A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1.

scientific article published on 9 August 2017

A diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.201704056
P932PMC publication ID5584182
P698PubMed publication ID28794127

P50authorVivek MalhotraQ39199774
David Cruz-GarcíaQ59688805
Gabriel MoraQ81113543
P2093author name stringNathalie Brouwers
Juan M Duran
Amy J Curwin
P2860cites workNucleotide sequence of human monocyte interleukin 1 precursor cDNAQ24605740
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal OmegaQ27860809
Quality control of inner nuclear membrane proteins by the Asi complexQ27932769
Unconventional secretion of Acb1 is mediated by autophagosomes.Q27934275
A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettesQ28131622
Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expressionQ28215218
Enzymatic assembly of DNA molecules up to several hundred kilobasesQ28241142
Evidence of calcium- and SNARE-dependent release of CuZn superoxide dismutase from rat pituitary GH3 cells and synaptosomes in response to depolarizationQ28566100
Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosisQ28592161
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1βQ29030555
Presenting your structures: the CCP4mg molecular-graphics softwareQ29547443
Rapid and reliable protein extraction from yeastQ29617781
Activities at the Universal Protein Resource (UniProt)Q29617787
Protein degradation and protection against misfolded or damaged proteinsQ29618400
Unraveling the mechanisms involved in motor neuron degeneration in ALSQ29619073
Intermolecular transmission of superoxide dismutase 1 misfolding in living cellsQ30155471
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.Q33689637
A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequenceQ33919640
Signals for COPII-dependent export from the ER: what's the ticket out?Q35147357
Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretionQ35621009
Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretionQ36506015
Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease.Q36862693
Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosisQ36890607
ESCRT-III drives the final stages of CUPS maturation for unconventional protein secretion.Q36905226
Extracellular mutant SOD1 induces microglial-mediated motoneuron injuryQ37442209
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanismsQ37628107
Diversity in unconventional protein secretionQ38078812
The changing scene of amyotrophic lateral sclerosisQ38086771
Unconventional protein secretion: an evolving mechanismQ38105910
New links between SOD1 and metabolic dysfunction from a yeast model of amyotrophic lateral sclerosisQ39363902
Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosisQ40066703
CuZn-superoxide dismutase in human thymus: immunocytochemical localisation and secretion in thymus-derived epithelial and fibroblast cell linesQ40709559
Remodeling of secretory compartments creates CUPS during nutrient starvationQ41883607
The Golgi-associated protein GRASP is required for unconventional protein secretion during development.Q46828620
Secretion and increase of intracellular CuZn superoxide dismutase content in human neuroblastoma SK-N-BE cells subjected to oxidative stressQ48478877
Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.Q54089001
Evidence for secretion of cytosolic CuZn superoxide dismutase by Hep G2 cells and human fibroblastsQ71169525
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectamyotrophic lateral sclerosisQ206901
P304page(s)2691-2700
P577publication date2017-08-09
P1433published inJournal of Cell BiologyQ1524550
P1476titleA diacidic motif determines unconventional secretion of wild-type and ALS-linked mutant SOD1.
P478volume216

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cites work (P2860)
Q64273759A Potential Lock-Type Mechanism for Unconventional Secretion in Fungi
Q98564428Does wild-type Cu/Zn-superoxide dismutase have pathogenic roles in amyotrophic lateral sclerosis?
Q58779209Evaluation of Unconventional Protein Secretion by Saccharomyces cerevisiae and other Fungi
Q64923502Exploring the context of diacidic motif DE as a signal for unconventional protein secretion in eukaryotic proteins.
Q55515366Unconventional Secretion and Intercellular Transfer of Mutant Huntingtin.
Q46207582Unconventional secretion of FABP4 by endosomes and secretory lysosomes.

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