PET Imaging of Serotonin Transporters With 4-[(18)F]-ADAM in a Parkinsonian Rat Model With Porcine Neural Xenografts

scientific article

PET Imaging of Serotonin Transporters With 4-[(18)F]-ADAM in a Parkinsonian Rat Model With Porcine Neural Xenografts is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3727/096368915X688236
P698PubMed publication ID25994923

P50authorShinn-Chih WuQ44032886
P2093author name stringKuo-Hsing Ma
Wen-Sheng Huang
Cheng-Yi Cheng
Chyng-Yann Shiue
Ta-Kai Chou
Mei-Hsiu Liao
Shao-Ju Weng
Yuahn-Sieh Huang
I-Hsun Li
Chuang-Hsin Chiu
P2860cites workImaging Approaches to Parkinson DiseaseQ22241268
Molecular imaging in neuroscience research with small-animal PET in rodentsQ33795327
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's diseaseQ33951094
Natural antibodies and the host immune responses to xenograftsQ34015343
Neural tissue xenograftingQ34023220
Study on the neuroprotective effect of fluoxetine against MDMA-induced neurotoxicity on the serotonin transporter in rat brain using micro-PET.Q34610812
Brain serotonin transporter binding in non-depressed patients with Parkinson's diseaseQ34619565
Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's diseaseQ35575385
Cell replacement therapy for Parkinson's diseaseQ37325157
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteriaQ37631959
The serotonergic system in Parkinson's diseaseQ37924025
The immunological challenges of cell transplantation for the treatment of Parkinson's disease.Q38004257
Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's diseaseQ39111166
Genetic variation and phylogenetics of Lanyu and exotic pig breeds in Taiwan analyzed by nineteen microsatellite markersQ40058303
Interpopulation and intrapopulation maternal lineage genetics of the Lanyu pig (Sus scrofa) by analysis of mitochondrial cytochrome b and control region sequencesQ40113319
Clinical application of neuronal grafts in Parkinson's diseaseQ40495990
Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesionsQ42170132
Serotonergic neurons mediate dyskinesia side effects in Parkinson's patients with neural transplantsQ42997555
Investigating the effects of noise-induced hearing loss on serotonin transporters in rat brain using 4-[18F]-ADAM/small animal PET.Q43631092
Effects of immunosuppressive treatment on host responses against intracerebral porcine neural tissue xenografts in ratsQ43675887
Porcine neural xenografts in rats and mice: donor tissue development and characteristics of rejection.Q43780616
Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantationQ43870528
Rapid induction of serotonergic hyperinnervation in the adult rat striatum with extensive dopaminergic denervationQ44443013
Positron emission tomography of striatal serotonin transporters in Parkinson diseaseQ44585433
PET imaging of the brain serotonin transporters (SERT) with N,N-dimethyl-2-(2-amino-4-[18F]fluorophenylthio)benzylamine (4-[18F]-ADAM) in humans: a preliminary studyQ44897778
Transgenic-cloned pigs systemically expressing red fluorescent protein, Kusabira-OrangeQ45872690
Dual-isotope single-photon emission computed tomography for dopamine and serotonin transporters in normal and Parkinsonian monkey brains.Q45914303
New MRI, 18F-DOPA and 11C-(+)-alpha-dihydrotetrabenazine templates for Macaca fascicularis neuroimaging: advantages to improve PET quantification.Q46021600
An improved synthesis of 4-[18F]-ADAM, a potent serotonin transporter imaging agentQ46065107
Validation of 4-[18F]-ADAM as a SERT imaging agent using micro-PET and autoradiographyQ46124952
Imaging serotonin transporters using [123I]ADAM SPECT in a parkinsonian primate modelQ46429439
Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain.Q46500530
Pig xenografts to the immunocompetent rat brain: Survival rates using distinct neurotoxic lesions in the nigrostriatal pathway and two rat strainsQ46603117
Olfactory ensheathing glial co-grafts improve functional recovery in rats with 6-OHDA lesionsQ46776002
An automated synthesis of N,N-dimethyl-2-(2-amino-4-[18F]fluorophenylthio)benzylamine (4-[18F]-ADAM) for imaging serotonin transportersQ46786954
Effect of age on markers for monoaminergic neurons of normal and MPTP-lesioned rhesus monkeys: a multi-tracer PET studyQ46868958
Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease.Q48095855
Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissuesQ48160477
PET imaging of serotonin transporters with 4-[18F]-ADAM in a Parkinsonian rat modelQ48307627
Impact of dopamine versus serotonin cell transplantation for the development of graft-induced dyskinesia in a rat Parkinson model.Q48452231
Hyperinnervation of the striatum by dorsal raphe afferents after dopamine-depleting brain lesions in neonatal ratsQ48479000
Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-fluorodopa studies in two patients with putaminal implantsQ48535750
Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neuronsQ48560518
Characterisation of partial volume effect and region-based correction in small animal positron emission tomography (PET) of the rat brain.Q48630420
Effects of 6-hydroxydopamine lesions of the nigrostriatal pathway on striatal serotonin innervation in adult ratsQ48638093
Serotonergic sprouting is induced by dopamine-lesion in substantia nigra of adult rat brainQ48673694
Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesiaQ48880426
Kinetic evaluation of [11C]dihydrotetrabenazine by dynamic PET: measurement of vesicular monoamine transporterQ48882689
Cell fusion phenomena detected after in utero transplantation of Ds-red-harboring porcine amniotic fluid stem cells into EGFP transgenic miceQ50462764
Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study.Q51431445
Midbrain serotonin transporters in de novo and L-DOPA-treated patients with early Parkinson's disease--a [123 I]-ADAM SPECT study.Q52899952
Serotonergic and dopaminergic mechanisms in graft-induced dyskinesia in a rat model of Parkinson's disease.Q53169445
Characterization of 4-[18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: a dynamic study.Q53187794
Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio.Q53223116
P433issue2
P921main subjectParkinson's diseaseQ11085
xenograftQ64148587
P304page(s)301-311
P577publication date2015-05-20
P1433published inCell TransplantationQ15761863
P1476titlePET Imaging of Serotonin Transporters With 4-[(18)F]-ADAM in a Parkinsonian Rat Model With Porcine Neural Xenografts
P478volume25

Reverse relations

Q91989470Bone regeneration in Ds-Red pig calvarial defect using allogenic transplantation of EGFP-pMSCs - A comparison of host cells and seeding cells in the scaffoldcites workP2860