Bone marrow endothelial cells increase the invasiveness of human multiple myeloma cells through upregulation of MMP-9: evidence for a role of hepatocyte growth factor

scientific article published in May 2004

Bone marrow endothelial cells increase the invasiveness of human multiple myeloma cells through upregulation of MMP-9: evidence for a role of hepatocyte growth factor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.LEU.2403331
P698PubMed publication ID14999296
P5875ResearchGate publication ID8679970

P2093author name stringAsosingh K
Van Camp B
Van Riet I
Vande Broek I
Vanderkerken K
Leleu X
Facon T
Allegaert V
P2860cites workIdentification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
Laminin-1-induced migration of multiple myeloma cells involves the high-affinity 67 kD laminin receptorQ24642958
Structure and function of hepatocyte growth factorQ28274665
Basement membrane complexes with biological activityQ28285072
Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagenQ28286714
Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membraneQ28292489
Lymphocyte homing and homeostasisQ29619924
Regulation of matrix metalloproteinase expression in tumor invasion.Q33605726
Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancerQ33607176
A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survivalQ33957196
Localization of type IV collagen, laminin, heparan sulfate proteoglycan, and fibronectin to the basal lamina of basement membranesQ36206940
Selective initial in vivo homing pattern of 5T2 multiple myeloma cells in the C57BL/KalwRij mouseQ38274283
Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3.Q38308218
Proteolytic remodeling of extracellular matrixQ40952583
Emerging multipotent aspects of hepatocyte growth factorQ41066829
Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasisQ41121047
Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell linesQ41159708
Overexpression of the met/HGF receptor in renal cell carcinomasQ41190769
Matrix metalloproteinases and the development of cancerQ41239245
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growthQ41596252
Purification and characterization of matrix metalloproteinase 9 from U937 monocytic leukaemia and HT1080 fibrosarcoma cellsQ41908223
Hepatocyte growth factor/scatter factor enhances the invasion of mesothelioma cell lines and the expression of matrix metalloproteinasesQ41972231
Involvement of matrix metalloproteinase type-3 in hepatocyte growth factor-induced invasion of human hepatocellular carcinoma cellsQ43844074
Mechanisms involved in the differential bone marrow homing of CD45 subsets in 5T murine models of myeloma.Q44259834
The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.Q47982958
Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized ratsQ60034429
Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substratesQ70645807
Expression of hepatocyte growth factor and its receptor, the c-met proto-oncogene, in hepatocellular carcinomaQ73107825
Serum levels of the angiogenic cytokines basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in multiple myelomaQ73418817
Hepatocyte growth factor induces colonic cancer cell invasiveness via enhanced motility and protease overproduction. Evidence for PI3 kinase and PKC involvementQ74026103
Invasiveness of hepatocellular carcinoma cell lines: contribution of hepatocyte growth factor, c-met, and transcription factor Ets-1Q74438273
Upregulation of matrix metalloproteinase-9 in murine 5T33 multiple myeloma cells by interaction with bone marrow endothelial cellsQ74802770
A novel host/tumor cell interaction activates matrix metalloproteinase 1 and mediates invasion through type I collagenQ78177336
P433issue5
P921main subjectendotheliumQ111140
neoplastic invasivenessQ112498967
P304page(s)976-982
P577publication date2004-05-01
P1433published inLeukemiaQ6534498
P1476titleBone marrow endothelial cells increase the invasiveness of human multiple myeloma cells through upregulation of MMP-9: evidence for a role of hepatocyte growth factor
P478volume18

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cites work (P2860)
Q38736038Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone.
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Q34155848Bone marrow microenvironment in myelomagenesis: its potential role in early diagnosis
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Q46698294Combining prenylation inhibitors causes synergistic cytotoxicity, apoptosis and disruption of RAS-to-MAP kinase signalling in multiple myeloma cells
Q52535430Endothelial progenitor cells in multiple myeloma neovascularization: a brick to the wall
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Q36977712Extravasation and homing mechanisms in multiple myeloma
Q36973696Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma
Q40258611Hepatitis C Virus E1 protein promotes cell migration and invasion by modulating cellular metastasis suppressor Nm23-H1.
Q36414523Importance of the bone marrow microenvironment in inducing the angiogenic response in multiple myeloma
Q36794225Involvement of the arachidonic acid cytochrome P450 epoxygenase pathway in the proliferation and invasion of human multiple myeloma cells
Q24570128Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
Q53285654Liver‐specific overexpression of matrix metalloproteinase 9 (MMP‐9) in transgenic mice accelerates development of hepatocellular carcinoma
Q36453354Microarray-based understanding of normal and malignant plasma cells
Q35103092Multifunctional role of matrix metalloproteinases in multiple myeloma: a study in the 5T2MM mouse model
Q33820258Neutrophil Gelatinase-Associated Lipocalin (NGAL), Pro-Matrix Metalloproteinase-9 (pro-MMP-9) and Their Complex Pro-MMP-9/NGAL in Leukaemias.
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Q40397931Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model
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Q40330087The involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model
Q132730932The myeloma bone marrow environment and survival signaling
Q37718435Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model
Q42255958Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells
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Q47733010VEGF, ANGPT1, ANGPT2, and MMP-9 expression in the autologous hematopoietic stem cell transplantation and its impact on the time to engraftment.
Q34306330Variation in innate immunity genes and risk of multiple myeloma

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