Computational Model of Secondary Palate Fusion and Disruption.

scientific article

Computational Model of Secondary Palate Fusion and Disruption. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/ACS.CHEMRESTOX.6B00350
P932PMC publication ID6196717
P698PubMed publication ID28045533

P50authorMaxwell C K LeungQ79440442
Thomas B KnudsenQ89433834
P2093author name stringM Shane Hutson
Nancy C Baker
Richard M Spencer
P2860cites workThe Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4Q24315313
Disruption of epithelial cell-matrix interactions induces apoptosisQ24673611
Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3Q24675331
Collective cell migration in developmentQ26771268
Systems control of BMP morphogen flow in vertebrate embryosQ27013995
A computational model predicting disruption of blood vessel developmentQ27324767
Simulation of biological cell sorting using a two-dimensional extended Potts modelQ27350237
Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathwayQ28239297
TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDDQ28332332
Jag2-Notch1 signaling regulates oral epithelial differentiation and palate developmentQ28512267
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palateQ28587665
Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowthQ28590687
Multi-scale modeling of tissues using CompuCell3DQ29906688
Evidence for a role of vertebrate Disp1 in long-range Shh signalingQ33552343
Glucocorticoid Inhibition of RNA Synthesis Responsible for Cleft Palate in Mice: A ModelQ33705947
FGFs, heparan sulfate and FGFRs: complex interactions essential for developmentQ33828280
Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implicationsQ34070594
Periderm prevents pathological epithelial adhesions during embryogenesis.Q34117498
Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.Q34127484
Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesisQ34443787
Principles of genetic circuit designQ34502550
Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expressionQ34579328
Regulation of TGF beta 3 gene expression in embryonic palatal tissue.Q52213986
Retinoic acid alters EGF receptor expression during palatogenesis.Q52252181
Retinoids and epidermal growth factor alter embryonic mouse palatal epithelial and mesenchymal cell differentiation in organ culture.Q52258642
Negative interplay of retinoic acid and TGF-β signaling mediated by TG-interacting factor to modulate mouse embryonic palate mesenchymal-cell proliferation.Q53676036
Teratogenic effects of anticonvulsants.Q54099327
Cellular alterations and enhanced induction of cleft palate after coadministration of retinoic acid and TCDDQ60352749
Analysis of the Presence of Cell Proliferation-Related Molecules in the Tgf- β 3 Null Mutant Mouse Palate Reveals Misexpression of EGF and Msx-1Q61757494
Effects of methyl mercury on murine fetal amino acid uptake, protein synthesis and palate closureQ67730370
The influence of the epithelium on palate shelf reorientationQ69975410
Effect of epidermal growth factor on secondary palatal epithelium in vitro: tissue isolation and recombination studiesQ72082498
Induction of Cleft Palate in Rabbits by Several GlucocorticoidsQ72263822
Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesisQ74578263
Descriptive epidemiology of oral clefts in a multiethnic population, Hawaii, 1986-2000Q80935509
Expression patterns of Hedgehog signalling pathway members during mouse palate developmentQ81228738
Opinion: Building epithelial architecture: insights from three-dimensional culture modelsQ34718096
A gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate.Q34999620
Ephrin-B reverse signaling controls septation events at the embryonic midline through separate tyrosine phosphorylation-independent signaling avenuesQ35013801
Palate morphogenesis: current understanding and future directionsQ35111595
Palatogenesis: morphogenetic and molecular mechanisms of secondary palate developmentQ35624827
Embryo stability and vulnerability in an always changing worldQ35629412
Molecular Anatomy of Palate DevelopmentQ35689570
Histomorphological study of palatal shelf elevation during murine secondary palate formation.Q35743828
A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate DevelopmentQ35888906
Mechanisms of tissue fusion during development.Q35893613
Teratogenicity of sodium valproateQ36082034
Retinoid and TGF-β families: crosstalk in development, neoplasia, immunity, and tissue repairQ36124246
TGF-beta3-induced palatogenesis requires matrix metalloproteinasesQ36284069
Molecular control of secondary palate developmentQ36581780
Biologic Basis for a Risk Assessment Model for Cleft PalateQ36786828
Analysis of Zfhx1a mutant mice reveals palatal shelf contact-independent medial edge epithelial differentiation during palate fusion.Q36838700
First-trimester maternal alcohol consumption and the risk of infant oral clefts in Norway: a population-based case-control studyQ37305938
Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null miceQ37429788
Systems toxicology: from basic research to risk assessmentQ37661327
The etiology of cleft palate: a 50-year search for mechanistic and molecular understandingQ37770097
Teratogenic effects of lithium and ethanol in the developing fetusQ39289596
Palate developmentQ39577154
Elevated levels of cAMP alters the effect of epidermal growth factor in vitro on programmed cell death in the secondary palatal epitheliumQ40065305
Glucocorticoids decrease the bioavailability of TGF-beta which leads to a reduced TGF-beta signaling in hepatic stellate cellsQ40489851
Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closureQ41663663
TCDD alters medial epithelial cell differentiation during palatogenesisQ42198166
Death is the major fate of medial edge epithelial cells and the cause of basal lamina degradation during palatogenesisQ42453468
Histochemical localization of glycosaminoglycans during morphogenesis of the secondary palate in miceQ42486474
AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGF alpha, TGF beta 1, TGF beta 2, and TGF beta 3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).Q42538816
Ephrin reverse signaling controls palate fusion via a PI3 kinase-dependent mechanismQ42710708
Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryosQ44061010
Is there an optimal stage for the induction of cleft palate in the mouse?Q44235949
Effects of epidermal growth factor receptor deficiency and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fetal development in miceQ44862640
Etiology of retinoic acid-induced cleft palate varies with the embryonic stage.Q45013810
Maternal corticosteroid use and orofacial cleftsQ46366324
Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alphaQ46411683
Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusionQ46627704
Type IV collagens regulate BMP signalling in DrosophilaQ47070333
Analysis of cell migration, transdifferentiation and apoptosis during mouse secondary palate fusion.Q50477014
Computational modeling and simulation of genital tubercle development.Q50512895
P433issue4
P921main subjectcomputational modelQ1122506
P304page(s)965-979
P577publication date2017-01-20
P1433published inChemical Research in ToxicologyQ473530
P1476titleComputational Model of Secondary Palate Fusion and Disruption
P478volume30

Reverse relations

cites work (P2860)
Q525741263S - Systematic, systemic, and systems biology and toxicology
Q89669447Blood-brain barrier development: Systems modeling and predictive toxicology
Q57801257Development of an organotypic stem cell model for the study of human embryonic palatal fusion
Q41229450Engineering human cell spheroids to model embryonic tissue fusion in vitro
Q89752997Potential frameworks to support evaluation of mechanistic data for developmental neurotoxicity outcomes: A symposium report
Q38704159Programming microphysiological systems for children's health protection
Q50421707Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity
Q87770120Rethinking developmental toxicity testing: Evolution or revolution?
Q33577370Systems Toxicology: Real World Applications and Opportunities.
Q91045906Toxicology testing steps towards computers

Search more.