Pax: a murine multigene family of paired box-containing genes

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Pax: a murine multigene family of paired box-containing genes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/0888-7543(91)90151-4
P698PubMed publication ID1685142

P50authorUrban DeutschQ32420081
P2093author name stringSimon D
Gruss P
Walther C
Guenet JL
Plachov D
Jostes B
Balling R
Goulding MD
Deutsch U
P2860cites workThe molecular basis for metameric pattern in the Drosophila embryoQ114755591
P433issue2
P304page(s)424-434
P577publication date1991-10-01
P1433published inGenomicsQ5533503
P1476titlePax: a murine multigene family of paired box-containing genes
P478volume11

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cites work (P2860)
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Q72799522Fine genetic mapping of the proximal part of mouse chromosome 2 excludes Pax-8 as a candidate gene for Danforth's short tail (Sd)
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Q41676162Haplotype analysis of intra-specific backcross curly-tail mice confirms the localization of ct to chromosome 4.
Q47330288Homeodomain-interacting protein kinase phosphorylates the Drosophila Paired box protein 6 (Pax6) homologues Twin of eyeless and Eyeless
Q36566927Identification and characterization of a neuroretina-specific enhancer element in the quail Pax-6 (Pax-QNR) gene
Q39449324Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a possible role of Pax4 as a transcriptional repressor in the pancreas
Q24600089Identification of functional domains and evolution of Tc1-like transposable elements
Q38359317Identification of novel Pax-2 binding sites by chromatin precipitation
Q46939232Immunohistochemical localization of Pax6 in the developing tooth germ of mice
Q40177599Induction of multilineage markers in human myeloma cells and their down-regulation by interleukin 6.
Q34549454Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain
Q34067563Iris hypoplasia in mice that lack the alternatively spliced Pax6(5a) isoform
Q34822452Isolation and expression of a Pax-6 gene in the regenerating and intact Planarian Dugesia(G)tigrina.
Q37670506Isolation of a Pax-6 homolog from the ribbonworm Lineus sanguineus
Q24313356Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue
Q28303028Isolation of the Pax9 cDNA from adult human esophagus
Q34604788Large novel deletions detected in Chinese families with aniridia: correlation between genotype and phenotype
Q64448365Linkage mapping of the Aldo-2, Pax-5, Ambp , and D4H9S3E loci on mouse chromosome 4 in the region of homology with human chromosome 9
Q50534793Localization of the gene for branchiootorenal syndrome to chromosome 8q.
Q36797294Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition
Q28275505Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb
Q39555698Mapping gene regulatory circuitry of Pax6 during neurogenesis.
Q38353780Mapping of Pax-2 transcription activation domains
Q28265998Mapping of the human homologs of the murine paired-box-containing genes
Q59337332Mapping the Pax6 3' untranslated region microRNA regulatory landscape
Q36738873Maps from two interspecific backcross DNA panels available as a community genetic mapping resource
Q52597712MiR-144-3p promotes the tumor growth and metastasis of papillary thyroid carcinoma by targeting paired box gene 8.
Q40313088Molecular analysis of a human PAX6 homeobox mutant
Q33965422Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine
Q34230553Molecular basis of non-syndromic tooth agenesis: mutations of MSX1 and PAX9 reflect their role in patterning human dentition
Q35607397Molecular basis of otic commitment and morphogenesis: a role for homeodomain-containing transcription factors and signaling molecules
Q35191281Molecular basis of splotch and Waardenburg Pax-3 mutations
Q24604768Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes
Q35675696Mouse chromosome 1.
Q67896332Mouse chromosome 19
Q35675802Mouse chromosome 19.
Q35675740Mouse chromosome 2.
Q35675818Mouse chromosome 4.
Q35675830Mouse chromosome 6.
Q29617930Mouse small eye results from mutations in a paired-like homeobox-containing gene
Q33797133Multimarker quantitative real-time PCR detection of circulating melanoma cells in peripheral blood: relation to disease stage in melanoma patients
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Q28252261Mutations at the PAX6 locus are found in heterogeneous anterior segment malformations including Peters' anomaly
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Q70708772Mutations in the PAX3 gene causing Waardenburg syndrome type 1 and type 2
Q24322489Mutations in the paired domain of the human PAX3 gene cause Klein-Waardenburg syndrome (WS-III) as well as Waardenburg syndrome type I (WS-I)
Q36686647NF-HB (BSAP) is a repressor of the murine immunoglobulin heavy-chain 3' alpha enhancer at early stages of B-cell differentiation
Q38067378Neocortical arealization: evolution, mechanisms, and open questions
Q35874484Noggin is novel inducer of mesenchymal stem cell adipogenesis: implications for bone health and obesity
Q74452065Normal and rearranged PAX3 expression in human rhabdomyosarcoma
Q24517954Organisation of the human PAX4 gene and its exclusion as a candidate for the Wolcott-Rallison syndrome
Q24655113Osteoimmunology: interactions of the bone and immune system
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Q37775841PAX-5: a valuable immunohistochemical marker in the differential diagnosis of lymphoid neoplasms
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Q24515343PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin
Q47822208Paired box 7 (Pax7) gene: molecular characterisation, polymorphism and its association with growth performance in goose (Anser cygnoides).
Q28504907Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development
Q41029841Pax genes and skeletal development
Q33855370Pax genes and the differentiation of hormone-producing endocrine cells in the pancreas
Q35886629Pax genes in embryogenesis and oncogenesis
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Q41127733Pax-2, kidney development, and oncogenesis
Q38305493Pax-3-DNA interaction: flexibility in the DNA binding and induction of DNA conformational changes by paired domains.
Q48417513Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development
Q73174934Pax-5 is identical to EBB-1/KLP and binds to the VpreB and lambda5 promoters as well as the KI and KII sites upstream of the Jkappa genes
Q28570171Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters
Q42689153Pax-QNR/Pax-6, a paired- and homeobox-containing protein, recognizes Ets binding sites and can alter the transactivating properties of Ets transcription factors
Q24338309Pax1, a member of the paired box-containing class of developmental control genes, is mapped to human chromosome 20p11.2 by in situ hybridization (ISH and FISH)
Q39886410Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons
Q34310273Pax3 inhibits myogenic differentiation of cultured myoblast cells
Q37633128Pax3 modulates expression of the c-Met receptor during limb muscle development
Q73301463Pax4 regulatory elements mediate beta cell specific expression in the pancreas
Q28589877Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
Q28199296Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene
Q91829081Pax6 expression highlights regional organization in the adult brain of lungfishes, the closest living relatives of land vertebrates
Q43096272Pax6 is essential for lens fiber cell differentiation
Q48142489Pax7 is expressed in the capsules surrounding adult mouse neuromuscular spindles
Q37062080Pax8 has a critical role in epithelial cell survival and proliferation
Q32024327Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities.
Q33346071Perplexing Pax: from puzzle to paradigm.
Q41524945Perspectives on eye development
Q71740203Physiological activation of the IgH 3' enhancer in B lineage cells is not blocked by Pax-5
Q22251285Positional cloning of the mouse obese gene and its human homologue
Q36551779Quail Pax-6 (Pax-QNR) mRNAs are expressed from two promoters used differentially during retina development and neuronal differentiation
Q31154012Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer
Q33796997Serial monitoring of circulating melanoma cells during neoadjuvant biochemotherapy for stage III melanoma: outcome prediction in a multicenter trial
Q48472745Small eye (Sey): Cloning and characterization of the murine homolog of the human aniridia gene
Q28202114Structural and functional characterization of the human PAX7 5'-flanking regulatory region
Q24531533Structural defects of a Pax8 mutant that give rise to congenital hypothyroidism
Q57258271Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy
Q33851820Syndromes associated with Homo sapiens pol II regulatory genes
Q24316993Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency
Q40794335Tc1 transposase of Caenorhabditis elegans is an endonuclease with a bipartite DNA binding domain
Q36362957The B cell-specific transcription factor BSAP regulates B cell proliferation
Q73836155The C-terminal subdomain makes an important contribution to the DNA binding activity of the Pax-3 paired domain
Q35172685The Groucho-associated phosphatase PPM1B displaces Pax transactivation domain interacting protein (PTIP) to switch the transcription factor Pax2 from a transcriptional activator to a repressor
Q41301123The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype
Q38300712The PAX5 gene: a linkage and mutation analysis in candidate human primary immunodeficiencies
Q40636577The PAX6 gene is activated by the basic helix-loop-helix transcription factor NeuroD/BETA2.
Q36852666The Pax-5 gene is alternatively spliced during B-cell development
Q59069706The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas
Q44497136The Pax6 genes eyeless and twin of eyeless are required for global patterning of the ocular segment in the Tribolium embryo
Q92151823The Spectrum of PAX6 Mutations and Genotype-Phenotype Correlations in the Eye
Q33593944The beta subunit of voltage-gated Ca2+ channels interacts with and regulates the activity of a novel isoform of Pax6.
Q47775692The characterization of novel Pax genes of the sea urchin and Drosophila reveal an ancient evolutionary origin of the Pax2/5/8 subfamily
Q40721047The expression of the developmentally regulated proto-oncogene Pax-3 is modulated by N-Myc
Q49130128The gene encoding the central cannabinoid receptor is located in proximal mouse Chromosome 4.
Q64446105The genetic architecture of aniridia and Gillespie syndrome
Q28207886The human PAX6 gene is mutated in two patients with aniridia
Q33678646The incidence of PAX6 mutation in patients with simple aniridia: an evaluation of mutation detection in 12 cases.
Q36777403The molecular and genetic analysis of mouse development
Q35934032The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney
Q35716468The mouse genome: an overview
Q54445146The murine even-skipped-like gene Evx-2 is closely linked to the Hox-4 complex, but is transcribed in the opposite direction.
Q38318897The oncogenic potential of Pax genes
Q37585530The origin, molecular regulation and therapeutic potential of myogenic stem cell populations
Q40947266Theoretical approaches to the analysis of homeobox gene evolution
Q41170335Transcription factor genes and the developing eye: a genetic perspective
Q33665900Transcription factors for lens development assessed in vivo
Q37366553Transcriptional activities of the Pax6 gene eyeless regulate tissue specificity of ectopic eye formation in Drosophila.
Q40665726Transcriptional regulation of gene expression: mechanisms and pathophysiology
Q53622866Unveiling differentially expressed genes upon regulation of transcription factors in sepsis.
Q24530630WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8
Q28181722Waardenburg's syndrome patients have mutations in the human homologue of the Pax-3 paired box gene
Q32106979Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development.
Q47964657Xenopus Pax-2/5/8 orthologues: novel insights into Pax gene evolution and identification of Pax-8 as the earliest marker for otic and pronephric cell lineages
Q47073777Zebrafish Pax9 encodes two proteins with distinct C-terminal transactivating domains of different potency negatively regulated by adjacent N-terminal sequences
Q44725306Zebrafish pax[b] is involved in the formation of the midbrain-hindbrain boundary

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