Requirements for the adaptor protein role of dihydrolipoyl acetyltransferase in the up-regulated function of the pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase

scientific article published in June 1998

Requirements for the adaptor protein role of dihydrolipoyl acetyltransferase in the up-regulated function of the pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.273.23.14130
P698PubMed publication ID9603912
P5875ResearchGate publication ID13680129

P2093author name stringYang D
Gong X
Roche TE
Yakhnin A
P2860cites workCloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in humanQ24321423
Assembly and full functionality of recombinantly expressed dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complexQ24322055
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Domains, motifs, and linkers in 2-oxo acid dehydrogenase multienzyme complexes: a paradigm in the design of a multifunctional proteinQ28297202
Mutagenesis studies of the phosphorylation sites of recombinant human pyruvate dehydrogenase. Site-specific regulationQ28303294
α-Keto acid dehydrogenase complexesQ29037192
Sites of phosphorylation on pyruvate dehydrogenase from bovine kidney and heartQ34269491
Recombinant expression and evaluation of the lipoyl domains of the dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complexQ34319191
Ca2+ as a second messenger within mitochondria of the heart and other tissuesQ37918891
Evidence for lipoic acid mediated NADH and acetyl-CoA stimulation of liver and kidney pyruvate dehydrogenase kinaseQ40031032
Purification of porcine liver pyruvate dehydrogenase complex and characterization of its catalytic and regulatory propertiesQ40109954
Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heartQ42159479
Evidence that rat liver pyruvate dehydrogenase kinase activator protein is a pyruvate dehydrogenase kinaseQ42177329
Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphataseQ42918079
Reconstitution of mammalian pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes: analysis of protein X involvement and interaction of homologous and heterologous dihydrolipoamide dehydrogenasesQ42983941
Lipoyl domain-based mechanism for the integrated feedback control of the pyruvate dehydrogenase complex by enhancement of pyruvate dehydrogenase kinase activity.Q54595311
A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gelsQ56879289
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)14130-14137
P577publication date1998-06-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleRequirements for the adaptor protein role of dihydrolipoyl acetyltransferase in the up-regulated function of the pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase
P478volume273

Reverse relations

cites work (P2860)
Q34727603A pH-dependent kinetic model of dihydrolipoamide dehydrogenase from multiple organisms
Q34557385Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase
Q34408068Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms
Q35083660Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1.
Q40654792Expression and assembly of Arabidopsis thaliana pyruvate dehydrogenase in insect cell cytoplasm
Q28180567Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase
Q41859582Global view of cognate kinase activation by the human pyruvate dehydrogenase complex
Q46976100Ligand-induced effects on pyruvate dehydrogenase kinase isoform 2.
Q22253475Marked differences between two isoforms of human pyruvate dehydrogenase kinase
Q56418745Microenvironmental control of glucose metabolism in tumors by regulation of pyruvate dehydrogenase
Q45129246R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase
Q28188766Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs
Q42821704Recognition of the inner lipoyl-bearing domain of dihydrolipoyl transacetylase and of the blood glucose-lowering compound AZD7545 by pyruvate dehydrogenase kinase 2.
Q34747160Regulation of the activity of the pyruvate dehydrogenase complex
Q41910085Role of protein-protein interactions in the regulation of pyruvate dehydrogenase kinase activity
Q24291531Site specificity of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase
Q73731348Specificity determinants for the pyruvate dehydrogenase component reaction mapped with mutated and prosthetic group modified lipoyl domains
Q28576322Starvation and diabetes reduce the amount of pyruvate dehydrogenase phosphatase in rat heart and kidney
Q27650224Structural and Functional Insights into the Molecular Mechanisms Responsible for the Regulation of Pyruvate Dehydrogenase Kinase 2
Q43884352Structural requirements within the lipoyl domain for the Ca2+-dependent binding and activation of pyruvate dehydrogenase phosphatase isoform 1 or its catalytic subunit
Q42028793The carboxy-terminal tail of pyruvate dehydrogenase kinase 2 is required for the kinase activity

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