CYP3A5*3 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients

scientific article published on 17 December 2013

CYP3A5*3 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCPH.230
P698PubMed publication ID24214410

P50authorRichie SoongQ39459426
P2093author name stringNur Sabrina Sapari
Boon-Cher Goh
Gaik Hong Soon
Kok-Yong Seng
Lawrence Soon-U Lee
Kim-Hor Hee
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Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolamQ28305304
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Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probesQ33914036
A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic modelQ34337705
The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA PerspectiveQ35129048
Phenotyping CYP3A using midazolam in cancer and noncancer Asian patientsQ35825212
Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients.Q35825944
Prolonged sedation due to accumulation of conjugated metabolites of midazolamQ42276898
Importance of shrinkage in empirical bayes estimates for diagnostics: problems and solutionsQ42578169
Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7.Q42936096
Pharmacokinetics of midazolam in CYP3A4- and CYP3A5-genotyped subjectsQ44870135
CYP3A5 genotype and midazolam clearance in Australian patients receiving chemotherapy.Q44922994
Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltrationQ45247227
Genotype-phenotype associations of cytochrome P450 3A4 and 3A5 polymorphism with midazolam clearance in vivoQ46496009
Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomesQ46903207
A size standard for pharmacokinetics.Q47332170
Factors affecting cytochrome P-450 3A activity in cancer patients.Q47873497
Impact of the CYP3A5 genotype on midazolam pharmacokinetics and pharmacodynamics during intensive care sedationQ48567513
Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes.Q48589806
Ketoconazole renders poor CYP3A phenotype status with midazolam as probe drugQ48706686
Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.Q51635996
Clinical pharmacokinetics of midazolam in intensive care patients, a wide interpatient variability?Q51774518
Failure of critically ill patients to metabolise midazolam.Q51789578
The pharmacokinetics of midazolam in man.Q51868900
Akaike's information criterion in generalized estimating equations.Q52066951
P433issue2
P921main subjectpharmacokineticsQ323936
midazolamQ423071
P304page(s)215-224
P577publication date2013-12-17
P1433published inThe Journal of Clinical PharmacologyQ7743562
P1476titleCYP3A5*3 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients
P478volume54

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cites work (P2860)
Q91585715Effects of Vitamin D Receptor, Cytochrome P450 3A, and Cytochrome P450 Oxidoreductase Genetic Polymorphisms on the Pharmacokinetics of Remimazolam in Healthy Chinese Volunteers
Q42204826Effects of cytochrome P450 family 3 subfamily A member 5 gene polymorphisms on daunorubicin metabolism and adverse reactions in patients with acute leukemia
Q35903844Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRI
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Q47213395The pharmacogenetics of medications used in general anesthesia