Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice.

scientific article published on 23 July 2013

Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPENDO.00263.2013
P698PubMed publication ID23880317
P5875ResearchGate publication ID251568741

P50authorDavid HandelsmanQ42290742
Jeremy T. SmithQ45933621
Kirsty WaltersQ63364185
P2093author name stringGuang Ning
Charles M Allan
Mark Jimenez
Reena Desai
Linda J Middleton
Shai R Joseph
Xiaobing B Cheng
P2860cites workCloning of Human Androgen Receptor Complementary DNA and Localization to the X ChromosomeQ28118052
Kisspeptin signaling in the brainQ28259280
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cellsQ29614542
Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorderQ30312183
Androgens increase gonadotropin-releasing hormone neuron firing activity in females and interfere with progesterone negative feedbackQ30438916
Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axisQ30444265
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry assay to simultaneously measure androgens and estrogens in serum without derivatizationQ33443584
Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout modelsQ34021641
Premature ovarian failure in androgen receptor-deficient miceQ34248205
Contributions of androgen and estrogen to fetal programming of ovarian dysfunction.Q34512436
Regulation of the neuroendocrine reproductive axis by kisspeptin-GPR54 signaling.Q34652017
Androgen actions and the ovaryQ37001151
Subfertile female androgen receptor knockout mice exhibit defects in neuroendocrine signaling, intraovarian function, and uterine development but not uterine function.Q37244723
Androgens stimulate early stages of follicular growth in the primate ovaryQ37383118
Subfertility and defective folliculogenesis in female mice lacking androgen receptorQ37388507
Oestrogen, kisspeptin, GPR54 and the pre-ovulatory luteinising hormone surge.Q37389838
Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5alpha-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neuronsQ41061349
The estradiol-induced surge of gonadotropin-releasing hormone in the ewe.Q41205292
New concepts of the neuroendocrine regulation of gonadotropin surges in ratsQ41442568
Effects of Exogenous Testosterone on Ovarian Weight, Follicular Morphology and Intraovarian Progesterone Concentration in Estrogen-Primed Hypophysectomized Immature Female RatsQ41669841
Effect of adrenal and ovarian androgens on type 4 follicles unresponsive to FSH in immature miceQ42511598
Measurement of sex steroids in murine blood and reproductive tissues by liquid chromatography-tandem mass spectrometry.Q43166996
Increased ovulation rate in gilts treated with dihydrotestosteroneQ43932914
Ovarian follicle development requires Smad3.Q44932568
Androgen receptor mRNA is inversely regulated by testosterone and estradiol in adult mouse brainQ44948604
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.Q46407047
Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouseQ46438750
Androgen receptor mRNA expression in the bovine ovaryQ47440705
Acute modulation of the hypothalamic-pituitary axis by intravenous testosterone in normal womenQ48272295
Gonadotropin-releasing hormone surge in pro-oestrous rats.Q48344685
Kiss1 neurons in the forebrain as central processors for generating the preovulatory luteinizing hormone surge.Q48489842
Preweaning over- and underfeeding alters onset of puberty in the rat without affecting kisspeptin.Q48634870
Targeted loss of androgen receptor signaling in murine granulosa cells of preantral and antral follicles causes female subfertilityQ48637116
Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility.Q48794224
Immunohistochemical Localization of the Androgen Receptor in Rat and Human Tissues*Q48857175
Androgens promote oocyte insulin-like growth factor I expression and initiation of follicle development in the primate ovaryQ48912949
The effect of testosterone on the maturation and developmental capacity of murine oocytes in vitroQ49040601
Methods for quantifying follicular numbers within the mouse ovary.Q50675271
Androgen/androgen receptor pathway regulates expression of the genes for cyclooxygenase-2 and amphiregulin in periovulatory granulosa cells.Q51273212
Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.Q51356918
Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys.Q51706747
Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model.Q51829719
Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strainQ52099750
Developmental regulation of androgen receptor in rat ovaryQ52208064
Serum Steroid Levels During the Menstrual Cycle in a Bilaterally Adrenalectomized WomanQ56004204
Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone NeuronsQ56030090
P433issue6
P304page(s)E717-26
P577publication date2013-07-23
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleCharacterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice
P478volume305

Reverse relations

cites work (P2860)
Q487682754-Methylcatechol inhibits cell growth and testosterone production in TM3 Leydig cells by reducing mitochondrial activity.
Q30370718Conditional knockout of the androgen receptor in gonadotropes reveals crucial roles for androgen in gonadotropin synthesis and surge in female mice.
Q28277829Effects of melatonin on oocyte maturation in PCOS mouse model
Q36323832Gonadotropin-releasing hormone receptor (Gnrhr) gene knock out: Normal growth and development of sensory, motor and spatial orientation behavior but altered metabolism in neonatal and prepubertal mice
Q30370622Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice
Q50554013High levels of testosterone inhibit ovarian follicle development by repressing the FSH signaling pathway.
Q42290703Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.
Q42290715Neuronal androgen receptor: Molecular gateway to polycystic ovary syndrome?
Q44946395The Steroid Metabolome in the Isolated Ovarian Follicle and Its Response to Androgen Exposure and Antagonism
Q55278835Zebrafish androgen receptor is required for spermatogenesis and maintenance of ovarian function.

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