scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1100592821 |
P356 | DOI | 10.1038/S41598-017-19135-7 |
P8608 | Fatcat ID | release_nd5jno3zkzaqjgcevg45enpmpa |
P932 | PMC publication ID | 5789057 |
P698 | PubMed publication ID | 29379013 |
P50 | author | Nikolai Zvonok | Q83904178 |
Alexandros Makriyannis | Q28480394 | ||
Jeffrey W. Hudgens | Q46112986 | ||
P2093 | author name string | Xiaoyu Ma | |
Sergiy Tyukhtenko | |||
Hongwei Huang | |||
Kiran Vemuri | |||
Spiro Pavlopoulos | |||
Ioannis Karageorgos | |||
Elyssia S Gallagher | |||
Girija Rajarshi | |||
Mahmoud L Nasr | |||
P2860 | cites work | Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. | Q51371435 |
Physics-based enzyme design: predicting binding affinity and catalytic activity | Q56893550 | ||
Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling | Q24324741 | ||
Comparison of simple potential functions for simulating liquid water | Q26778447 | ||
Chemical probes of endocannabinoid metabolism | Q26863202 | ||
Therapeutic potential of monoacylglycerol lipase inhibitors | Q26991513 | ||
Structural basis for human monoglyceride lipase inhibition | Q27658438 | ||
Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution | Q27666922 | ||
The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes | Q27678921 | ||
Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase | Q27679889 | ||
Substrate selectivity of bacterial monoacylglycerol lipase based on crystal structure | Q27690646 | ||
cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases | Q28252158 | ||
Enzymatic pathways that regulate endocannabinoid signaling in the nervous system | Q28390932 | ||
A network representation of protein structures: implications for protein stability. | Q30351373 | ||
2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspective | Q33781776 | ||
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis | Q33914549 | ||
Why are proteins so robust to site mutations? | Q34108965 | ||
HDX workbench: software for the analysis of H/D exchange MS data | Q34301944 | ||
Crystal Structure of the Human Cannabinoid Receptor CB1. | Q34543208 | ||
Inhibition of monoacylglycerol lipase prevents chronic traumatic encephalopathy-like neuropathology in a mouse model of repetitive mild closed head injury. | Q35143497 | ||
Residues crucial for maintaining short paths in network communication mediate signaling in proteins | Q35193500 | ||
Communication routes in ARID domains between distal residues in helix 5 and the DNA-binding loops | Q35238111 | ||
Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice | Q35265686 | ||
The metabolic serine hydrolases and their functions in mammalian physiology and disease | Q35333042 | ||
OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins | Q35846188 | ||
Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action | Q35920709 | ||
Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL). | Q36104505 | ||
Specific Inter-residue Interactions as Determinants of Human Monoacylglycerol Lipase Catalytic Competency: A ROLE FOR GLOBAL CONFORMATIONAL CHANGES. | Q36548313 | ||
Membrane phospholipid bilayer as a determinant of monoacylglycerol lipase kinetic profile and conformational repertoire | Q36949890 | ||
Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice | Q37214542 | ||
Endocannabinoid-mediated control of synaptic transmission | Q37363621 | ||
Active-site inhibitors modulate the dynamic properties of human monoacylglycerol lipase: a hydrogen exchange mass spectrometry study | Q37374110 | ||
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling | Q37416400 | ||
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons | Q37444504 | ||
Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses | Q37617606 | ||
In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects. | Q37637750 | ||
Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis | Q37679402 | ||
A review on the monoacylglycerol lipase: at the interface between fat and endocannabinoid signalling. | Q37758870 | ||
Catalytic contributions from remote regions of enzyme structure | Q37933310 | ||
Functional role of a non-active site residue Trp(23) on the enzyme activity of Escherichia coli thioesterase I/protease I/lysophospholipase L(1). | Q38353030 | ||
From local to global changes in proteins: a network view | Q38384421 | ||
Controlling Allosteric Networks in Proteins | Q38740825 | ||
Using THz Spectroscopy, Evolutionary Network Analysis Methods, and MD Simulation to Map the Evolution of Allosteric Communication Pathways in c-Type Lysozymes | Q40576749 | ||
A comparison of novel, selective fatty acid amide hydrolase (FAAH), monoacyglycerol lipase (MAGL) or dual FAAH/MAGL inhibitors to suppress acute and anticipatory nausea in rat models | Q41155213 | ||
Sequential structural changes of Escherichia coli thioesterase/protease I in the serial formation of Michaelis and tetrahedral complexes with diethyl p-nitrophenyl phosphate. | Q44503660 | ||
Roles of tryptophan residues on the Rhizopus delemar lipase activity: chemical modification in a water-olive oil emulsion | Q47922231 | ||
Conformational transition pathway in the inhibitor binding process of human monoacylglycerol lipase | Q48628554 | ||
Systematic mutation of bacteriophage T4 lysozyme | Q50183536 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1719 | |
P577 | publication date | 2018-01-29 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase | |
P478 | volume | 8 |
Q89597584 | A Thermolabile Phospholipase B from Talaromyces marneffei GD-0079: Biochemical Characterization and Structure Dynamics Study |
Q101051220 | Conformational gating, dynamics and allostery in human monoacylglycerol lipase |
Q64273189 | Structural Perspective on Revealing and Altering Molecular Functions of Genetic Variants Linked with Diseases |
Q64262145 | Structural and free energy landscape of novel mutations in ribosomal protein S1 (rpsA) associated with pyrazinamide resistance |