Activating KRAS mutations are characteristic of oncocytic sinonasal papilloma and associated sinonasal squamous cell carcinoma.

scientific article published on 28 May 2016

Activating KRAS mutations are characteristic of oncocytic sinonasal papilloma and associated sinonasal squamous cell carcinoma. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PATH.4750
P698PubMed publication ID27234382

P50authorKojo Elenitoba-JohnsonQ62479915
Megan S LimQ62479921
Aaron UdagerQ37830170
Noah A BrownQ38321139
Bayardo Perez-OrdonezQ49735119
P2093author name stringRaja R Seethala
O Hans Iwenofu
Jonathan B McHugh
Bryan L Betz
Virginia A Livolsi
Evgeny Yakirevich
Kathleen T Montone
Helmut C Weigelin
Kathleen E DuRoss
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Schneiderian papillomas and nonsalivary glandular neoplasms of the head and neckQ34571127
Comparative analysis of KRAS codon 12, 13, 18, 61, and 117 mutations using human MCF10A isogenic cell linesQ35109213
K-rasG12V transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysisQ35670198
High-Frequency Targetable EGFR Mutations in Sinonasal Squamous Cell Carcinomas Arising from Inverted Sinonasal Papilloma.Q35869894
Prognostic and Predictive Roles of KRAS Mutation in Colorectal CancerQ36396396
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colonQ36697241
EGFR Expression and KRAS and BRAF Mutational Status in Intestinal-Type Sinonasal AdenocarcinomaQ36790406
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Sinonasal inverted papilloma associated with malignancy: the role of human papillomavirus infection and its implications for radiotherapyQ37958139
MEK in cancer and cancer therapyQ38152195
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KRAS allel-specific activity of sunitinib in an isogenic disease model of colorectal cancer.Q39186065
KRASG12V Enhances Proliferation and Initiates Myelomonocytic Differentiation in Human Stem/Progenitor Cells via Intrinsic and Extrinsic PathwaysQ39618355
AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclQ40093939
Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey.Q40346822
Epidermal growth factor receptor expression and KRAS and BRAF mutations: study of 39 sinonasal intestinal-type adenocarcinomasQ50887769
EGFR status and KRAS/BRAF mutations in intestinal-type sinonasal adenocarcinomasQ54288195
P433issue4
P921main subjectsinonasal papillomaQ18975137
P304page(s)394-398
P577publication date2016-07-01
P1433published inJournal of PathologyQ400296
P1476titleActivating KRAS mutations are characteristic of oncocytic sinonasal papilloma and associated sinonasal squamous cell carcinoma
P478volume239

Reverse relations

cites work (P2860)
Q91661897Comparative transcriptome analysis of sinonasal inverted papilloma and associated squamous cell carcinoma: Out-HOXing developmental genes
Q92792168Frequent KRAS and HRAS mutations in squamous cell papillomas of the head and neck
Q88739010Genetic mutation analysis of the malignant transformation of sinonasal inverted papilloma by targeted amplicon sequencing
Q52673137Genetic profiling of poorly differentiated sinonasal tumours.
Q47584630Human papillomavirus (HPV) and somatic EGFR mutations are essential, mutually exclusive oncogenic mechanisms for inverted sinonasal papillomas and associated sinonasal squamous cell carcinomas
Q89485519MR imaging and CT features of oncocytic papilloma of the sinonasal tract with comparison to inverted papilloma
Q39263682New tumor entities in the 4th edition of the World Health Organization classification of head and neck tumors: Nasal cavity, paranasal sinuses and skull base.
Q39189224OSPs and ESPs and ISPs, Oh My! An Update on Sinonasal (Schneiderian) Papillomas
Q55228997Oncocytic Schneiderian papilloma-associated adenocarcinoma and KRAS mutation: A case report.
Q92740797Recurrent KRAS mutations identified in papillary renal neoplasm with reverse polarity-a comparative study with papillary renal cell carcinoma
Q102141602TP53 mutations and CDKN2A mutations/deletions are highly recurrent molecular alterations in the malignant progression of sinonasal papillomas

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