A revised model for the oligomeric state of the N-ethylmaleimide-sensitive fusion protein, NSF.

scientific article published in June 1998

A revised model for the oligomeric state of the N-ethylmaleimide-sensitive fusion protein, NSF. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.273.25.15675
P698PubMed publication ID9624162
P5875ResearchGate publication ID13660681

P50authorAxel T. BrungerQ4830364
P2093author name stringEngel A
Wolpensinger B
Engelhardt H
Müller SA
Hanson PI
Yu RC
Söllner TH
Hohl TM
Fleming KG
P2860cites workN-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusionQ24673247
The ATPase activity of purified CDC48p from Saccharomyces cerevisiae shows complex dependence on ATP-, ADP-, and NADH-concentrations and is completely inhibited by NEM.Q27931559
SNAP receptors implicated in vesicle targeting and fusionQ28131653
Mechanisms of intracellular protein transportQ28131681
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusionQ28255534
The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxinQ28294139
Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasomeQ28294237
Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopyQ28581498
Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuolesQ28609819
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesiclesQ29620271
Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniquesQ30447247
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transportQ33658648
Molecular weight determination by scanning transmission electron microscopyQ36662938
Defining the structure and stability of macromolecular assemblies in solution: the re-emergence of analytical ultracentrifugation as a practical toolQ41063562
Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions.Q41115325
Sequence analysis of the AAA protein familyQ41615832
HYDRO: a computer program for the prediction of hydrodynamic properties of macromoleculesQ43005390
Homotypic vacuolar fusion mediated by t- and v-SNAREsQ48049888
Cloning, sequencing and expression of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum.Q48052667
Boundary analysis in sedimentation velocity experiments.Q52386125
Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profileQ52420901
Correspondence analysis of aligned images of biological particles.Q52714012
N-Ethylmaleimide-sensitive Fusion Protein Contains High and Low Affinity ATP-binding Sites That Are Functionally DistinctQ58413629
Each Domain of theN-Ethylmaleimide-sensitive Fusion Protein Contributes to Its Transport ActivityQ58413637
SNAPs and NSF: general members of the fusion apparatus.Q58413646
Ubiquitous soluble Mg2+-ATPase complexQ58438730
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeastQ59072875
P433issue25
P407language of work or nameEnglishQ1860
P304page(s)15675-15681
P577publication date1998-06-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleA revised model for the oligomeric state of the N-ethylmaleimide-sensitive fusion protein, NSF.
P478volume273

Reverse relations

cites work (P2860)
Q41868502A conserved membrane attachment site in alpha-SNAP facilitates N-ethylmaleimide-sensitive factor (NSF)-driven SNARE complex disassembly.
Q38481396A screen for dominant negative mutants of SEC18 reveals a role for the AAA protein consensus sequence in ATP hydrolysis
Q41727106ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4.
Q50336121An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fusion
Q41918350Analytical ultracentrifugation as a contemporary biomolecular research tool.
Q33231434Annular arrangement and collaborative actions of four domains of protein-disulfide isomerase: a small angle X-ray scattering study in solution
Q33869794Arrangement of subunits in 20 S particles consisting of NSF, SNAPs, and SNARE complexes.
Q41220996Comparative Analysis of the Structure and Function of AAA+ Motors ClpA, ClpB, and Hsp104: Common Threads and Disparate Functions
Q27325771Cryo-EM structure of SNAP-SNARE assembly in 20S particle.
Q27620819Crystal structure of the Sec18p N-terminal domain
Q27765268Crystal structure of the hexamerization domain of N-ethylmaleimide-sensitive fusion protein
Q28565327Disassembly of all SNARE complexes by N-ethylmaleimide-sensitive factor (NSF) is initiated by a conserved 1:1 interaction between α-soluble NSF attachment protein (SNAP) and SNARE complex
Q54501946Dissecting the role of a conserved motif (the second region of homology) in the AAA family of ATPases. Site-directed mutagenesis of the ATP-dependent protease FtsH.
Q24569547Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution
Q58616827Expression of novel proteins by polyomaviruses and recent advances in the structural and functional features of agnoprotein of JC virus, BK virus, and simian virus 40
Q44702192Expression of transcripts encoding AMPA receptor subunits and associated postsynaptic proteins in the macaque brain
Q50119364FliH, a soluble component of the type III flagellar export apparatus of Salmonella, forms a complex with FliI and inhibits its ATPase activity
Q30849052Functional and molecular identification of novel members of the ubiquitous membrane fusion proteins alpha- and gamma-SNAP (soluble N-ethylmaleimide-sensitive factor-attachment proteins) families in Dictyostelium discoideum
Q43755716Genetic interaction between shibire and comatose mutations in Drosophila suggest a role for snap-receptor complex assembly and disassembly for maintenance of synaptic vesicle cycling
Q24633687Hexahistidine-tag-specific optical probes for analyses of proteins and their interactions
Q28140914Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation
Q28567266Identification of Rab6 as an N-ethylmaleimide-sensitive fusion protein-binding protein
Q40780580Inhibition of the membrane fusion machinery prevents exit from the TGN and proteolytic processing by furin
Q29614426Membrane fusion and exocytosis
Q43632102Molecular mass, stoichiometry, and assembly of 20 S particles
Q34250652N-ethylmaleimide sensitive factor (NSF) structure and function.
Q33617477N-ethylmaleimide-sensitive factor interacts with the serotonin transporter and modulates its trafficking: implications for pathophysiology in autism
Q28507124NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex
Q27619352NSF N-terminal domain crystal structure: models of NSF function
Q42375745NSF binds calcium to regulate its interaction with AMPA receptor subunit GluR2
Q34412296Nuclear magnetic resonance structure revealed that the human polyomavirus JC virus agnoprotein contains an α-helix encompassing the Leu/Ile/Phe-rich domain
Q41817833Oligomerization and activation of the FliI ATPase central to bacterial flagellum assembly.
Q28295904Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis
Q46461062Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity.
Q37892093Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF).
Q38803266Review: Progresses in understanding N-ethylmaleimide sensitive factor (NSF) mediated disassembly of SNARE complexes
Q33764725SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18.
Q36327510SNAREpins are functionally resistant to disruption by NSF and alphaSNAP.
Q28204008Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport
Q27932034Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization.
Q88645890Structural basis for disassembly of katanin heterododecamers
Q41791766Structural characterization of full-length NSF and 20S particles
Q33941591Structural insights into the molecular mechanism of Ca(2+)-dependent exocytosis
Q33942089Structural insights into the molecular mechanism of calcium-dependent vesicle-membrane fusion
Q77838121Structure of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum as studied by electron tomography
Q27629334Structure of the AAA ATPase p97
Q27765278Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP
Q28279060The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs
Q35859442The Neurexin/N-Ethylmaleimide-sensitive Factor (NSF) Interaction Regulates Short Term Synaptic Depression
Q34718568The role of the N-D1 linker of the N-ethylmaleimide-sensitive factor in the SNARE disassembly
Q35002875Three αSNAP and 10 ATP molecules are used in SNARE complex disassembly by N-ethylmaleimide-sensitive factor (NSF)

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