Digital image analysis of Ki67 proliferation index in breast cancer using virtual dual staining on whole tissue sections: clinical validation and inter-platform agreement

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Digital image analysis of Ki67 proliferation index in breast cancer using virtual dual staining on whole tissue sections: clinical validation and inter-platform agreement is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10549-018-4669-2
P932PMC publication ID5882622
P698PubMed publication ID29349710

P50authorBert van der VegtQ50889999
P2093author name stringGeertruida H de Bock
Harry Hollema
Henk J Buikema
Timco Koopman
P2860cites workCell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67Q72743242
How reliable is Ki-67 immunohistochemistry in grade 2 breast carcinomas? A QA study of the Swiss Working Group of Breast- and GynecopathologistsQ28729183
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A methodology for comprehensive breast cancer Ki67 labeling index with intra-tumor heterogeneity appraisal based on hexagonal tiling of digital image analysis data.Q31007935
A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissueQ33739487
Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaborationQ33915010
Proliferative activity in human breast cancer: Ki-67 automated evaluation and the influence of different Ki-67 equivalent antibodiesQ34775344
Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working groupQ35552069
A Comparison of Visual Assessment and Automated Digital Image Analysis of Ki67 Labeling Index in Breast CancerQ35940233
Automated quantification of proliferation with automated hot-spot selection in phosphohistone H3/MART1 dual-stained stage I/II melanoma.Q36783370
An international Ki67 reproducibility studyQ37463125
Image analysis and machine learning in digital pathology: Challenges and opportunitiesQ38379203
Strategies for developing Ki67 as a useful biomarker in breast cancerQ38568750
An international study to increase concordance in Ki67 scoringQ39037175
Proliferation assessment in breast carcinomas using digital image analysis based on virtual Ki67/cytokeratin double stainingQ39694709
Digital image analysis outperforms manual biomarker assessment in breast cancer.Q39967968
Automated quantification of MART1-verified Ki67 indices by digital image analysis in melanocytic lesions.Q40037909
Comparison of the effect of different techniques for measurement of Ki67 proliferation on reproducibility and prognosis prediction accuracy in breast cancerQ40061893
The region-of-interest size impacts on Ki67 quantification by computer-assisted image analysis in breast cancer.Q40299367
Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinomaQ40348126
Standardized Ki67 Diagnostics Using Automated Scoring--Clinical Validation in the GeparTrio Breast Cancer Study.Q41698029
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimage analysisQ860755
P304page(s)33-42
P577publication date2018-01-18
P1433published inBreast Cancer Research and TreatmentQ326085
P1476titleDigital image analysis of Ki67 proliferation index in breast cancer using virtual dual staining on whole tissue sections: clinical validation and inter-platform agreement
P478volume169