Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time

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Hepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time is …
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scholarly articleQ13442814

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P356DOI10.1002/JMRI.25673
P698PubMed publication ID28225569

P50authorEun Young ChoQ63625073
Kwon-Ha YoonQ85825088
P2093author name stringYoung Hwan Lee
Yong Yeon Jeong
Chung Hwan Jun
Ki Jung Yun
Tae-Hoon Kim
Ki-Jong Kim
Hong Young Jun
Myeung Su Lee
Keum Ha Choi
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Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectinQ28588020
Design and validation of a histological scoring system for nonalcoholic fatty liver diseaseQ29614930
Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicityQ29614932
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The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy: a meta-analysisQ30497534
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Nonalcoholic fatty liver disease: quantitative assessment of liver fat content by computed tomography, magnetic resonance imaging and proton magnetic resonance spectroscopy.Q33515778
Quantification of muscle choline concentrations by proton MR spectroscopy at 3 T: technical feasibilityQ33520399
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Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cellsQ34152594
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Nonalcoholic fatty liver disease: from steatosis to cirrhosisQ36382279
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Experimental Nonalcoholic Steatohepatitis Induced by Neonatal Streptozotocin Injection and a High-Fat Diet in RatsQ36528723
Total creatine in muscle: imaging and quantification with proton MR spectroscopyQ36873813
Animal models of NASH: getting both pathology and metabolic context rightQ37254525
Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept StudyQ38582703
In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvateQ39981457
Proton NMR chemical shifts and coupling constants for brain metabolitesQ41742652
Clinical Features of Myocardial Triglyceride in Different Types of Cardiomyopathy Assessed by Proton Magnetic Resonance Spectroscopy: Comparison With Myocardial CreatineQ42864680
Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient dietQ43233397
Clinical features and outcomes of cirrhosis due to non-alcoholic steatohepatitis compared with cirrhosis caused by chronic hepatitis C.Q44190785
Steatohepatitis induced by intragastric overfeeding in miceQ46320547
Anomalous J-modulation effects on amino acids in clinical 3T MR spectroscopyQ46392159
Localized brain metabolite changes during visual sexual stimulation in postmenopausal women: a pilot study using functional magnetic resonance spectroscopyQ48243357
Noninvasive biomarkers for acute hepatotoxicity induced by 1,3-dichloro-2-propanol: hyperpolarized 13C dynamic MR spectroscopy.Q50781832
P433issue5
P921main subjectsteatohepatitisQ2335423
L-alanineQ218642
steatosisQ1365091
P304page(s)1298-1310
P577publication date2017-02-22
P1433published inJournal of Magnetic Resonance ImagingQ15761156
P1476titleHepatic Alanine Differentiates Nonalcoholic Steatohepatitis From Simple Steatosis in Humans and Mice: A Proton MR Spectroscopy Study With Long Echo Time
P478volume46