The induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis

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The induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/CEI.13110
P932PMC publication ID5980314
P698PubMed publication ID29393507

P50authorKazuhisa OuharaQ92772150
Mikihito KajiyaQ47404842
P2093author name stringS Matsuda
K Takeda
T Fujita
Y Sato
N Mizuno
H Kurihara
S Yamasaki
Y Hamamoto
T Iwata
E Sugiyama
K Akutagawa
S Munenaga
P2860cites workTristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNAQ24336740
Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host responseQ28658053
Poly(A)-binding protein-interacting protein 2, a strong regulator of vascular endothelial growth factor mRNA.Q31070579
Neodymium-doped yttrium-aluminium-garnet laser irradiation abolishes the increase in interleukin-6 levels caused by peptidoglycan through the p38 mitogen-activated protein kinase pathway in human pulp cellsQ33413314
Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosisQ33807749
Outer membrane protein 100, a versatile virulence factor of Actinobacillus actinomycetemcomitansQ79300642
Cross-reactive adaptive immune response to oral commensal bacteria results in an induction of receptor activator of nuclear factor-kappaB ligand (RANKL)-dependent periodontal bone resorption in a mouse modelQ80291446
The role of human antigen R, an RNA-binding protein, in mediating the stabilization of toll-like receptor 4 mRNA induced by endotoxin: a novel mechanism involved in vascular inflammationQ80312694
Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, {beta}-defensins and LL37, produced by human epithelial cellsQ95798490
A balancing act: RNA binding protein HuR/TTP axis in endometriosis patientsQ33919012
Myocardial knockdown of mRNA-stabilizing protein HuR attenuates post-MI inflammatory response and left ventricular dysfunction in IL-10-null mice.Q33919479
Suppression of cellular transformation by poly (A) binding protein interacting protein 2 (Paip2).Q34034773
Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistanceQ34854858
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.Q35829153
HuR function in disease.Q35966719
RNA-stabilizing proteins as molecular targets in cardiovascular pathologies.Q35984488
Immune response: the key to bone resorption in periodontal diseaseQ36309235
The role of cytokine mRNA stability in the pathogenesis of autoimmune diseaseQ36510605
Central dogma at the single-molecule level in living cellsQ36692659
The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammationQ37228840
Cytokines that promote periodontal tissue destructionQ37232626
Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitisQ37317152
Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.Q37452251
Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA.Q37459412
Effects of the dietary flavonoid quercetin upon performance and healthQ37544051
Post-transcriptional coordination of immunological responses by RNA-binding proteins.Q38212815
Interleukin-6 as a therapeutic targetQ38318758
Actinobacillus actinomycetemcomitans outer membrane protein 100 triggers innate immunity and production of beta-defensin and the 18-kilodalton cationic antimicrobial protein through the fibronectin-integrin pathway in human gingival epithelial cellsQ38482543
MicroRNA-126 Regulates Inflammatory Cytokine Secretion in Human Gingival Fibroblasts Under High Glucose Via Targeting Tumor Necrosis Factor Receptor Associated Factor 6.Q38734421
Irsogladine maleate inhibits Porphyromonas gingivalis-mediated expression of toll-like receptor 2 and interleukin-8 in human gingival epithelial cells.Q38954282
miR-584 expressed in human gingival epithelial cells is induced by Porphyromonas gingivalis stimulation and regulates interleukin-8 production via lactoferrin receptorQ39063258
HuR post-transcriptionally regulates TNF-α-induced IL-6 expression in human pulmonary microvascular endothelial cells mainly via tristetraprolinQ39378094
Competitive binding of AUF1 and TIAR to MYC mRNA controls its translationQ40135864
Human gingival epithelial cells produce chemotactic factors interleukin-8 and monocyte chemoattractant protein-1 after stimulation with Porphyromonas gingivalis via toll-like receptor 2.Q40565984
Porphyromonas gingivalis infection exacerbates the onset of rheumatoid arthritis in SKG mice.Q40597488
Peroxisome proliferator-activated receptor γ (PPARγ) mediates the protective effect of quercetin against myocardial ischemia-reperfusion injury via suppressing the NF-κB pathwayQ40633496
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferationQ40749123
HuR Enhances Early Restitution of the Intestinal Epithelium by Increasing Cdc42 TranslationQ41728378
Interplay between RNA-binding protein HuR and microRNA-125b regulates p53 mRNA translation in response to genotoxic stressQ41827348
Correction: Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndromeQ42363331
Correction: Discriminating between HuR and TTP binding sites using the k-spectrum kernel methodQ42363659
The regulation of glucose transporter (GLUT1) expression by the RNA binding protein HuR.Q42802986
Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter actinomycetemcomitans.Q43185607
Decreased expression of E-cadherin by Porphyromonas gingivalis-lipopolysaccharide attenuates epithelial barrier functionQ46573607
A novel gingival overgrowth mouse model induced by the combination of CsA and ligature-induced inflammation.Q50854587
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.Q52894285
Secretion of IL-1 beta, TNF-alpha, IL-8 and IL-1ra by human polymorphonuclear leukocytes in response to lipopolysaccharides from periodontopathic bacteria.Q54568340
Implications of periodontal microbiology for the treatment of periodontal infectionsQ72079041
P433issue3
P921main subjectperiodontitisQ520127
RNA-binding proteinsQ3928341
P304page(s)325-336
P577publication date2018-02-02
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleThe induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis
P478volume192

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