The regulatory niche of intestinal stem cells.

scientific article published on 8 April 2016

The regulatory niche of intestinal stem cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JP271931
P932PMC publication ID5009778
P698PubMed publication ID27060879

P50authorLinheng LiQ55233055
P2093author name stringXi C He
Badi Sri Sailaja
P2860cites workLgr5 homologues associate with Wnt receptors and mediate R-spondin signallingQ24310750
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive mannerQ24320153
Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host diseaseQ24626202
PTEN-deficient intestinal stem cells initiate intestinal polyposisQ27316304
Identification of stem cells in small intestine and colon by marker gene Lgr5Q28131701
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal nicheQ28239639
Transcription factor achaete scute-like 2 controls intestinal stem cell fateQ28507783
Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsQ28512115
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cellsQ29614268
Paneth cells constitute the niche for Lgr5 stem cells in intestinal cryptsQ29616197
The relationship between the spleen colony-forming cell and the haemopoietic stem cellQ29620090
Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cellsQ33296957
The CSF-1 receptor fashions the intestinal stem cell nicheQ33894993
Coexistence of quiescent and active adult stem cells in mammalsQ33926891
The intestinal stem cell niche: there grows the neighborhoodQ33947648
Dll1+ secretory progenitor cells revert to stem cells upon crypt damageQ37211856
The role of the visceral mesoderm in the development of the gastrointestinal tractQ37419683
Identification of a cKit(+) colonic crypt base secretory cell that supports Lgr5(+) stem cells in miceQ37548319
Wnt secretion from epithelial cells and subepithelial myofibroblasts is not required in the mouse intestinal stem cell niche in vivo.Q37581662
Stem cells and cancer of the stomach and intestineQ37769649
Intestinal stem cells and their defining nicheQ38179660
Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria.Q38507173
Prospective derivation of a living organoid biobank of colorectal cancer patients.Q38877277
Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-MycQ39126564
Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cellsQ40843426
Evidence for a crucial role of paneth cells in mediating the intestinal response to injuryQ42141259
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewalQ42152874
Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locusQ42915923
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signalingQ45065876
Regulatory T cells occupy an isolated niche in the intestine that is antigen independentQ48157029
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal cryptsQ48515456
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice.Q49165929
Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine.Q50614489
Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells.Q50788436
Stem Cells Matter in Response to Fasting.Q51291919
Wnt signaling regulates Snai1 expression and cellular localization in the mouse intestinal epithelial stem cell niche.Q51903099
An enteroendocrine cell-based model for a quiescent intestinal stem cell niche.Q53598178
Stroma provides an intestinal stem cell niche in the absence of epithelial WntsQ57002669
Monocyte-derived dendritic cells activated by bacteria or by bacteria-stimulated epithelial cells are functionally differentQ60648676
Interleukin-1beta and tumor necrosis factor-alpha induce chemokine and matrix metalloproteinase gene expression in human colonic subepithelial myofibroblastsQ77827337
Expression of LGR5, an intestinal stem cell marker, during each stage of colorectal tumorigenesisQ83313920
Modulation of specific intestinal epithelial progenitors by enteric neuronsQ33947818
Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestineQ34081787
Intestinal stem cells protect their genome by selective segregation of template DNA strands.Q34128111
Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cellsQ34155903
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensableQ34217232
Interconversion between intestinal stem cell populations in distinct nichesQ34231718
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populationsQ34242246
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signallingQ34258498
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markersQ34280882
Intestinal Mesenchymal CellsQ34289166
Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.Q34310988
The intestinal crypt, a prototype stem cell compartmentQ34358606
Mitogenic influence of human R-spondin1 on the intestinal epitheliumQ34444196
Bmi1 is expressed in vivo in intestinal stem cellsQ34785173
Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation.Q34860168
Intestinal myofibroblasts: targets for stem cell therapyQ34979983
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.Q35122385
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis.Q35374941
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.Q35655623
Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and IntestineQ35689780
Inflammation, Innate Immunity, and the Intestinal Stromal Cell Niche: Opportunities and ChallengesQ35754092
Single-molecule transcript counting of stem-cell markers in the mouse intestineQ35799683
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cellsQ35845010
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).Q36061304
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.Q36069386
Epidermal growth factor receptor (EGFR) signaling in cancerQ36353031
Dormant Intestinal Stem Cells Are Regulated by PTEN and Nutritional StatusQ36405460
SOX9 maintains reserve stem cells and preserves radioresistance in mouse small intestine.Q36452176
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.Q36528951
Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewalQ36544448
Generation of mTert-GFP mice as a model to identify and study tissue progenitor cellsQ36802442
Current view: intestinal stem cells and signalingQ37104110
Mesenchymal Cells of the Intestinal Lamina PropriaQ37125569
Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay.Q37194611
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)4827-4836
P577publication date2016-07-28
P1433published inJournal of PhysiologyQ7743612
P1476titleThe regulatory niche of intestinal stem cells
P478volume594