Restricted utilization of germ-line VH3 genes and short diverse third complementarity-determining regions (CDR3) in human fetal B lymphocyte immunoglobulin heavy chain rearrangements

scientific article published on January 1, 1992

Restricted utilization of germ-line VH3 genes and short diverse third complementarity-determining regions (CDR3) in human fetal B lymphocyte immunoglobulin heavy chain rearrangements is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.1830220136
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Feji.1830220136
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.1830220136
P698PubMed publication ID1730252

P2093author name stringVossen JM
Timmers E
Schuurman RK
Kenter MJ
Raaphorst FM
Van Tol MJ
P2860cites workA comprehensive set of sequence analysis programs for the VAXQ26778432
A VH gene is located within 95 Kb of the human immunoglobulin heavy chain constant region genesQ28291466
Somatic generation of antibody diversityQ29616439
Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generationQ33764048
Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytesQ36229896
Lack of N regions in fetal and neonatal mouse immunoglobulin V-D-J junctional sequencesQ36353825
Proceedings of the National Academy of Sciences of the United States of AmericaQ1146531
Early human IgH gene assembly in Epstein-Barr virus-transformed fetal B cell lines. Preferential utilization of the most JH-proximal D segment (DQ52) and two unusual VH-related rearrangementsQ36356085
Novel rearrangements at the immunoglobulin D locus. Inversions and fusions add to IgH somatic diversityQ36356579
Organization of the Ig VH locus in mice and humansQ38706470
The mechanism of antigen receptor gene assemblyQ38722451
Nucleotide sequences of the cDNAs encoding the V-regions of H- and L-chains of a human monoclonal antibody specific to HIV-1-gp41.Q40522741
Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locusQ41091501
VH gene family utilization is regulated by a locus outside of the VH regionQ41955992
Are anti-arsonate antibody N-segments selected at both the protein and the DNA level?Q47688240
Diversity of immunoglobulin heavy chain gene segment rearrangement in B lymphoblastoid cell lines from X-linked agammaglobulinemia patientsQ48207079
Developmentally controlled expression of immunoglobulin VH genesQ48380478
Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.Q52244112
Preferential expression of VH5 and VH6 immunoglobulin genes in early human B-cell ontogenyQ69796815
Organization and evolution of variable region genes of the human immunoglobulin heavy chainQ70313336
At least five DH genes of human immunoglobulin heavy chains are encoded in 9-kilobase DNA fragmentsQ70387473
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
lymphocyteQ715347
gene rearrangementQ65350917
immunoglobulin genesQ70688789
P304page(s)247-251
P577publication date1992-01-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleRestricted utilization of germ-line VH3 genes and short diverse third complementarity-determining regions (CDR3) in human fetal B lymphocyte immunoglobulin heavy chain rearrangements
P478volume22

Reverse relations

cites work (P2860)
Q73481209Age‐related impaired affinity maturation and differential D‐JH gene usage in human VH6‐expressing B lymphocytes from healthy individuals
Q78427270An unrelated cytogenetic karyotype and intra-lineage shift at relapse of an aggressive paediatric B-precursor ALL
Q35428887Analysis of human monoclonal antibodies elicited by vaccination with a Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine.
Q48166985Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas
Q48083576B precursor acute lymphoblastic leukemia third complementarity-determining regions predominantly represent an unbiased recombination repertoire: leukemic transformation frequently occurs in fetal life
Q41146630Characterization of anti-sperm antibodies and their coding cDNA sequences by Epstein-Barr virus transformed B cell lines from lymphocytes of infertile women possessing anti-sperm antibodies
Q33192836Chromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire
Q36341119Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutation
Q52507703Concurrent presence of inv(14)(q11q32) and t(4;11)(q21;q23) in pre-B acute lymphoblastic leukemia.
Q38462172Development of the early B cell population in Xenopus
Q36902130Developmental progression of equine immunoglobulin heavy chain variable region diversity
Q35763473Ethnic differences of polymorphism of an immunoglobulin VH3 gene
Q47213323Ig heavy chain CDR3 size diversities are similar after conventional peripheral blood and ex vivo expanded hematopoietic cell transplants
Q74074341Immunoglobulin heavy chain junctional diversity in young and aged humans
Q49829351In-Depth Analysis of Human Neonatal and Adult IgM Antibody Repertoires
Q34384371Invariance and restriction toward a limited set of self-antigens characterize neonatal IgM antibody repertoires and prevail in autoreactive repertoires of healthy adults
Q48075371Location and sequence of rearranged immunoglobulin genes in human thymus
Q74774303Long-term kinetics of adult human antibody repertoires
Q36774868Mechanisms that generate human immunoglobulin diversity operate from the 8th week of gestation in fetal liver
Q52005635Memory B lymphocytes determine repertoire oligoclonality early after haematopoietic stem cell transplantation.
Q41401910Molecular characterization of monoclonal IgM derived from human B cell lines expressing the 4C9 rheumatoid factor associated idiotype
Q41339873Molecular mechanisms governing reading frame choice of immunoglobulin diversity genes
Q73923498Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions
Q68176920New nucleotide sequence data on the EMBL File Server
Q40676106Normal B lymphocyte differentiation
Q48056941Rabbit DQ52 and DH gene expression in early B-cell development
Q28290642Reconsidering the human immunoglobulin heavy-chain locus: 1. An evaluation of the expressed human IGHD gene repertoire
Q34981948Regulation and chance in the ontogeny of B and T cell antigen receptor repertoires
Q74128116Repertoire analysis in human immunoglobulin heavy chain minilocus transgenic, muMT/muMT mice
Q58393545Self-reactive antibodies (natural autoantibodies) in healthy individuals
Q48067974The VDJ repertoire expressed in human preB cells reflects the selection of bona fide heavy chains
Q41829277The human neonatal B cell response to respiratory syncytial virus uses a biased antibody variable gene repertoire that lacks somatic mutations
Q28247264The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses
Q39035263Timely and spatially regulated maturation of B and T cell repertoire during human fetal development
Q41545122Unequal signal and coding joint formation in human V(D)J recombination
Q52219682Usage of TCRAV and TCRBV gene families in human fetal and adult TCR rearrangements.
Q35884584Use of D gene segments with irregular spacers in terminal deoxynucleotidyltransferase (TdT)+/+ and TdT-/- mice carrying a human Ig heavy chain transgenic minilocus
Q41544908What limits affinity maturation of antibodies in Xenopus--the rate of somatic mutation or the ability to select mutants?

Search more.