high concentration of fatty acids induces TNF-α as well as NO release mediated by the P2X4 receptor, and the protective effects of puerarin in RAW264.7 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/C7FO00544J
P8608Fatcat IDrelease_hbywnfaqlbbrhdatoysqta7bdq
P698PubMed publication ID28937704

P2093author name stringTao Li
Shuo Wang
Cheng-Xin Gong
Hong Xu
Lu Ding
Chao-Peng Xiong
Fang-Fang Hu
Shang-Dong Liang
Xing-Zi Liu
Yun-Ming Tu
P2860cites workStauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signallingQ47867433
High fatty acids modulate P2X(7) expression and IL-6 release via the p38 MAPK pathway in PC12 cells.Q48149917
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitisQ50452492
PGC-1β suppresses saturated fatty acid-induced macrophage inflammation by inhibiting TAK1 activation.Q53802165
The role of free fatty acids in the inflammatory and cardiometabolic profile in adolescents with metabolic syndrome engaged in interdisciplinary therapyQ57588521
Crystal structure of the ATP-gated P2X(4) ion channel in the closed stateQ24657193
The role of airway macrophages in apoptotic cell clearance following acute and chronic lung inflammationQ26767123
P2X ion channel receptors and inflammationQ28066934
Association between serum free fatty acid levels and possible related factors in patients with type 2 diabetes mellitus and acute myocardial infarctionQ34537384
Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathwayQ35016067
Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort StudyQ36081622
LncRNA NONRATT021972 siRNA attenuates P2X7 receptor expression and inflammatory cytokine production induced by combined high glucose and free fatty acids in PC12 cellsQ36863561
Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice.Q37163044
Extracellular ATP drives systemic inflammation, tissue damage and mortality.Q37680164
P2X4 receptors expressed on microglial cells in post-ischemic inflammation of brain ischemic injuryQ38184232
P2X receptors and inflammationQ38294028
Tetrandrine suppresses β‑glucan‑induced macrophage activation via inhibiting NF‑κB, ERK and STAT3 signaling pathwaysQ38774915
Macrophages in Vascular Inflammation: Origins and FunctionsQ38820074
Puerarin Suppresses Macrophage Activation via Antioxidant Mechanisms in a CaPO4-Induced Mouse Model of Aneurysm.Q38959247
Inhibition of LPS-induced TNF-α and NO production in mouse macrophage and inflammatory response in rat animal models by a novel Ayurvedic formulation, BV-9238.Q39007129
Maleylated-BSA suppresses lipopolysaccharide-induced IL-6 production by activating the ERK-signaling pathway in murine RAW264.7 cells.Q39035943
Pannexin1 contributes to pathophysiological ATP release in lipoapoptosis induced by saturated free fatty acids in liver cellsQ39279987
Upregulation of osteoblastic differentiation marker mRNA expression in osteoblast-like UMR106 cells by puerarin and phytoestrogens from Pueraria mirificaQ39285014
Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophagesQ39382408
Puerarin exerts antipyretic effect on lipopolysaccharide-induced fever in rats involving inhibition of pyrogen production from macrophagesQ39383266
Anti-inflammatory effects of short chain fatty acids in IFN-gamma-stimulated RAW 264.7 murine macrophage cells: involvement of NF-kappaB and ERK signaling pathwaysQ40197858
Extracellular ATP Induces Vascular Inflammation and Atherosclerosis via Purinergic Receptor Y2 in Mice.Q40638392
Trans-resveratrol attenuates high fatty acid-induced P2X7 receptor expression and IL-6 release in PC12 cells: possible role of P38 MAPK pathwayQ42703766
Puerarin ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney through ERK/Nrf2/ARE pathwayQ42704998
Homocysteine modifies extracellular ATP availability in macrophagesQ42709314
Inhibition of P2X4 suppresses joint inflammation and damage in collagen-induced arthritisQ43764987
Puerarin Exerts an Antiinflammatory Effect by Inhibiting NF-kB and MAPK Activation in Staphylococcus aureus-Induced MastitisQ44123813
Chronic exposure to high glucose impairs bradykinin-stimulated nitric oxide production by interfering with the phospholipase-C-implicated signalling pathway in endothelial cells: evidence for the involvement of protein kinase C.Q45232442
Activation of human alveolar macrophages via P2 receptors: coupling to intracellular Ca2+ increases and cytokine secretionQ46473137
Effect of pecan phenolics on the release of nitric oxide from murine RAW 264.7 macrophage cellsQ46523737
ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathyQ46577083
Beneficial effects of evodiamine on P2X(4)-mediated inflammatory injury of human umbilical vein endothelial cells due to high glucose.Q46673565
P433issue12
P304page(s)4336-4346
P577publication date2017-09-22
P1433published inFood & FunctionQ3076426
P1476titleA high concentration of fatty acids induces TNF-α as well as NO release mediated by the P2X4 receptor, and the protective effects of puerarin in RAW264.7 cells
P478volume8

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cites work (P2860)
Q60955668Cardioprotective Effects of Puerarin-V on Isoproterenol-Induced Myocardial Infarction Mice Is Associated with Regulation of PPAR-Υ/NF-κB Pathway
Q61814061Elevated free fatty acid level is associated with insulin-resistant state in nondiabetic Chinese people

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