In silico characterization of atypical kinase PFD0975w from Plasmodium kinome: a suitable target for drug discovery

scientific article published in February 2012

In silico characterization of atypical kinase PFD0975w from Plasmodium kinome: a suitable target for drug discovery is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1747-0285.2012.01321.X
P698PubMed publication ID22233458

P2093author name stringVishal Trivedi
Swagata Nag
P2860cites workThe transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparumQ21128645
The protein kinase complement of the human genomeQ24324497
The global distribution of clinical episodes of Plasmodium falciparum malariaQ24599466
Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryoteQ24792290
Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarrayQ24804829
PatchDock and SymmDock: servers for rigid and symmetric dockingQ24813335
Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patchQ27643166
Clustal W and Clustal X version 2.0Q27860517
SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modelingQ27860614
Main-chain bond lengths and bond angles in protein structuresQ27860635
Processing of 20S pre-rRNA to 18S ribosomal RNA in yeast requires Rrp10p, an essential non-ribosomal cytoplasmic proteinQ27931072
Yeast Rio1p is the founding member of a novel subfamily of protein serine kinases involved in the control of cell cycle progressionQ27932332
Stereochemistry of polypeptide chain configurationsQ28190300
Evolution of protein kinase signaling from yeast to manQ28205635
Verification of protein structures: patterns of nonbonded atomic interactionsQ29615613
Protein kinases as targets for anti-parasitic chemotherapyQ30828981
Purification and biochemical characterization of a heme containing peroxidase from the human parasite P. falciparumQ30848976
Crystal structure of A. fulgidus Rio2 defines a new family of serine protein kinasesQ30955879
Protein-protein interactions within late pre-40S ribosomes.Q33809292
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathwayQ34139669
The thioredoxin system—From science to clinicQ34274107
Discovery of a novel binding trench in HIV integrase.Q34546744
Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactionsQ35704960
Free heme toxicity and its detoxification systems in humanQ36139710
The RIO kinases: an atypical protein kinase family required for ribosome biogenesis and cell cycle progressionQ36267181
Antimalarial drug discovery: targeting protein kinasesQ36734919
Atypical (RIO) protein kinases from Haemonchus contortus--promise as new targets for nematocidal drugsQ37832015
Regulation of intracellular glutathione levels in erythrocytes infected with chloroquine-sensitive and chloroquine-resistant Plasmodium falciparumQ39241717
Plasmodium berghei: analysis of the gamma-glutamylcysteine synthetase gene in drug-resistant linesQ41916321
Methylene blue reverses endotoxin-induced hypotensionQ43869067
The new permeability pathways induced by the malaria parasite in the membrane of the infected erythrocyte: comparison of results using different experimental techniquesQ44795707
Clotrimazole inhibits hemoperoxidase of Plasmodium falciparum and induces oxidative stress. Proposed antimalarial mechanism of clotrimazoleQ46465773
Autophosphorylation of Archaeoglobus fulgidus Rio2 and crystal structures of its nucleotide-metal ion complexesQ46534829
Structure and activity of the atypical serine kinase Rio1.Q46594066
A family portrait of the RIO kinasesQ46720404
Melatonin inhibits free radical-mediated mitochondrial-dependent hepatocyte apoptosis and liver damage induced during malarial infectionQ46970991
FireDock: fast interaction refinement in molecular dockingQ47598103
Q-SiteFinder: an energy-based method for the prediction of protein-ligand binding sitesQ48498889
Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinaseQ55966866
New perch for the winged helixQ58375376
P433issue4
P921main subjectin silicoQ192572
drug discoveryQ1418791
kinomeQ3197188
serine/threonine protein kinase RIO2Q56560255
serine/threonine protein kinase RIO2, putativeQ56711229
serine/threonine protein kinase RIO2, putativeQ59910081
serine/threonine protein kinase RIO2, putativeQ59956722
serine/threonine protein kinase RIO2, putativeQ59956821
serine/threonine protein kinase RIO2, putativeQ59978455
P304page(s)600-609
P577publication date2012-02-01
P1433published inChemical Biology and Drug DesignQ15749458
P1476titleIn silico characterization of atypical kinase PFD0975w from Plasmodium kinome: a suitable target for drug discovery
P478volume79

Reverse relations

described by source (P1343)
Q56560255serine/threonine protein kinase RIO2
Q56711229serine/threonine protein kinase RIO2, putative
Q59910081serine/threonine protein kinase RIO2, putative
Q59956722serine/threonine protein kinase RIO2, putative
Q59956821serine/threonine protein kinase RIO2, putative
Q59978455serine/threonine protein kinase RIO2, putative

cites work (P2860)
Q27974727In silico characterization of an atypical MAPK phosphatase of Plasmodium falciparum as a suitable target for drug discovery
Q41459443Structural and developmental expression of Ss-riok-2, an RIO protein kinase encoding gene of Strongyloides stercoralis.
Q46242772The RIO protein kinase-encoding gene Sj-riok-2 is involved in key reproductive processes in Schistosoma japonicum

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