Synuclein aggregation: possible role in traumatic brain injury

scientific article published in November 2003

Synuclein aggregation: possible role in traumatic brain injury is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-4886(03)00401-1
P698PubMed publication ID14637075

P2093author name stringW Dalton Dietrich
Helen M Bramlett
P2860cites workalpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodiesQ24653247
Mutation in the alpha-synuclein gene identified in families with Parkinson's diseaseQ27860459
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Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodiesQ28287237
Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's diseaseQ33732327
beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's diseaseQ33947152
Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry.Q33961445
Age-dependent synuclein pathology following traumatic brain injury in miceQ34278990
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseasesQ34679230
Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanismsQ34977039
The metallobiology of Alzheimer's diseaseQ35104793
Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.Q35156240
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genesQ35754459
The association between head trauma and Alzheimer's diseaseQ38140596
Transgenic mice and knockout mutants in the study of oxidative stress in brain injuryQ40965333
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesionsQ44177978
The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injuryQ44860056
Antibodies to the C-terminus of the beta-amyloid precursor protein (APP): a site specific marker for the detection of traumatic axonal injuryQ44873866
Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid ?-protein and tau proteinQ46140201
Early microvascular and neuronal consequences of traumatic brain injury: a light and electron microscopic study in ratsQ48113684
One-year study of spatial memory performance, brain morphology, and cholinergic markers after moderate controlled cortical impact in ratsQ48250924
Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's diseaseQ48266946
Progressive atrophy and neuron death for one year following brain trauma in the rat.Q48578206
Quantitative structural changes in white and gray matter 1 year following traumatic brain injury in rats.Q48605051
Temporal and regional patterns of axonal damage following traumatic brain injury: a beta-amyloid precursor protein immunocytochemical study in rats.Q48607800
Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat.Q49159063
Ventricular dilation, cortical atrophy, and neuropsychological outcome following traumatic brain injury.Q52055249
Stalning af amyloid percursor protein to study axonal damage in mild head InjuryQ52056275
Head injury as a risk factor for Alzheimer's disease.Q53195647
Alpha-synuclein in familial Alzheimer disease: epitope mapping parallels dementia with Lewy bodies and Parkinson disease.Q53349523
Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's diseaseQ64784256
Alpha-synuclein immunoreactivity is present in axonal swellings in neuroaxonal dystrophy and acute traumatic brain injuryQ64816474
Extensive axonal Lewy neurites in Parkinson's disease: a novel pathological feature revealed by alpha-synuclein immunocytochemistryQ64861825
Diffuse axonal injury in head injury: definition, diagnosis and gradingQ69698410
Risk factors for Parkinson's diseaseQ70514711
Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injuryQ72624827
Chronic histopathological consequences of fluid-percussion brain injury in rats: effects of post-traumatic hypothermiaQ73087357
Documented head injury in early adulthood and risk of Alzheimer's disease and other dementiasQ73172415
Occurrence of human alpha-synuclein immunoreactive neurons with neurofibrillary tangle formation in the limbic areas of patients with Alzheimer's diseaseQ73571882
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectSynucleinQ24767155
P304page(s)27-30
P577publication date2003-11-01
P1433published inExperimental NeurologyQ5421127
P1476titleSynuclein aggregation: possible role in traumatic brain injury
P478volume184

Reverse relations

cites work (P2860)
Q45061432Biomarkers in the clinical diagnosis and management of traumatic brain injury
Q43129915Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction.
Q36366723Long-Term Consequences of Traumatic Brain Injury: Current Status of Potential Mechanisms of Injury and Neurological Outcomes
Q33636374Rationale for therapeutic silencing of alpha-synuclein in Parkinson's disease
Q39257016Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries

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