Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues

scientific article published in September 1999

Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/12207
P698PubMed publication ID10461223
P5875ResearchGate publication ID12839162

P50authorBernhard LuscherQ41729308
Jean-Marc FritschyQ56978414
P2093author name stringFritschy JM
Benke D
Mohler H
Laurent JP
Belzung C
Crestani F
Baer K
Essrich C
Lorez M
P2860cites workBenzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptorsQ28367959
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioningQ29616330
The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypesQ34481002
Ethoexperimental approaches to the biology of emotionQ39466488
GABAA receptor channelsQ40389943
Emotion: systems, cells, synaptic plasticityQ41000800
Cognitive dysfunction resulting from hippocampal hyperactivity--a possible cause of anxiety disorder?Q41454704
Normal development and behaviour of mice lacking the neuronal cell-surface PrP proteinQ43522858
Contribution of human hippocampal region to novelty detection.Q45976705
Hippocampectomy impairs the memory of recently, but not remotely, acquired trace eyeblink conditioned responsesQ46100838
Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET studyQ47675005
Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT. A preliminary reportQ48224486
Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrinQ48240102
Relationships between trait and state anxiety and the central benzodiazepine receptor: a PET studyQ48248166
Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysisQ48585862
A focal brain abnormality in panic disorder, a severe form of anxietyQ48633253
Link between emotional memory and anxiety states: A study by principal component analysisQ48802566
The behavioral salience of tones as indicated by prepulse inhibition of the startle response: relationship to hearing loss and central neural plasticity in C57BL/6J miceQ48916579
PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning.Q51138420
Differential effect of benzodiazepine sedation in high and low anxious patients in a "real life" stress setting.Q51217659
Effects of ibotenic lesions of mammillary bodies on spontaneous and rewarded spatial alternation in mice.Q52108635
Hippocampal long-term potentiation and neural cell adhesion molecules L1 and NCAMQ59098946
Behavioural Validation of a Light/Dark Choice Procedure for Testing Anti-Anxiety AgentsQ63951857
Reduced benzodiazepine receptor binding in panic disorders measured by iomazenil SPECTQ71368033
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectanxietyQ154430
biasQ742736
P304page(s)833-839
P577publication date1999-09-01
P1433published inNature NeuroscienceQ1535359
P1476titleDecreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues
P478volume2

Reverse relations

cites work (P2860)
Q2829756950 years of hurdles and hope in anxiolytic drug discovery
Q30538580A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation
Q39444689A deficit of brain dystrophin impairs specific amygdala GABAergic transmission and enhances defensive behaviour in mice
Q51439231A gene promotes anxiety in mice-and also in scientists.
Q51886373A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei.
Q34464870A novel GABRG2 mutation, p.R136*, in a family with GEFS+ and extended phenotypes.
Q64084403Ablation of glucocorticoid receptor in the hindbrain of the mouse provides a novel model to investigate stress disorders
Q44678361Abnormal anxiety-related behavior in serotonin transporter null mutant mice: the influence of genetic background
Q48243676Absence of anxiolytic response to chlordiazepoxide in two common background strains exposed to the elevated plus-maze: importance and implications of behavioural baseline
Q28588180Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear
Q42641765Activin tunes GABAergic neurotransmission and modulates anxiety-like behavior.
Q48718504Adult hippocampal neurogenesis is involved in anxiety-related behaviors
Q36411530Alcohol, GABA receptors, and neurodevelopmental disorders
Q43563922Alterations in dystrophin and utrophin expression parallel the reorganization of GABAergic synapses in a mouse model of temporal lobe epilepsy.
Q34976116Altered GABA transmission in a mouse model of increased trait anxiety
Q42263969Altered GABAA receptor expression in brainstem nuclei and SUDEP in Gabrg2(+/Q390X) mice associated with epileptic encephalopathy
Q57173780An Emerging Circuit Pharmacology of GABA Receptors
Q42377342An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors.
Q30538152An anxiety-like phenotype in mice selectively bred for aggression
Q42683643An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits
Q36025710Angiotensin II AT1 receptor blocker candesartan prevents the fast up-regulation of cerebrocortical benzodiazepine-1 receptors induced by acute inflammatory and restraint stress
Q47915510Anti-anhedonic effect of selective serotonin reuptake inhibitors with affinity for sigma-1 receptors in picrotoxin-treated mice.
Q35924378Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABA(A) receptor subtypes
Q30502573Anxiety from a phylogenetic perspective: is there a qualitative difference between human and animal anxiety?
Q51074707Anxiety in healthy humans is associated with orbital frontal chemistry.
Q48128422Anxiety: at the intersection of genes and experience.
Q47980674Anxiolytic-like effects of α-asarone in a mouse model of chronic pain
Q37440206Association study between GABA receptor genes and anxiety spectrum disorders
Q48304837Association study of GABRG2 polymorphisms with suicidal behaviour in schizophrenia patients with alcohol use disorder
Q36562979Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.
Q42644507Behavioral profile of wild mice in the elevated plus-maze test for anxiety
Q35187183Behavioral profiles of inbred strains on novel olfactory, spatial and emotional tests for reference memory in mice
Q42634214Behavioural analysis of four mouse strains in an anxiety test battery
Q45079493Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model.
Q30451624Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice
Q30466591Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes
Q41729281Bidirectional Homeostatic Regulation of a Depression-Related Brain State by Gamma-Aminobutyric Acidergic Deficits and Ketamine Treatment
Q36994585Borna disease virus P protein affects neural transmission through interactions with gamma-aminobutyric acid receptor-associated protein
Q38183555Borna disease virus infection in cats.
Q91641482Brexanolone, a neurosteroid antidepressant, vindicates the GABAergic deficit hypothesis of depression and may foster resilience
Q39990495Calcium-modulating cyclophilin ligand regulates membrane trafficking of postsynaptic GABA(A) receptors.
Q35115978Central GABAergic systems and depressive illness
Q43919465Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats
Q49109928Chemical mapping of anxiety in the brain of healthy humans: an in vivo 1H-MRS study on the effects of sex, age, and brain region
Q34435101Combining genetic and genomic approaches to study mood disorders
Q27305122Complex control of GABA(A) receptor subunit mRNA expression: variation, covariation, and genetic regulation
Q35690731Concussive brain injury enhances fear learning and excitatory processes in the amygdala
Q48615603Contrasting phenotypes of C57BL/6JOlaHsd, 129S2/SvHsd and 129/SvEv mice in two exploration-based tests of anxiety-related behaviour
Q47349501Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice
Q64102147Cortical GABAergic Dysfunction in Stress and Depression: New Insights for Therapeutic Interventions
Q26750907Cortical and subcortical gamma amino acid butyric acid deficits in anxiety and stress disorders: Clinical implications
Q48156052Cortical thinning in obsessive compulsive disorder.
Q44835112Corticotrophin releasing factor-induced synaptic plasticity in the amygdala translates stress into emotional disorders.
Q30490998Critical role of the 65-kDa isoform of glutamic acid decarboxylase in consolidation and generalization of Pavlovian fear memory
Q27637525Crystal structure of the GABAA-receptor-associated protein, GABARAP
Q34249227Current perspectives on the pathophysiology of schizophrenia, depression, and anxiety disorders
Q34798306Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.
Q48129765Defects at the crossroads of GABAergic signaling in generalized genetic epilepsies
Q34615783Defects in dendrite and spine maturation and synaptogenesis associated with an anxious-depressive-like phenotype of GABAA receptor-deficient mice
Q43536237Deficiency of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory.
Q30532216Deficits in trace cued fear conditioning in galanin-treated rats and galanin-overexpressing transgenic mice
Q35881844Diabetes induces GABA receptor plasticity in murine vagal motor neurons
Q35546401Diagnostic Criteria for Psychiatric Disorders for Use with Adults with Learning Disabilities/Mental Retardation(DC‐LD) and the diagnosis of anxiety disorders: a review
Q64084725Diazepam Accelerates GABAR Synaptic Exchange and Alters Intracellular Trafficking
Q34136074Differences between trait fear and trait anxiety: Implications for psychopathology
Q43233240Differential localization of gamma-aminobutyric acid type A and glycine receptor subunits and gephyrin in the human pons, medulla oblongata and uppermost cervical segment of the spinal cord: an immunohistochemical study.
Q39732193Differential molecular and behavioural alterations in mouse models of GABRG2 haploinsufficiency versus dominant negative mutations associated with human epilepsy
Q43648884Differential sensitivity to the anxiolytic effects of ethanol and flunitrazepam in PKCgamma null mutant mice
Q104509542Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice
Q36509663Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin.
Q44971605Does amygdaloid corticotropin-releasing hormone (CRH) mediate anxiety-like behaviors? Dissociation of anxiogenic effects and CRH release
Q37136743Dopamine D4 Receptors Regulate GABAA Receptor Trafficking via an Actin/Cofilin/Myosin-dependent Mechanism.
Q34749269Drug interactions at GABA(A) receptors
Q47744146Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus
Q35115792Early life experience shapes the functional organization of stress-responsive visceral circuits
Q33895482Early-life infection is a vulnerability factor for aging-related glial alterations and cognitive decline
Q37703475Effects of Traumatic Stress Induced in the Juvenile Period on the Expression of Gamma-Aminobutyric Acid Receptor Type A Subunits in Adult Rat Brain
Q46936239Effects of baclofen on anxiety, sexual motivation, and olfactory perception in male mice in different psychoemotional states
Q34097713Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice
Q42145810Emotion and cognition in high and low stress sensitive mouse strains: a combined neuroendocrine and behavioral study in BALB/c and C57BL/6J mice.
Q46894690Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors
Q48560999Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor.
Q35236855Experimental animal models for the simulation of depression and anxiety.
Q42436062Facilitated CA1 hippocampal synaptic plasticity in dystrophin-deficient mice: role for GABAA receptors?
Q45183577Fluoxetine disrupts the integration of anxiety and aversive memories
Q38427758Functional neuroanatomy on the working memory under emotional distraction in patients with generalized anxiety disorder
Q95804738GABA GABA A: modulating sensitivity to drugs and alcohol
Q46914797GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI.
Q30363617GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.
Q34204921GABA(A) receptor subtypes: dissecting their pharmacological functions
Q43540494GABA(A) receptors containing (alpha)5 subunits in the CA1 and CA3 hippocampal fields regulate ethanol-motivated behaviors: an extended ethanol reward circuitry.
Q43968692GABA-ergic modulation of prefrontal spatio-temporal activation pattern during emotional processing: a combined fMRI/MEG study with placebo and lorazepam.
Q64986634GABAA Receptor Density Is Not Altered by a Novel Herbal Anxiolytic Treatment.
Q34569409GABAA receptor drugs and neuronal plasticity in reward and aversion: focus on the ventral tegmental area
Q24801914GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.
Q30421260GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism
Q34979365GABAA receptor trafficking-mediated plasticity of inhibitory synapses
Q41984180GABAA receptor α and γ subunits shape synaptic currents via different mechanisms
Q28241963GABAA receptor-acting neurosteroids: a role in the development and regulation of the stress response
Q36637673GABAA receptors as targets for novel anxiolytic drugs
Q36659853GABAA receptors in central nervous system disease: anxiety, epilepsy, and insomnia
Q34400464GABAA-receptor plasticity during long-term exposure to and withdrawal from progesterone
Q38947394GABAergic Regulation of Adult Hippocampal Neurogenesis
Q36740355GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states
Q34448259GABAergic control of critical developmental periods for anxiety- and depression-related behavior in mice
Q36668325GABAergic control of depression-related brain states
Q28478892GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats
Q42531323GIT1 and βPIX are essential for GABA(A) receptor synaptic stability and inhibitory neurotransmission.
Q48416202Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance
Q34271352Gender-specific contribution of the GABAA subunit genes on 5q33 in methamphetamine use disorder
Q48179004Generalisation of conditioned fear and its behavioural expression in mice.
Q35746041Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression
Q36021405Genetic Deletion of the Clathrin Adaptor GGA3 Reduces Anxiety and Alters GABAergic Transmission
Q35104041Genetic animal models of anxiety
Q34517497Genetic basis of anxiety-like behaviour: a critical review
Q36064163Genetic biomarkers of depression
Q44281916Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction.
Q30478587Genetics of anxiety and trauma-related disorders
Q46798855Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors.
Q30486159Glutamatergic and GABAergic modulations of ultrasonic vocalizations during maternal separation distress in mouse pups
Q24613178Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal
Q40056976Heat induced temperature dysregulation and seizures in Dravet Syndrome/GEFS+ Gabrg2+/Q390X mice
Q42498243Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone.
Q47157251Hippocampal GABA enables inhibitory control over unwanted thoughts.
Q35214789Hippocampal modulation of sensorimotor processes
Q37872468Hippocampal regulation of aversive memories.
Q27437613Human stiff-person syndrome IgG induces anxious behavior in rats
Q34573086Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation.
Q33931028Impaired GABA(A) receptor endocytosis and its correlation to spatial memory deficits
Q36013388Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice
Q34085629Increase in expression of the GABA(A) receptor alpha(4) subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists
Q41586786Increased Motor-Impairing Effects of the Neuroactive Steroid Pregnanolone in Mice with Targeted Inactivation of the GABAA Receptor γ2 Subunit in the Cerebellum.
Q28586201Increased anxiety-like behavior and enhanced synaptic efficacy in the amygdala of GluR5 knockout mice
Q30492433Induction of neuronal vascular endothelial growth factor expression by cAMP in the dentate gyrus of the hippocampus is required for antidepressant-like behaviors
Q29616854Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
Q100723177Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses
Q31900249Input-dependent synaptic targeting of alpha(2)-subunit-containing GABA(A) receptors in synapses of hippocampal pyramidal cells of the rat.
Q41281812Investigation of ethanol-induced impairment of spatial memory in gamma2 heterozygous knockout mice.
Q46796503Investigation of the abundance and subunit composition of GABAA receptor subtypes in the cerebellum of alpha1-subunit-deficient mice.
Q46684358Juvenile stress-induced alteration of maturation of the GABAA receptor alpha subunit in the rat.
Q47965028Learning and memory performance in mice lacking the GAL-R1 subtype of galanin receptor
Q48690295Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus
Q31966789Localization of two major GABA(A) receptor subunits in the dentate gyrus of the rat and cell type-specific up-regulation following entorhinal cortex lesion.
Q43205095Lorazepam modulates orbitofrontal signal changes during emotional processing in catatonia
Q43594220Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice.
Q34789999Making sense of nonsense GABA(A) receptor mutations associated with genetic epilepsies
Q34420641Measuring normal and pathological anxiety-like behaviour in mice: a review.
Q34995058Mechanisms of GABAA receptor assembly and trafficking: implications for the modulation of inhibitory neurotransmission.
Q37856287Medicinal chemistry of ρ GABAC receptors.
Q36624181Meditation and Yoga can Modulate Brain Mechanisms that affect Behavior and Anxiety-A Modern Scientific Perspective
Q28510086Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses
Q38883198Molecular Pathogenic Basis for GABRG2 Mutations Associated With a Spectrum of Epilepsy Syndromes, From Generalized Absence Epilepsy to Dravet Syndrome
Q92010373Molecular basis for and chemogenetic modulation of comorbidities in GABRG2-deficient epilepsies
Q33194775Molecular dissection of the amygdala and its relevance to autism
Q34510367Molecular pathways of anxiety revealed by knockout mice
Q37127405Molecular targets of anxiety: from membrane to nucleus.
Q34574021Mouse anxiety: the power of knockout
Q36841480Multiple molecular mechanisms for a single GABAA mutation in epilepsy
Q33717685Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors
Q39311440Neurobiological mechanisms of stress resilience and implications for the aged population.
Q51071588Neurobiology of anxiety and fear: challenges for genomic science of the new millennium.
Q32064653Neurobiology of generalized anxiety disorder
Q30498893Neurobiology of memory and anxiety: from genes to behavior
Q35971833Neurosteroids and GABA-A Receptor Function
Q52641631Neurosteroids in Schizophrenia: Pathogenic and Therapeutic Implications.
Q36666746Neurosteroids, stress and depression: potential therapeutic opportunities.
Q46704914Neurotensin enhances GABAergic activity in rat hippocampus CA1 region by modulating L-type calcium channels
Q30493888On the importance of inhibition: central and peripheral manifestations of nonlinear inhibitory processes in neural systems
Q48726910Orexins, sleep and arousal
Q47108015Overexpression of transmembrane protein 168 in the mouse nucleus accumbens induces anxiety and sensorimotor gating deficit
Q33506763Parallel changes in gene expression in peripheral blood mononuclear cells and the brain after maternal separation in the mouse
Q38579331Pathophysiological aspects of diversity in neuronal inhibition: a new benzodiazepine pharmacology
Q41159670Pathway analysis of genome-wide association datasets of personality traits
Q48272441Phospholipase C-related inactive protein is involved in trafficking of gamma2 subunit-containing GABA(A) receptors to the cell surface.
Q43757605Post-training excitotoxic lesions of the dorsal hippocampus attenuate forward trace, backward trace, and delay fear conditioning in a temporally specific manner
Q46935379Presynaptic terminals independently regulate synaptic clustering and autophagy of GABAA receptors in Caenorhabditis elegans.
Q47316274Prodepressant- and anxiogenic-like effects of serotonin-selective, but not noradrenaline-selective, antidepressant agents in mice lacking α2-containing GABAA receptors
Q48173710Prodynorphin gene deletion increased anxiety-like behaviours, impaired the anxiolytic effect of bromazepam and altered GABAA receptor subunits gene expression in the amygdala
Q33919784Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats.
Q45743608Progressive postnatal assembly of limbic-autonomic circuits revealed by central transneuronal transport of pseudorabies virus.
Q47820916Protein kinase C is essential for kainate-induced anxiety-related behavior and glutamatergic synapse upregulation in prelimbic cortex.
Q36692356Psychological risk factors in headache
Q35806141Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling.
Q33927727Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury.
Q30486124Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons
Q43757430Region-specific developmental specialization of GABA-glycine cosynapses in laminas I-II of the rat spinal dorsal horn.
Q36866354Regulation of anxiety during the postpartum period
Q27649952Regulation of synaptic inhibition by phospho-dependent binding of the AP2 complex to a YECL motif in the GABAA receptor  2 subunit
Q30474166Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations
Q39182365Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus
Q34583254Role of GABA in anxiety and depression
Q36407601Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights
Q77354257Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone
Q48651137Role of bombesin (BN)-like peptides/receptors in emotional behavior by comparison of three strains of BN-like peptide receptor knockout mice
Q28579679Sex differences in anxiety, sensorimotor gating and expression of the alpha4 subunit of the GABAA receptor in the amygdala after progesterone withdrawal
Q33954793Sex differences in diazepam effects and parvalbumin-positive GABA neurons in trait anxiety Long Evans rats
Q48032618Short- and long-term effects of juvenile stressor exposure on the expression of GABAA receptor subunits in rats
Q52540485Single-channel properties of neuronal GABAA receptors from mice lacking the 2 subunit.
Q42375144Slow degradation and aggregation in vitro of mutant GABAA receptor gamma2(Q351X) subunits associated with epilepsy
Q34634067Stop that! Inhibition, sensitization, and their neurovisceral concomitants
Q34400471Stress and neuroactive steroids
Q34349185Subcellular localization and regulation of GABAA receptors and associated proteins
Q33720433Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrus
Q40237197Synaptic GABAA receptors are directly recruited from their extrasynaptic counterparts
Q51076448Synaptic plasticity in the basolateral amygdala in transgenic mice expressing dominant-negative cAMP response element-binding protein (CREB) in forebrain.
Q44734604TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors
Q46437590Targeted invalidation of CCK2 receptor gene induces anxiolytic-like action in light-dark exploration, but not in fear conditioning test
Q30464954The GABAergic deficit hypothesis of major depressive disorder.
Q40395726The GABRG2 mutation, Q351X, associated with generalized epilepsy with febrile seizures plus, has both loss of function and dominant-negative suppression
Q39593426The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through.
Q38282318The GAD65 knock out mouse - a model for GABAergic processes in fear- and stress-induced psychopathology
Q30462832The age of anxiety: role of animal models of anxiolytic action in drug discovery
Q36247092The ascent of mouse: advances in modelling human depression and anxiety
Q30473428The biology of fear- and anxiety-related behaviors
Q30474232The clinical implications of mouse models of enhanced anxiety.
Q28586332The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning
Q35244210The dynamic modulation of GABA(A) receptor trafficking and its role in regulating the plasticity of inhibitory synapses
Q24672913The gamma-aminobutyric acid type A (GABAA) receptor-associated protein (GABARAP) promotes GABAA receptor clustering and modulates the channel kinetics
Q27312345The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration
Q35977083The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit
Q35202929The neurobiology and control of anxious states
Q36712354The relevance of neuroactive steroids in schizophrenia, depression, and anxiety disorders
Q24630566The role of the GABRA2 polymorphism in multiplex alcohol dependence families with minimal comorbidity: within-family association and linkage analyses
Q34438172The social brain: transcriptome assembly and characterization of the hippocampus from a social subterranean rodent, the colonial tuco-tuco (Ctenomys sociabilis)
Q36613901Tiagabine in anxiety disorders
Q35087068Toward a molecular architecture of personality.
Q84967046Toward an efficient and integrative analysis of limited-choice behavioral experiments
Q34133337Trace fear conditioning in mice.
Q28594296Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors
Q30500598Trace fear conditioning is enhanced in mice lacking the delta subunit of the GABAA receptor
Q39145945Trafficking-deficient mutant GABRG2 subunit amount may modify epilepsy phenotype
Q41856355Type A GABA-receptor-dependent synaptic transmission sculpts dendritic arbor structure in Xenopus tadpoles in vivo.
Q37389012Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition
Q44978629Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.
Q30496339gamma-Aminobutyric acid-type A receptor deficits cause hypothalamic-pituitary-adrenal axis hyperactivity and antidepressant drug sensitivity reminiscent of melancholic forms of depression
Q34295813α2-containing GABA(A) receptors: a target for the development of novel treatment strategies for CNS disorders.
Q47853123α4βδ-GABAA receptors in dorsal hippocampal CA1 of adolescent female rats traffic to the plasma membrane of dendritic spines following voluntary exercise and contribute to protection of animals from activity-based anorexia through localization at exc
Q58712240γ2 GABAR Trafficking and the Consequences of Human Genetic Variation

Search more.